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| Registros recuperados: 27 | |
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| The possibility of producing neutralizing antibodies against the lethal effects of scorpion toxins was evaluated in the mouse model by immunization with an immunogen devoid of toxicity. A toxic fraction (5 mg) from the venom of the scorpion Tityus serrulatus was entrapped in sphingomyelin-cholesterol liposomes. The liposomes were treated for 1 h at 37oC with a 1% (w/w) trypsin solution in 0.2 M sodium carbonate buffer, pH 8.3. This treatment led to a strong reduction in venom toxicity. Immunization was performed as follows: mice were injected sc with 20 µg of the liposome-entrapped toxic fraction on days 1 and 21 and a final injection (20 µg) was administered ip on day 36. After injection of the immunogen, all mice developed an IgG response which was shown... |
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Palavras-chave: Liposomes; Neutralizing antibodies; Tityus serrulatus; Immunization; Toxins. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000700010 |
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| Basybekov,Sovetzhan Z.; Bazarbayev,Marat B.; Yespembetov,Bolat A.; Mussaeva,Assiya; Kanatbayev,Serik G.; Romashev,Kanapya M.; Dossanova,Aigul K.; Yelekeyev,Tokseiit A.; Akmatova,Elmira K.; Syrym,Nazym S.. |
| Abstract Tuberculosis is a serious disease of humans and animals, caused by bacteria of the Mycobacterium genus. This leads to complications in the life of the sick person, and subsequently to death. The cattle, who have been diagnosed with this bacterium, are usually sent to the slaughter, with the result that their livestock is reduced. Mycobacteriosis is also a disease, after determining which cattle are most often sent to slaughter. Such a reduction in livestock numbers has a negative effect on the economy. Of the 300 samples from the animals, 25 cultures of atypical bacteria responding to tuberculin were isolated. A series of tests - intravenous tuberculin test, ophthalmic test, palpebral test, "ZhAT" test, showed that most of the tuberculosis changes... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cattle; Atypical mycobacterium; Tuberculin skin test; Palpebral method; Immunization. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000200329 |
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| Schillings Neto,Ernest; Nogueira,Eriklis; Jardim,Rodrigo; Abreu,Urbano Gomes Pinto de; Sterza,Fabiana Andrade de Melo; Pellegrin,Aiesca Oliveira; Juliano,Raquel Soares. |
| ABSTRACT: This study evaluated the reproductive performance of Nellore heifers without previous vaccination undergoing fixed-time artificial insemination (FTAI) and subsequent natural breeding under different vaccination protocols against infectious bovine herpesvirus 1 (BHV-1), bovine viral diarrhea virus (BVDV), and bovine leptospirosis (BL). A total of 763 animals were included; the group assignment was as follows: T1, control without vaccination; T2, vaccination against BL; T3, vaccination against BHV-1and BVDV; T4,vaccination against combination of BL + BHV-1and BVDV. Vaccination was started 30 days before FTAI (D-40), and a booster dose was administered at D-10. Serological tests were used to verify the occurrence rate of natural infection by BL,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Beef cattle; Immunization; Leptospirosis; Pregnancy rate; Viral diseases. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019001100701 |
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| Registros recuperados: 27 | |
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