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Registros recuperados: 44
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A new coumarin derivative, 4-acetatecoumarin, with antifungal activity and association study against Aspergillus spp. BJM
Guerra,Felipe Q.S.; Araújo,Rodrigo S.A.; Sousa,Janiere P.; Silva,Viviane A.; Pereira,Fillipe O.; Mendonça-Junior,Francisco J.B.; Barbosa-Filho,José M.; Pereira,Julio Abrantes; Lima,Edeltrudes O..
Abstract Fungal infections have become a concern for health professionals, and the emergence of resistant strains has been reported for all known classes of antifungal drugs. Among the fungi causing disease, we highlight those that belong to the genus Aspergillus. For these reasons, the search for new antifungals is important. This study examines the effects of a coumarin derivative, 4-acetatecoumarin (Cou-UMB16) both alone and together with antifungal drugs, and its mode of action against Aspergillus spp. Cou-UMB16 was tested to evaluate its effects on mycelia growth, and germination of Aspergillus spp. fungal conidia. We investigated its possible action on cell walls, on the cell membrane, and also the capacity of this coumarin derivative to enhance the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coumarin; Antifungal activity; A. flavus; A. fumigatus; Mode of action.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000200407
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Antifungal activity of some Sternbergia taxa: effects on germ tube and biofilm formation BJPS
Kaskatepe,Banu; Yilmaz,Betul Sever; Acikara,Ozlem Bahadir; Iscan,Gulcin Saltan; Vlainic,Josipa; Kosalec,Ivan.
Natural products are rapidly becoming the primary sources of novel antimicrobial agents, as resistance to existing antimicrobial agents is increasing. Apart from determining the antimicrobial activity of natural products, it is also important to understand their effects on the virulence factors of microorganisms. This study aimed to determine the antimicrobial activity of Sternbergia species prevalent in Turkey and investigate their role in the inhibition of germination tube and biofilm formation, both of which are known to be important virulence factors of Candida albicans. The antimicrobial activities of the plant extracts were evaluated using bore-plate and broth microdilution method. The extracts’ capacity to inhibit the formation of the germ-tube was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antifungal activity; Biofilm inhibition; Candida albicans; Germ tube formation; Virulence factor; Sternbergia spp.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100546
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The antifungal effect of six commercial extracts of Chilean propolis on Candida spp Ciencia e Investigación Agraria
Herrera,Christian L; Alvear,Marysol; Barrientos,Leticia; Montenegro,Gloria; Salazar,Luis A.
Propolis has been used in traditional medicine for many centuries because of its benefcial health properties, including its antimicrobial capacity. Prosthesis stomatitis affects a signifcant percentage of users of removable dentures; Candida albicans is the most common fungal species associated with the development of this pathology. Thus, the objectives of this study were: a. To evaluate the antifungal activity of six commercial propolis extracts against Candida spp. that was isolated from the oral cavity of removable dentures users, and b. To determine chemical characteristics of the propolis extracts evaluated. Among the results, we note that these concentrations of polyphenols varied between 9 ± 0.3 and 85 ± 2.1 mg mL-1. Chromatographic analysis was...
Tipo: Journal article Palavras-chave: Antifungal activity; Candida albicans; Propolis.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202010000100007
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The in vitro antifungal evaluation of a commercial extract of Chilean propolis against six fungi of agricultural importance Ciencia e Investigación Agraria
Curifuta,Macarena; Vidal,Jorge; Sánchez-Venegas,Jaime; Contreras,Aliro; Salazar,Luis A; Alvear,Marysol.
Propolis has been used for millennia for its antimicrobial and pharmaceutical properties, whereas its use as an agricultural antifungal agent has only recently been assessed. The chemical characteristics of six ethanolic extracts of Chilean propolis (EEP-1 to EEP-6) were evaluated. The total polyphenols ranged between 7.8 and 42.3 mg mL-1 equivalents of a 2:1 pinocembrin: galangin standard, and the total flavonoid contents ranged between 4.0 and 19.7 mg mL-1 equivalents of quercetin. A high-performance liquid chromatographic (HPLC) analysis allowed the identification of caffeic acid, myricetin, quercetin, kaempferol, apigenin, pinocembrin, galangin, caffeic acid phenethyl ester (CAPE) and rutin. The EEP-3 extract was selected for additional studies based...
Tipo: Journal article Palavras-chave: Alternaria alternata; Antifungal activity; Botrytis cinerea; Flavonoids; Fusarium sp.; Penicillium expansum; Polyphenols; Propolis.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202012000200011
Registros recuperados: 44
Primeira ... 123 ... Última
 

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