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Determination of potency and paraspecific effects of Androctonus crassicauda (Olivier, 1807) antivenom against Mesobuthus gibbosus (Brullé, 1832) venom (Scorpiones: Buthidae) J. Venom. Anim. Toxins incl. Trop. Dis.
Ozkan,O.; Adiguzel,S.; Kar,S.; Yakistiran,S.; Cesaretli,Y.; Karaer,K. Z..
Scorpion envenomation remains a real health problem in many countries. In scorpionism cases, it is often recommended that patients be treated with species-specific antivenom. Androctonus crassicauda venom has been used as antigen for antivenom production in Turkey, where this antivenom, called Turkish antivenom, has also been effective in the treatment of envenomation caused by species other than A. crassicauda. The present study aimed at determining the paraspecific effects and potency of the Turkish antivenom against Mesobuthus gibbosus (Brullé, 1832) venom. To assess the venom toxicity and the antivenom efficacy, we determined the Minimum Lethal Dose (MLD) and the Minimum Effective Dose (MED) instead of LD50 and ED50, respectively. Androctonus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Antivenom; Androctonus crassicauda; Mesobuthus gibbosus; Paraspecific activity.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000200008
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The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas J. Venom. Anim. Toxins incl. Trop. Dis.
Rodríguez-Ravelo,Rodolfo; Coronas,Fredy I V; Zamudio,Fernando Z; González-Morales,Lidia; López,Georgina Espinosa; Urquiola,Ariel Ruiz; Possani,Lourival D.
Backgound The venom of the Cuban scorpion Rhopalurus junceus is poorly study from the point of view of their components at molecular level and the functions associated. The purpose of this article was to conduct a proteomic analysis of venom components from scorpions collected in different geographical areas of the country. Results Venom from the blue scorpion, as it is called, was collected separately from specimens of five distinct Cuban towns (Moa, La Poa, Limonar, El Chote and Farallones) of the Nipe-Sagua-Baracoa mountain massif and fractionated by high performance liquid chromatography (HPLC); the molecular masses of each fraction were ascertained by mass spectrometry analysis. At least 153 different molecular mass components were identified among...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cuba; Hyaluronidase; Peptides; Phospholipase; Proteomics; Rhopalurus junceus; Scorpion.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992013000100309
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Effects of Androctonus crassicauda (Olivier, 1807) (scorpiones: buthidae) venom on rats: correlation among acetylcholinesterase activities and electrolytes levels J. Venom. Anim. Toxins incl. Trop. Dis.
Ozkan,O.; Adiguzel,S.; Kar,S.; Kurt,M.; Yakistiran,S.; Cesaretli,Y.; Orman,M.; Karaer,Z..
Scorpions can be considered living fossils because they have changed so little during the last 400 million years. They are venomous arthropods of the Arachnida class and regarded as relatives of spiders, ticks and mites. The aim of the present study was to evaluate the toxicity of Androctonus crassicauda (Olivier, 1807) venom and its effects on the acetylcholinesterase (AchE) activity and on electrolytes levels in rats. Animals were divided into seven groups of five rats each. Test groups received 250µg/kg of venom solution while control group was treated with 200µl of physiological saline solution (PSS). Blood samples were collected from the animals on the 1st, 2nd 4th, 8th, 12th, and 24th hours after subcutaneous injection of venom. Animals were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Androctonus crassicauda; Venom; Acetylcholinesterase; Electrolytes.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000100005
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Symptom patterns in adult patients stung by scorpions with emphasis on coagulopathy and hemoglubinuria J. Venom. Anim. Toxins incl. Trop. Dis.
Rahmani,AH; Jalali,A.
The aim of this retrospective descriptive study was to highlight clinical manifestations 24-48 hours following referral of adult patients stung by scorpions. This study contains clinical records of 290 patients admitted to Razi Hospital due to scorpion stings in Ahvaz, Khuzestan province from 2004 to 2005. The most prevalent patient age range was 15-20 years (30.3%). The most common sting location (41.3%) was the upper extremity; nearly half (49.6%) had been admitted within 6-24 hours following sting, while a large majority (85.5%) were hospitalized for 24-48 hours. A total of 116 (40%) patients presented hemoglobinuria. Contrary to available prior reports, the symptoms in none of the patients were accompanied by neurological manifestations. Kidney...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Scorpion; Stings; Signs and symptoms; Coagulopathy; Hemoglobinuria.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000400011
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Risk factors for scorpion stings in the beni mellal province of morocco J. Venom. Anim. Toxins incl. Trop. Dis.
Charrab,N; El Oufir,R; Soulaymani,A; Semlali,I; Mokhtari,A; Soulaymani,R.
Scorpion stings comprise a serious problem throughout the globe, especially in regions where they are more frequent. In Morocco, Beni Mellal is one of the provinces most affected by this burden. This study aimed to trace the epidemiological profile of scorpion stings in Beni Mellal in order to improve patient care and prevent both morbidity and mortality. Our work is a retrospective study of scorpion stings based on medical charts of Beni Mellal. From 2002 to 2007, 8,340 cases were registered in this province with an average incidence of 1.36‰. The stings were more frequent in summer months, particularly July and August, and between 6 p.m. and 6 a.m. (59.8%). The average age of victims was 26.54 ± 18.42 years. Children were affected in 30.3% of the cases....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Epidemiology; Scorpion; Register; Beni Mellal; Morocco.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000400009
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Scorpions and life-history strategies: from evolutionary dynamics toward the scorpionism problem J. Venom. Anim. Toxins incl. Trop. Dis.
Lourenço,Wilson R..
Abstract This work aims to contribute to the general information on scorpion reproductive patterns in general including species that can be noxious to humans. Scorpions are unusual among terrestrial arthropods in several of their life-history traits since in many aspects their reproductive strategies are more similar to those of superior vertebrates than to those of arthropods in general. This communication focuses mainly on the aspects concerning embryonic and post-embryonic developments since these are quite peculiar in scorpions and can be directly connected to the scorpionism problem. As in previous similar contributions, the content of this communication is addressed mainly to non-specialists whose research embraces scorpions in several fields such as...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Reproductive strategies; Embryonic; Postembryonic development.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100206
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Cleaning behaviors in four scorpion species J. Venom. Anim. Toxins incl. Trop. Dis.
Jiao,GB; Zhu,MS.
Scorpions rely predominantly on mechanosensory and chemosensory organs to guide their orientation behaviors. Once sensory organs are affected by the presence of dirt such as clay or prey bodily fluid, scorpions may display a cleaning behavior to reduce or eliminate its influence on their sensory capabilities. In the laboratory, cleaning behaviors of two buthid species, Mesobuthus eupeus (Koch, 1839) and Mesobuthus caucasicus (Nordmann, 1840), and one euscorpiid species, Scorpiops luridus Zhu Lourenço & Qi, 2005 from China, were observed before and after feeding. Moreover, two distinct cleaning behaviors in Scorpiops luridus and three in Heterometrus petersii (Thorell, 1876) (Scorpionidae) were noted for several times during daily activities. Based...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Cleaning behavior; Cleaning means; Prey capture; Daily activity.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200017
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Individual variation in the protein profile of the venom of Mesobuthus gibbosus (Brullé, 1832, Scorpiones: Buthidae) from Turkey J. Venom. Anim. Toxins incl. Trop. Dis.
Ozkan,O; Ciftci,G.
Mesobuthus gibbosus (Brullé, 1832) scorpions were collected from the Mugla province in the Aegean region of Turkey and housed in individual boxes. After extraction, the venom composition was analyzed using gel electrophoresis (SDS-PAGE). Interestingly, all scorpion venom samples contained only one protein band (~68 kDa) in common. Two protein bands (30 and 98 kDa) were common in six venom samples and were absent in the other venoms. Furthermore, two different protein bands (28 and 45 kDa) were detected in seven venom samples. This study proposes possible variations in the composition of individual scorpion venom samples collected from the same geographic region, based on the electrophoretic profile. Additional studies will be necessary in order to assess...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Scorpion; Mesobuthus gibbosus; Venom; Protein; Turkey.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000300017
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Divergences between the Brazilian national information systems for recording deaths from venomous animals J. Venom. Anim. Toxins incl. Trop. Dis.
Bochner,Rosany; Souza,Claudio Mauricio Vieira de.
Abstract Background: This paper aims to highlight and analyze discrepancies in reporting of deaths due to venomous animals in Brazil, from 2001 to 2015, between two national information systems: The Notifiable Diseases Information System (Sistema de Informação de Agravos de Notificação - SINAN) and the Mortality Information System (Sistema de Informações sobre Mortalidade - SIM). Methods: Descriptive and comparative study of the SINAN and SIM information systems, was conducted via the following steps: collecting the death notices from SINAN and SIM; constructing tables and comparative graphics; and, only in scorpion sting fatalities, analyzing the distribution of deaths by age group as described in the specialized literature. Results: While SINAN...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Information system; Death; SINAN; SIM; Snake; Spider; Scorpion; Bee.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100313
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Selection of environmental temperature by the yellow scorpion Tityus serrulatus Lutz & Mello, 1922 (Scorpiones, Buthidae) J. Venom. Anim. Toxins incl. Trop. Dis.
Hoshino,K.; Moura,A. T. V.; De Paula,H. M. G..
The preferred temperature of the yellow scorpion Tityus serrulatus was investigated since its dispersion is a matter of concern. Adult T. serrulatus, weighing 1.24 + 0.20 g (mean + sd) and with a standard length of 59.3 + 2.5 mm, were used. A metallic corridor (120 cm long, 5 cm large and 10 cm high) with thermal gradient ranging from 0°C to 40°C was used. Tityus serrulatus chose and stayed in temperatures ranging from 14°C to 38°C when safe conditions were offered (dark and thigmotactic stimuli). The number of animals that remained in the 11°C-20°C, 21°C-30°C, and 31°C-40°C temperature zones were 8, 8, and 9, respectively. The chi-square test (degree of freedom = 2) showed that differences were not significant (p>0.05). Some animals moved to lower...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tityus serrulatus; Scorpion; Temperature; Thermal gradient; Zoogeography.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000100005
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The evolution and distribution of noxious species of scorpions (Arachnida: Scorpiones) J. Venom. Anim. Toxins incl. Trop. Dis.
Lourenço,Wilson R..
Abstract This contribution attempts to bring some general information on the evolution and, in particular, on the geographic distribution of scorpion species noxious to humans. Since 95% of the scorpions incidents are generated by specimens of the family Buthidae C. L. Koch, the analysis will be limited to this familial group. As in previous similar contributions, the content of this work is mostly addressed to non-specialists whose research embraces scorpions in several fields such as venom toxins and public health. Only in recent years, efforts have been made to create better links between ‘academic scorpion experts’ and other academic non-specialists who use scorpions in their research. Even if a larger progress can yet be expected from such exchanges,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Noxious species; Patterns of distribution; Biased results; Buthidae.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100201
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Optimization of antiscorpion venom production J. Venom. Anim. Toxins incl. Trop. Dis.
Ozkan,O.; Adigüzel,S.; Ates,C.; Bozyigit,I.; Filazi,A..
The present study was carried out to produce highly efficient antivenom from a small number of telsons in a short time. Venom solution was prepared through maceration of telsons from Androctonus crassicauda (Olivier, 1807) collected in the Southeastern Anatolia Region, Turkey. Lethal dose 50% (LD50) of the venom solution injected into mice was 1 ml/kg (95% confidence interval; 0.8-1.3), according to probit analysis. Different adjuvants (Freund's Complete Adjuvant, Freund's Incomplete Adjuvant, and 0.4% aluminium phosphate), at increasing doses and combined with venom, were subcutaneously injected into horses on days 0, 14, 21, 28, 35, and 42 of the experiment. Antivenom was collected from the immunized horses on days 45, 48, and 51 using the pepsin...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Antivenom; Androctonus crassicauda.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000300004
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A study on the genetic diversity of Androctonus crassicauda (Olivier, 1807; Scorpiones: Buthidae) from Turkey J. Venom. Anim. Toxins incl. Trop. Dis.
Ozkan,O; Ahmet,C; Zafer,K.
Mitochondrial DNA (mtDNA) has been widely employed in phylogeographic and phylogenetic studies. In the present study, the genetic identification of the scorpion Androctonus crassicauda (Olivier, 1807) was carried out by using the 16S mitochondrial gene, since this scorpion represents the most important species in Turkey regarding scorpionism and antivenom production. Two genetic groups were found according to the sequence analysis results, while five different loci at the nucleotide level presented genetic variation in the 16S region when compared to a known A. crassicauda sequence data (GenBank, AJ277598). Nucleotide variations found in the current work constitute the first descriptive report for A. crassicauda. Moreover, future studies may enlighten the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Androctonus crassicauda; PCR; Genotype; Turkey.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000400010
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Parametric values of Androctonus crassicauda (Oliver, 1807) (scorpiones: buthidae) from Turkey J. Venom. Anim. Toxins incl. Trop. Dis.
Ozkan,O.; Adiguzel,S.; Kar,S..
The aim of the present study was to analyze the parametric values of Androctonus crassicauda (Oliver, 1807), the most significant scorpion species in Turkey. For this purpose, 11 male and 11 female A. crassicauda specimens were collected from Sanliurfa region. The body parts most important for species identification were measured by using sensitive calipers. Differences between sexes were statistically significant for pectinal organ length (female: 7.50±1.26mm;male: 8.63±1.05mm; p=0.033), pectinal tooth count (female: 25.36±0.86;male: 33.36±0.80; p=0.000), and carapace width (female: 10.27±1.19mm;male: 9.09±0.73mm; p=0.000). However, body length (female: 90.09±14.74mm;male: 82.95±5.40mm), abdomen width (female: 12.09±1.90mm;male: 11.09±0.88mm), and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Androctonus crassicauda; Morphometry; Turkey.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000400003
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The first report of Tityus (Scorpiones: Buthidae) in Anzoátegui State, Venezuela: a new species J. Venom. Anim. Toxins incl. Trop. Dis.
Quiroga,M.; de Sousa,L.; Parrilla-Álvarez,P.; Manzanilla,J..
Tityus gonzalespongai n. sp. is a species endemic to the high mountains of Anzoátegui State, Venezuela. It is found between 1,600 and 2,200 m in ''La Laguna'' mountain. Its habitat includes the area of ''Bosque Húmedo Montano Bajo'' with the type of vegetation of ''Bosque Ombrófilo Montano Siempreverde'' (''Bosques Nublados Costeros'' that includes the ''Subpáramos Arbustivos''). It is distinguished from other Tityus species (T. caripitensis, T. monaguensis, and T. nororientalis) by the following characteristics: 1- the disposition of the trichobothria in the pedipalps; 2- ventral keels of the caudal segments of the metasoma (segment II, double and parallel in the proximal two thirds, then convergent and finally divergent in the base; segments III and IV,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Buthidae; Tityus gonzalespongai; New species; Turimiquire; Anzoátegui; Venezuela.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992004000100003
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Scorpion incidents, misidentification cases and possible implications for the final interpretation of results J. Venom. Anim. Toxins incl. Trop. Dis.
Lourenço,Wilson R..
Abstract The aim of this contribution is to bring general information on the classification and in particular on the specific identification of scorpion species dangerous to humans. Several generic groups are taken into consideration, but the Neotropical genus Tityus C. L. Koch, 1836 is used as a major example. The content of this paper is mostly addressed to non-specialists whose research embraces scorpions in several fields such as venom toxins and public health. Although efforts have been made in the last 20 years to create better links between ‘true scorpion experts’ and non-specialists who use scorpions in their research, such exchanges had never led to a consensus among those different branches of biological and medical research. Consequently, many...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Dangerous species; Misidentification; Biased results; Buthidae; Tityus.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100202
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Anticoagulant and factor Xa-like activities of Tityus discrepans scorpion venom Acta Toxicol. Argent.
Brazón,Josmary; Guerrero,Belsy; Suze,D; Sevcik, Carlos,Gina; Arocha-Piñango,Carmen L.
Tityus discrepans venom (TdV) produces a variety of haemostatic manifestations including alveoli fbrin deposition and/ or prothrombin and partial thromboplastin time (PT, PTT) alterations in mammals. In vitro studies have demonstrated that TdV contains tissue plasminogen activator-like (t-PA), fbrinolytic and plasmin inhibitory compounds and produces platelets activation through GPVI and a novel Src-dependent signalling pathway. The aim of this study is to describe the initial characterization of procoagulant and anticoagulant components from TdV. This venom was fractionated by exclusion molecular chromatography on a Sephadex G-50 column. The eluted material was collected as fve fractions called S1 to S5. These fractions and the whole venom were used to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Coagulation; Fibrinogen; Factor Xa.
Ano: 2013 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432013000100003
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Hematological and biochemical profiles of rats submitted to experimental poisoning with Tityus serrulatus venom Arq. Bras. Med. Vet. Zootec.
Pinto,M.C.L.; Melo,M.M.; Costa,M.E.R.; Labarrere,C.R..
The hematological and biochemical profiles of newly weaned rats submitted to experimental poisoning with T. serrulatus venom were evaluated. Fifteen recently weaned male Wistar rats (mean weight 130g) were distributed into three equal groups (n = 5). Animals in the control group (group A) received a subcutaneous injection of 400μL of ultra-pure water, while those in the experimental groups received, by identical route, 400μL of a solution containing 100μg (group B) or 450μg (group C) of scorpion venom dissolved in ultra-pure water. Red blood cells indexes, and differential leukocyte and total platelet counts were determined, together with levels of serum glucose, urea, creatinine, lactic dehydrogenase, aspartate aminotransferase, amylase, insulin, and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rat; Tityus serrulatus; Scorpion; Experimental envenoming; Hematology; Biochemestry.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352010000200015
Registros recuperados: 38
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