SABIIA - Sistema Aberto e Integrado de Informação em Agricultura (Sabiia)

Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180

Kabu,Mustafa; Tosun,Murat; Elitok,Bülent; Akosman,Murat Sirri.

Boron is an essential element for life and intake via different sources into the body. Because effects of boron and compounds on the body has not been studied enough especially in tissue level, we planned this study to evaluate the effects of borax the most intaken form of boron compound on different intraabdominal organs histologically and also clinically. 42 male rats divided into equal 7 groups and different toxicological doses consistent with its LD50 dose (5000 mg/kg/d) were administered by gavage except control and sham groups. In the study, 2 different kinds of borax one of which was produced for research and the other for agriculture but the same formulation, were used and their effects were also compared. As a result it was found that borax did...

Tipo: Journal article

Palavras-chave: Boron; Borax; Inflammatory bowel disease; Histopathology; Toxicology.

Ano: 2015

URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000100040

da Silva,Ivanise Brito; Lima,Izabela Rangel; Santana,Marllon Alex Nascimento; Leite,Roberta Maria Pereira; Leite,Sônia Pereira.

Indigofera suffruticosa is a plant generally used to treat infectious and inflammatory processes. This work aims to evaluate the histopathological changes in the liver tissue of mice with Sarcoma 180 after subchronic treatment with aqueous extract obtained by infusion and maceration of Indigofera suffruticosa leaves. Male mice were divided into four groups of six animals: G1, G2 and G3 patients with Sarcoma 180 and Sarcoma 180 G4 without sarcoma. G1 and G2 were treated with infusion mashing respectively (50 mg/kg ip); G3 and G4 controls received saline (15 ml/kg ip). The histopathological and morphometric analysis of liver tissue after subchronic treatment with aqueous extracts by infusion and maceration of the groups G1, G2 and G4 were similar and showed...

Tipo: Journal article

Palavras-chave: Liver; I. suffruticosa; Histopathology; Histomorphometry; Sarcoma 180.

Ano: 2014

URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400017

Sesame radiatum Phytoestrogens Stimulate Spermatogenic Activity and Improve Sperm Quality in Adult Male Sprague Dawley Rat Testis

Histopathologic Effect of Persea americana Aqueous Leaves Extract on the Liver and Kidney of Weaner Rabbits (California Species)

Shittu,Lukeman, A. J.; Shittu,Remilekun, K.; Adesite,Samson, O.; Ajala,M. Oluwole; Bankole,Munir, A.; Benebo,A. S.; Tayo,A. O.; Ogundipe,Olufemi, A.; Ashiru,Oladapo, A..

Increasing concern has been expressed about the declining sperm count of humans and the potential environmental effects of both synthetic and natural estrogenic endocrine disruptors (EEDs) on human reproductive health in the last few decades. However, due to paucity of knowledge, we evaluate the chronic reproductive toxicity of sesame phytoestrogenic lignans on the male Sprague Dawley (SD) rats' testis. Thirty adult male SD rats weighing 150-200g were divided into three groups. Two treated groups received a daily dose of aqueous leaves extract of Sesamum radiatum at 14.0 mg/kg bw and 28.0mg /kg bw respectively via gastric gavage, while equal volume of normal saline was administered to the control group for six weeks. Seminal analysis and hormonal assay...

Tipo: Journal article

Palavras-chave: Testis; Sesame leaves; Histopathology; Hormonal assay; Seminal analysis; SD Rats.

Ano: 2008

URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000300022

Histopathological changes in albino mouse testis induced by the administration of Tityus n. sp. venom

Adisa,J. O; Ajayi,Y; Egbujo,E. C.

Persea americana (avocado) is widely grown in parts of Southeastern Nigeria and used as a medicinal plant in the treatment of several ailments by alternative medical practitioners but very little research has been carried out on its pharmacotoxicity. This study therefore intends to study the histopathologic effect(s) of Persea americana aqueous leaf extract on the liver and kidneys of rabbits. Fresh leaves of Persea americana were processed using the Soxhlet extraction to obtain the aqueous extract. Three (3) groups of weaner rabbits namely the control, the recommended dose and the high dose groups were given water, 75mg/kg/ and 150mg/kg per day of the extract respectively for 28 days. The animals were sacrificed, the liver and kidney were harvested, fixed...

Tipo: Journal article

Palavras-chave: Persea Americana; Liver; Kidney; Histopathology.

Ano: 2011

URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400053

J. Venom. Anim. Toxins

PENNA-VIDEAÚ,S.; CERMEÑO-VIVAS,J.; MORENO-MARVAL,M.; QUIROGA-NOTTI,M..

Scorpion envenoming is a public health concern in northeastern Venezuela. Specimens of the genus Tityus are responsible for most of these. In experimental animals, Tityus venom produces histopathological changes in the skeletal muscle and pancreas, but its toxicity to the reproductive system has not been studied. The aim of this work is to describe the histopathological changes in testis and epididymis of albino mice induced by the administration of Tityus n. sp. venom. Sub-lethal doses of venom (3.75 mg/g mouse) were administered intramuscularly (IM) daily for 4 days. On the fifth day, the animals were sacrificed and the testes and epididymes were quickly removed and processed for light microscopy. The venom induced alterations in spermatogenesis. Sertoli...

Bothrops alternatus ENVENOMING IN YOUNG DOGS

Palavras-chave: Testis; Sertoli cell; Epididymis; Scorpion; Venom; Mouse; Histopathology.

Ano: 2000

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200003

J. Venom. Anim. Toxins

PEREZ,O. A. DE; KOSCINCZUK,P.; FLINTA,S. M.; MAIDANA,H. R.; SANCHEZ NEGRETTE,M..

Bothrops alternatus venom was intramuscularly inoculated (3 mg/kg) into 12 dogs, 30 to 65 days old. Spontaneous bleeding commenced twenty minutes later. Blood samples obtained 3 and 20 minutes after venom inoculation presented spontaneous clotting formation. Plasmatic fibrinogen decreased within 3 minutes. Partial thromboplastin time (PTT) and one-stage prothrombin time (PT) were found. Plasma did not coagulate 40 minutes after inoculation. Platelet counts did not vary but their function was altered. Histopathology pointed out severe muscular necrosis and massive hemorrhage in the inoculation area. Regional ganglia showed intense hemorrhage. The 45 and 65-day-old animals showed alveolar thickening of the septum and generalized congestion, but the...

Tipo: Info:eu-repo/semantics/other

Palavras-chave: Dogs; Bothrops alternatus; Coagulation; Histopathology.

Ano: 1997

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000100006

Technetium-99m-labeled deoxynivalenol from Fusarium mycotoxin alters organ toxicity in BALB/c mice by oral and intravenous route

Chattopadhyay,P; Pandey,A; Goyary,D; Chaurasia,A; Singh,L; Veer,V.

The toxicity of deoxynivalenol, both intravenously and orally, was investigated in male and female BALB/c mice. Technetium-99m (99m Tc)-labeled deoxynivalenol was administered to mice by tail vein injection and orally dosed. Distribution of labeled deoxynivalenol at 26 hours was monitored by gamma-scintigraphy. In the evaluated organs, the accumulation of radioactive deoxynivalenol was correlated with the amount of radioactivity. In addition, the toxicity of deoxynivalenol was measured by biochemical assays followed by histopathological findings. Kidney and hepatic marker enzymes were significantly increased in intravenously administered deoxynivalenol as compared to orally treated mice. Intravenously treated mice showed severe damage in liver and kidney...

Experimental envenomation with Crotalus durissus terrificus venom in dogs treated with antiophidic serum - part II: laboratory aspects, electrocardiogram and histopathology

Palavras-chave: Technetium-99m (99mTc); Deoxynivalenol; Biodistribution; Toxicity; Histopathology.

Ano: 2012

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300002

Nogueira,R. M. B.; Sakate,M.; Sangiorgio,F.; Laposy,C. B.; Tostes,R. A..

The present work shows laboratory aspects, electrocardiogram and histopathology results during experimental envenomation by Crotalus durissus terrificus in dogs treated with antiophidic serum. Twenty-one dogs were divided into three groups of seven animals each. Group I received 1mg/kg venom (sc); Group II received 1mg/kg venom (sc), 50mg antiophidic serum (iv) and fluid therapy including 0.9% NaCl solution (iv); and Group III received 1mg/kg venom (sc), 50mg antiophidic serum (iv) and fluid therapy including 0.9% NaCl solution containing sodium bicarbonate diluted to the dose of 4mEq/kg. Urinalysis showed brown urine, proteinuria, occult blood and myoglobinuria. Respiratory acidosis and hypotension were also observed. At the venom inoculation site, there...

Clostridium perfringens types A and D associated with enterotoxemia in an 18-month-old goat

Palavras-chave: Crotalus durissus terrificus; Dog; Laboratory aspects; Histopathology.

Ano: 2007

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000400011

Miyashiro,S.; Nassar,A. F. C.; Del Fava,C.; Cabral,A. D.; Silva,M..

Postmortem examination of a Boer buck that died peracutely revealed bowel and liver diffusely congested and edematous. Kidney was apparently edematous. Clostridium perfringens type A was isolated from bowel and type D from kidney. Microscopic examination revealed large areas of necrosis in the renal cortex and medulla (pulpy kidney disease), hyperemia and centrilobular necrosis of the liver, necrosis of the small-intestine wall, pulmonary edema and congestion, intense hyperemia of the cerebellum, hyperemia and edema of the brain.

Histopathological evaluation in experimental envenomation of dogs with Crotalus durissus terrificus venom

Palavras-chave: Goats; Enterotoxemia; Pulpy kidney disease; Clostridium perfringens type A; Clostridium perfringens type D; Histopathology.

Ano: 2007

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000400017

Sangiorgio,F.; Sakate,M.; Nogueira,R. M. B.; Tostes,R. A..

The present work evaluated histopathological aspects in experimental envenomation of dogs with Crotalus durissus terrificus venom. Twenty-eight mixed breed adult dogs were divided into three groups of seven animals each: Group I - only venom; Group II - venom + 50ml antiophidic serum + fluid therapy; Group III - venom + 50ml antiophidic serum + fluid therapy + urine alkalization. Lyophilized venom of Crotalus durissus terrificus was reconstituted in saline solution and inoculated subcutaneously at the dose of 1mg/kg body weight. Three animals of each group were subjected to euthanasia, and their muscular tissue, brain, spleen, kidneys, heart, lungs, stomach, small and large intestines, and popliteal lymph node fragments were collected for histopathological...

Systemic effects induced by intralesional injection of ω-conotoxin MVIIC after spinal cord injury in rats

Palavras-chave: Histopathology; Crotalus durissus terrificus; Dogs; Treatment; Intoxication.

Ano: 2008

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000100007

Oliveira,Karen M; Silva,Carla Maria O; Lavor,Mário Sérgio L; Rosado,Isabel R; Fukushima,Fabíola B; Assumpção,Anna Luiza FV; Neves,Saira MN; Motta,Guilherme R; Garcia,Fernanda F; Gomez,Marcus Vinícius; Melo,Marília M; Melo,Eliane G.

Background:Calcium channel blockers such as conotoxins have shown a great potential to reduce brain and spinal cord injury. MVIIC neuroprotective effects analyzed in in vitromodels of brain and spinal cord ischemia suggest a potential role of this toxin in preventing injury after spinal cord trauma. However, previous clinical studies with MVIIC demonstrated that clinical side effects might limit the usefulness of this drug and there is no research on its systemic effects. Therefore, the present study aimed to investigate the potential toxic effects of MVIIC on organs and to evaluate clinical and blood profiles of rats submitted to spinal cord injury and treated with this marine toxin. Rats were treated with placebo or MVIIC (at doses of 15, 30, 60 or 120...

Histopathological alterations in Astyanax bifasciatus (Teleostei: Characidae) correlated with land uses of surroundings of streams

Palavras-chave: Conus magus; Cone snail; Histopathology; Hematology; Biochemistry.

Ano: 2014

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200311

Neotropical Ichthyology

Nimet,Jardel; Amorim,João Paulo de Arruda; Delariva,Rosilene Luciana.

ABSTRACT This study evaluated gills and liver of Astyanax bifasciatus as histological biomarkers for biomonitoring of streams along areas with different land uses. The fish were collected by electrofishing in six streams in the basin of the lower Iguaçu River. The objective was to correlate the presence and degree of histopathological alterations of gills and liver with the environmental variables among streams along different land uses. The low frequency of histopathological alterations found in fish from the forest streams suggested normal organ functioning. In fish from the rural and urban streams, the histopathological alterations occurred were in higher frequency, indicated light to moderate damage in gills and liver of fish from the rural streams,...

Studies of Liver of Mice in the Course of an Experimental Infection with Babesia microti. I : Histopathological Changes and Changes in the Glycogen Content

Palavras-chave: Biomarkers; Fish; Histopathology; Lotic environments; Urban impact.

Ano: 2018

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-62252018000100216

OAK

Kuzna-Grygiel, Wanda; Kolodziejczyk, Lidia.

Palavras-chave: Babesia microti; Liver; Histopathology; Glycogen.

Ano: 2000

URL: http://ir.obihiro.ac.jp/dspace/handle/10322/333

Studies of Liver of Mice in the Course of an Experimental Infection with Babesia microti. Ⅱ : Histopathological Studies on Oxidative and Antioxidative Enzymes

OAK

Kuzna-Grygiel, Wanda; Kolodziejczyk, Lidia.

Palavras-chave: Babesia microti; Liver; Histopathology.

Ano: 2000

URL: http://ir.obihiro.ac.jp/dspace/handle/10322/334

Manual de métodos parasitológicos e histopatológicos en piscicultura

OceanDocs

Keim, Albert.

Recientes problemas provocados por epiemias de infecciones de Ichthyophthirius multifiliie en la cría de bagre negro (Rhandia sapo) cultivado por el Departamento de Acuicultura del INAPE de Uruguay, y el conocimiento de que todos los piscicultores tienen problemas con los parásitos, constituyeron la base y antecedente para el inicio de un programa de investigaciones parasitológicas. Este programa incluyó. 1) Disección de bagres capturados en Laguna de Sauce y colecta de parásitos. 2) Disección de bagres cultivados en el Laboratorio y en los estanques de INAPE, y colecta de parásitos. 3) Identificación de los parásitos recolectados. 4) Elaboración de un manual que recopila los métodos más comunmente utilizados en parasitología e histopatología en la...

Tipo: Report

Palavras-chave: Fish diseases; Parasitic diseases; Fish culture; Parasitology; Histopathology; Manuals; Ichthyophthirius.

Ano: 1982

URL: http://hdl.handle.net/1834/4913

Hepatopancreatitis necrotizante (NHP). Identificación etiológica por métodos histopatológicos y moleculares en el camarón de cultivo Litopenaeus vannamei

OceanDocs

Rubio, M.; Artiles, A.; Silveira, R.; Osmel García; González, N..

Tipo: Journal Contribution

Palavras-chave: Histopathology.

Ano: 2012

URL: http://hdl.handle.net/1834/4657

Bonamia sp. (Protozoa, Haplosporidia) parásito de Ostrea puelchana D’Orbigny, (Mollusca, Bivalvia) en el Golfo San Matías (Patagonia Argentina): Histopatología, identificación e infección

OceanDocs

Kroeck, M.A..

Los moluscos bivalvos son organismos sedentarios que establecen una relación íntima no sólo entre ellos, sino también con el espacio que ocupan y con sus condiciones fisicoquímicas. Sus poblaciones pueden ser hospedadoras de múltiples organismos patógenos (virus,bacterias, hongos, protistas y metazoos), cuya presencia es regulada eficazmente a niveles infra, meta y suprapoblacionales en ambientes silvestres, no provocando, salvo excepcionalmente, impactos severos. Los cultivos a escala comercial producen concentraciones de individuos, con la consiguiente alteración del medio y del equilibrio natural en la relación parásito-hospedador, generándose condiciones apropiadas para el desarrollo de enfermedades. Entre los años 1995 y 1996 se instala, en la zona...

Tipo: Theses and Dissertations

Palavras-chave: Fishery biology; Marine molluscs; Parasitology; Protozoan diseases; Histopathology; Spatial distribution; Environmental conditions; Methodology; Examinations.

Ano: 2005

URL: http://hdl.handle.net/1834/5244

Host-parasite relationship during Epistylis sp. (Ciliophora: Epistylididae) infestation in farmed cichlid and pimelodid fish

PAB

Pádua,Santiago Benites de; Martins,Maurício Laterça; Valladão,Gustavo Moraes Ramos; Utz,Laura; Zara,Fernando José; Ishikawa,Márcia Mayumi; Belo,Marco Antonio de Andrade.

Abstract: The objective of this work was to describe the host-Epistylis sp. relationship during infestation on farmed fish. Five Nile tilapia (Oreochromis niloticus) and ten hybrid surubim catfish (Pseudoplatystoma reticulatum x P. corruscans), all diseased, were used for in vivo morphological analysis of sessile peritrichs by contrast microscopy. Fragments of infected tissues were subjected to histological processing and scanning electron microscopy. Epistylis sp. caused hemorrhagic ulcer disease, and cichlids were more prone to develop infestations throughout the body surface due to the attachment of the colonies to the scales, which did not occur with pimelodids. Multifocal granulomatous dermatitis was observed, associated with the hydropic degeneration...

The Preventive Effects of Different Doses of Glucomannan on Experimental Aflatoxicosis in Japanese Quails

Palavras-chave: Oreochromis niloticus; Pseudoplatystoma reticulatum; Pseudoplatystoma corruscans; Histopathology; Pathogenesis; Sessile peritrich..

Ano: 2016

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2016000500520

Rev. Bras. Ciênc. Avic.

Yavuz,O; Özdemir,Ö; Ortatatli,M; Atalay,B; Hatipoglu,F; Terzi,F.

ABSTRACT This experimental study was performed to investigate whether there is a protective effect of different doses of Glucomannan using against aflatoxicosis in Japanese quail, and pathological changes and relative organ weights were compared. In the experiment, 60 one-day old male Japanese quails were used as divided into six different groups. Experimental groups were designated as Control(C), aflatoxin(A), glucomannan(GM), 2-fold dose of glucomannan(2GM), aflatoxin+glucomannan(A+GM) and aflatoxin+2-fold dose of glucomannan(A+2GM). While control group quails fed the standard ration as ad libitum, other groups were fed with the administrations additionally to standard diet respectively; 2mg/kg of aflatoxin to group A, 1g/kg of glucomannan to group GM,...

Experimental infection of commercial layers with wild or attenuated Salmonella Gallinarum mutant strains: anatomic pathology, total blood cell count and serum protein levels

Palavras-chave: Aflatoxin; Glucomannan; Histopathology; Quail.

Ano: 2017

URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2017000300409

Rev. Bras. Ciênc. Avic.

Garcia,KO; Berchieri Jr.,A; Santana,AM; Alarcon,MFF; Freitas Neto,OC; Fagliari,JJ.

The aim of the present study was to comparatively evaluate hemogram, blood serum components and anatomopathologic alterations in commercial layers experimentally challenged with an attenuated vaccine candidate strain (SG∆cobS∆cbiA) and other two pathogenic strains (SGDcobS and SGNalr) of Gallinarum (SG). In total, 280 commercial layers were randomly divided into 4 groups (G1, G2, G3 and G4). At five days of age, birds from groups G1 received approximately 107 colony forming units (CFU) of SGDcobS; meanwhile birds from group G2 and G3 received the same dose of SGNalr and SG∆cobS∆cbiA, respectively. Birds from G4 were not infected. At 24 hours before (DBI) and 24 hours after (1 DAI), and three (3 DAI), five (5 DAI), seven (7 DAI) ten (10 DAI), and fifteen...