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| Registros recuperados: 75 | |
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| Carvalho, Raquel N.; Arukwe, Augustine; Ait-aissa, Selim; Bado-nilles, Anne; Balzamo, Stefania; Baun, Anders; Belkin, Shimshon; Blaha, Ludek; Brion, Francois; Conti, Daniela; Creusot, Nicolas; Essig, Yona; Ferrero, Valentina E. V.; Flander-putrle, Vesna; Furhacker, Maria; Grillari-voglauer, Regina; Hogstrand, Christer; Jonas, Adam; Kharlyngdoh, Joubert B.; Loos, Robert; Lundebye, Anne-katrine; Modig, Carina; Olsson, Per-erik; Pillai, Smitha; Polak, Natasa; Potalivo, Monica; Sanchez, Wilfried; Schifferli, Andrea; Schirmer, Kristin; Sforzini, Susanna; Sturzenbaum, Stephen R.; Softeland, Liv; Turk, Valentina; Viarengo, Aldo; Werner, Inge; Yagur-kroll, Sharon; Zounkova, Radka; Lettieri, Teresa. |
| The risk posed by complex chemical mixtures in the environment to wildlife and humans is increasingly debated, but has been rarely tested under environmentally relevant scenarios. To address this issue, two mixtures of 14 or 19 substances of concern (pesticides, pharmaceuticals, heavy metals, polyaromatic hydrocarbons, a surfactant, and a plasticizer), each present at its safety limit concentration imposed by the European legislation, were prepared and tested for their toxic effects. The effects of the mixtures were assessed in 35 bioassays, based on 11 organisms representing different trophic levels. A consortium of 16 laboratories was involved in performing the bioassays. The mixtures elicited quantifiable toxic effects on some of the test systems... |
| Tipo: Text |
Palavras-chave: Bioassays; Effects; Mixtures; Ecotoxicology; Biomarkers. |
| Ano: 2014 |
URL: https://archimer.ifremer.fr/doc/00499/61115/64667.pdf |
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| Buffet, Pierre-emmanuel; Tankoua, Olivia Fossi; Pan, Jin-fen; Berhanu, Deborah; Herrenknecht, Christine; Poirier, Laurence; Amiard-triquet, Claude; Amiard, Jean-claude; Berard, Jean-baptiste; Risso, Christine; Guibbolini, Marielle; Romeo, Michele; Reip, Paul; Valsami-jones, Eugenia; Mouneyrac, Catherine. |
| Engineered nano-sized Cu oxide particles are extensively used in diverse applications. Because aquatic environments are the ultimate "sink" for all contaminants, it is expected that nanoparticles (NP) will follow the same fate. In this study, two marine invertebrates Scrobicularia plana and Hediste diversicolor were chosen as ecotoxicological models. The aim was to evaluate behavioural (burrowing kinetics, feeding rate) and biochemical (biomarkers) responses of S. plana and H. diversicolor exposed in the laboratory to Cu (10 mu g L(-1)) added in natural seawater either in the form of engineered nanoparticles (NPs) of CuO or as dissolved Cu in 2% HNO(3). Exposure was characterized by considering (i) the physico-chemical fate of NP (ii) the fraction of... |
| Tipo: Text |
Palavras-chave: Copper oxide nanoparticles; Behaviour; Biomarkers; Oxidative stress; Scrobicularia plana; Hediste diversicolor. |
| Ano: 2011 |
URL: http://archimer.ifremer.fr/doc/00040/15140/15856.pdf |
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| Strubbia, Sofia; Lyons, B. P.; Lee, R. J.. |
| Environmental conditions and xenobiotic exposure can be sources of stress to living organisms. Biological markers are measurable indicator of changes which may happen at any biological level and which can be considered an early warning signal of some biological or environmental state or condition. A structured field study was undertaken to investigate the relationship between three biomarker assays and the spatial and temporal variation of each biomarker in samples of Mytilus edulis. The three biomarkers were the neutral red retention assay, micronucleus assay and comet assay, which indicate damage at different cellular/molecular levels. Three sites in Poole Harbour, an area on the South coast of the UK were sampled on six separate occasions at least three... |
| Tipo: Text |
Palavras-chave: Mytilus edulis; Biomarkers; Stress; Neutral red retention; Comet assay; Micronucleus assay; Poole Harbour. |
| Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00481/59274/63447.pdf |
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| Colaco, Ana; Desbruyeres, Daniel; Guezennec, Jean. |
| The polar lipid fatty acid (PLFA) profiles of invertebrates living in chemosynthetic communities can indicate the degree to which these animals depend on specific types of bacteria. To identify the nutritional sources of various species from deep-sea hydrothermal vents of the Mid-Atlantic Ridge, a Principal Component Analysis was performed using individual PLFA profiles as descriptors. Two associations representing different feeding groups were identified: (i) mussels, commensal polychaetes and gastropods, (ii) shrimps and crabs. The first association relies more on sulphide-oxidizing bacteria, while the second one has more anaerobic sulphate-reducing bacteria biomarkers. Other small invertebrates reveal different diets. The polychaete Amathys lutzi shows... |
| Tipo: Text |
Palavras-chave: Mid Atlantic Ridge; Biomarkers; Hydrothermal vents; Fatty acids. |
| Ano: 2007 |
URL: http://archimer.ifremer.fr/doc/2007/publication-2538.pdf |
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| Mckenzie, David; Axelsson, Michael; Chabot, Denis; Claireaux, Guy; Cooke, Steven J.; Corner, Richard A.; De Boeck, Gudrun; Domenici, Paolo; Guerreiro, Pedro M.; Hamer, Bojan; Jorgensen, Christian; Killen, Shaun S.; Lefevre, Sjannie; Marras, Stefano; Michaelidis, Basile; Nilsson, Goran E.; Peck, Myron A.; Perez-ruzafa, Angel; Rijnsdorp, Adriaan D.; Shiels, Holly A.; Steffensen, John F.; Svendsen, Jon C.; Svendsen, Morten B. S.; Teal, Lorna R.; Van Der Meer, Jaap; Wang, Tobias; Wilson, Jonathan M.; Wilson, Rod W.; Metcalfe, Julian D.. |
| The state of the art of research on the environmental physiology of marine fishes is reviewed from the perspective of how it can contribute to conservation of biodiversity and fishery resources. A major constraint to application of physiological knowledge for conservation of marine fishes is the limited knowledge base; international collaboration is needed to study the environmental physiology of a wider range of species. Multifactorial field and laboratory studies on biomarkers hold promise to relate ecophysiology directly to habitat quality and population status. The 'Fry paradigm' could have broad applications for conservation physiology research if it provides a universal mechanism to link physiological function with ecological performance and... |
| Tipo: Text |
Palavras-chave: Biomarkers; Ecological models; Fisheries; Fry paradigm; Individual variation; Telemetry. |
| Ano: 2016 |
URL: https://archimer.ifremer.fr/doc/00616/72841/72999.pdf |
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| Berge, Jean-pascal; Barnathan, Gilles. |
| Because of their characteristic living environments, marine organisms produce a variety of lipids. Fatty acids constitute the essential part of triglycerides and wax esters, which are the major components of fats and oils. Nevertheless, phospholipids and glycolipids have considerable importance and will be taken into account, especially the latter compounds that excite increasing interest regarding their promising biological activities. Thus, in addition to the major polyunsaturated fatty acids (PUFA) such as eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, a great number of various fatty acids occur in marine organisms, e.g. saturated, mono- and diunsaturated, branched, halogenated, hydroxylated, methoxylated, non-methylene-interrupted. Various... |
| Tipo: Text |
Palavras-chave: Nutrition; Biomarkers; Marine organisms; Fatty acids; Lipids. |
| Ano: 2005 |
URL: http://archimer.ifremer.fr/doc/2005/publication-937.pdf |
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| TAWFEEQ, Mohammad Monir; HORIUCHI, Noriyuki; KOBAYASHI, Yoshiyasu; FURUOKA, Hidefumi; INOKUMA, Hisashi; 堀内, 雅之; 古林, 与志安; 古岡, 秀文; 猪熊, 壽. |
| Expression of six selective genes in peripheral blood cells was evaluated as diagnostic biomarkers for enzootic bovine leukosis (EBL) by using 10 EBL and 15 clinically healthy cattle. The clinically healthy cattle generally showed lower gene expression levels. Although wide variations of gene expression were found in some clinical cases of EBL, 4 and 5 among 10 EBL cattle showed higher expression of interleukin 2 receptor gene (IL2R) and Wilms’ tumor gene (WT1), respectively. Expression of IL2R in peripheral blood cells in EBL cattle was statistically increased; however, the lower sensitivity and higher variation in the gene expressions among clinical cases of EBL would be problems as diagnostic biomarkers. |
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Palavras-chave: Biomarkers; Enzootic bovine leukosis; Gene expression; QRT-PCR. |
| Ano: 2013 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3868 |
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| Uribe, P.. |
| En la Antártica se ha descrito un grupo de microalgas (diatomeas bentónicas), que viven en el fondo, pegadas a las piedras o sedimentos, capaces de hacer fotosíntesis con niveles de luz muy bajos e incluso cubiertas por una capa de hielo marino. El proyecto “Identificación de biomarcadores de fluctuaciones de la cobertura de hielo en diatomeas bentónicas de la Península Antártica” busca conocer las características fisiológicas que determinan la adaptación de estas microalgas al medio polar, características que luego sirvan como marcadores biológicos (o biomarcadores) de esta capacidad de vivir en las zonas más oscuras. Paulina Uribe describe este proyecto y establece un curioso vínculo con las ideas y circunstancias de Darwin. |
| Tipo: Journal Contribution |
Palavras-chave: Algae; Biomarkers; Benthos; Benthos; Algae; Http://aims.fao.org/aos/agrovoc/c_878; Http://aims.fao.org/aos/agrovoc/c_258. |
| Ano: 2009 |
URL: http://hdl.handle.net/1834/3366 |
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| CRUZ,C.; SILVA,A.F.; SHIOGIRI,N.S.; GARLICH,N.; PITELLI,R.A.. |
| the aims of this study were to determine imazapyr efficacy for floating macrophyte control and ecotoxicology for non-target organisms. For the floating macrophyte control efficacy tests were used the doses of 0,5; 1,0; 2,0; 2,5; 3,0; 3,5 and 4,0 L ha-1 and a control with 10 replicates. The acute toxicology for non-target organisms was estimated by lethal concentration 50% (LC50 and EC50). The floating macrophyte control efficacy was over 90%. Imazapyr was classified as moderately toxic for the following biomarkers: L. minor, H. eques, B. rerio, P. caudimaculatus, P. canaliculata, and P. mesopotamicus and lightly toxic for A. caroliniana. Thus, imazapyr herbicide is a tool with great potential to be used on floating macrophyte control (E. crassipes, P.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acute toxicology; Biomarkers; Aquatic plants management. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582015000100103 |
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| CHAVES,Valesca de Souza; MARCON,Jaydione Luiz; DUNCAN,Wallice Paxiúba; ALVES-GOMES,José Antônio. |
| ABSTRACT Deltamethrin is a pyrethroid insecticide widely used in pest control in Brazilian agriculture. The intensive and disordered use of this pesticide in the Amazon region can drive it into aquatic ecosystems in several ways, but mainly by runoff and leaching. The present study was conceived to determine the acute toxicity (LC50) of a deltamethrin based pesticide (DBP) and to characterize its effects on two biochemical biomarkers, glutathione-S-transferase (GST) and acetylcholinesterase (AChE), in tissues of the electric fish Microsternarchus cf. bilineatus. Fishes were exposed to concentrations of 1, 2, 3, 4 and 5 μg L-1 of DBP for up to 96 hours. For each treatment, the absolute activity of the enzymes GST (muscle and liver) and AChE (muscle and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pyrethroid insecticide; Biomarkers; Median LC50; Glutathione-S-transferase; Acetylcholinesterase. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672020000400355 |
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| Montes, Caroline da Silva; UFPR; Ferreira, Maria Auxiliadora Pantoja; UFPR; Santos, Simone do Socorro Damasceno; UFPR; Ledebur, Esther Iris C. Freifrau Von; UFPR; Rocha, Rossineide Martins; UFPR. |
| This work analyzes the morphological alterations in Brachyplatystoma rousseauxii gills and evaluates whether this species can be considered an environmental monitoring biomarker of Guajará Bay. Sampling was carried out in four areas around Belém, Brazil, in four annual periods: dry/wet season, wet season, wet/dry season and dry season. Water pH, temperature and suspended material were evaluated. A total of 36 specimens were collected. The second right gill arch of each animal was removed and immediately fixed and processed for histopathology analysis with light microscopy. The physicochemical analysis of the water during the study period showed slight acidity, temperature and material in suspension within normal levels. Histopathological analysis of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biomarkers; Environmental monitoring; Histological alterations; Fish Morfologia biomarkers; Environmental monitoring; Histological alterations; Fish Histologia. |
| Ano: 2009 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/4800 |
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| Silva,Cesar A.; Madureira,Luiz A.S.. |
| The relative distribution of several compounds identified in four samples of recently deposited sediments of the Itacorubi Mangrove located on the Santa Catarina Island, southern Brazil, was compared with similar data on compounds extracted from fresh leaves of three mangrove species (Avicennia schaueriana, the dominant species in the area, Rhizophora mangle and Laguncularia racemosa) and the Gramineae Spartinna alterniflora. Terpenols, previously identified in mangrove species in northern Brazil, were also found. A. schaueriana mainly contains β-amyrin (90.6 μg g-1 of extractable organic matter); low amounts of friedelin, betulin and germanicol were detected only in the leaf extract of this species. R. mangle also contained a significant amount of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biomarkers; Leaf; Mangrove; Santa Catarina; Sediment. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000300002 |
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| Montanha,F.P.; Fredianelli,A.C.; Wagner,R.; Sacco,S.R.; Rocha,D.C.C.; Pimpão,C.T.. |
| The acute intoxication of Cypermethrin in Silver Catfish (Rhamdia quelen) was evaluated. Animals weighing 56.67±4.43g and measuring 18.92±1.16cm were exposed to sublethal concentrations of Cypermethrin for the species in hydrological conditions during 96 hours. A total of 52 fish divided into three groups were used and received the following concentrations of Cypermethrin: 0 (n=12); 1.5 (n=20) and 2.5 (n=20)mg/L. The intoxicated animals suffered behavioral changes such as loss of balance, swimming alteration, dyspnea, upright swimming and sudden spiral swimming movements. As soon as the 96-hour period was over, a blood collection for hematological and biochemical analyses was performed. A complete haemogram test, plasmatic protein test, albumin, alanine... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fish; Biomarkers; Ecotoxicology; Haemogram; Pyrethroids. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000300697 |
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| Adonis,Marta I; Díaz,Jose; Miranda,Veronica R; Chahuan,Marco; Zambrano,Alcides; Benitez,Hugo C; Campos,Monica; Avaria,Pablo; Urzúa,Ulises; Marín,Pedro; Gohurdett,Mariela; Cisterna,Yasna; Gil,Lionel. |
| BACKGROUND: The mortality of lung cancer (LC), increases each year in the world, in spite of any advances, in development of new drugs to advance stages of LC. The high incidence of LC has been associated with smoking habit, genetic diversity and environmental pollution. Antofagasta region has been reported to have the highest LC mortality rate in Chile and its inhabitants were exposed to arsenic in their drinking water in concentrations as high as 870 μg/L. Non-invasive techniques such as biomarkers (Automatic Quantitative Cytometry: AQC and DR70) and Auto Fluorescence Bronchoscopy (AFB) might be potentially useful as a supplementary diagnostic approach and early detection. Early detection is one of the most important factors to intervene and... |
| Tipo: Journal article |
Palavras-chave: Early detection; Biomarkers; Lung cancer. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100056 |
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| Abessa,Denis Moledo de Souza; Zaroni,Letícia Pires; Sousa,Eduinetty Ceci Pereira Moreira de; Gasparro,Marcia Regina; Pereira,Camilo Dias Seabra; Rachid,Bauer Rodarte de Figueredo; Depledge,Michael; King,Rebecca Susan. |
| The physiological conditions of mussels from Ubatuba and Santos and also of organisms transplanted from Ubatuba to Santos were studied by using different techniques. Assays for lysosomal stability were conducted on the haemolymph. Heart rate activity was monitored for 6h. The embryonic development of larvae obtained from the collected mussels was analysed. For all the compared groups of mussels, no significant differences were observed for the cardiac activity monitoring and the embryonic bioassays. The mean Neutral Red (NR) retention time was similar for the animals from Santos and Ubatuba, whereas the organisms transplanted to Santos showed a reduction in the retention time of the dye, indicating damage in the lysosomal membranes. These differences were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Perna perna; Neutral red retention assay; Capmon system; Embryonic assay; Biomarkers; Physiology. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000200008 |
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| Dalzochio,Thaís; Souza,Mateus Santos de; Simões,Leonardo Airton Ressel; Silva,Gláucia Joselaine Herbert; Rodrigues,Gabriela Zimmermann Prado; Andriguetti,Natália Bordin; Silva,Luciano Basso da; Gehlen,Günther. |
| Abstract: The Paranhana River, located in Southern Brazil, is one of the major tributaries of the Sinos River basin and receives mainly industrial and domestic effluents. In the present study, water physicochemical and microbiological analyses, condition factor, micronucleus test, gill histopathology and metal bioaccumulation in the muscle of the native fish Bryconamericus iheringii collected at two sites (S1 and S2) of the Paranhana River under different degrees of anthropogenic pressures were assessed in four sampling campaigns. Data from water quality parameters, condition factor, mucous cells proliferation in fish gills and bioaccumulation of chromium and manganese in muscle evidenced higher impacts at S2, whereas a higher genotoxic potential was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biomarkers; Paranhana River; Bioaccumulation; Histopathology; Micronucleus. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100421 |
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| Amaral,Ademir. |
| Biological dosimetry (biodosimetry) is based on investigations of induced biological effects (biomarkers) in order to correlate them with radiation dose. Among the indicators employed in biodosimetry, scoring of chromosome aberrations is the most reliable method to quantify individual exposure to ionizing radiation. The technique, applied to circulating lymphocytes, has been developed into a routine procedure to evaluate the dose in the case of real or suspected accidental exposure. Considering the radiosensitivity of lymphocytes in vitro and in vivo as being the same, the dose effect relationship obtained after in vitro irradiation of blood has been widely used, with medico-legal value, for evaluating individual radiation exposure. This report presents an... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biodosimetry; Physical dosimetry; Biomarkers; Chromosome aberrations. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500017 |
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| Registros recuperados: 75 | |
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