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| Registros recuperados: 46 | |
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| Glavic,Alvaro; López-Varea,Ana; de Celis,José F. |
| The Notch signaling pathway plays an important role in development and physiology. In Drosophila, Notch is activated by its Delta or Serrate ligands, depending in part on the sugar modifications present in its extracellular domain. O-fucosyltransferase-1 (OFUT1) performs the first glycosylation step in this process, O-fucosylating various EGF repeats at the Notch extracellular domain. Besides its O-fucosyltransferase activity, OFUT1 also behaves as a chaperone during Notch synthesis and is able to down regulate Notch by enhancing its endocytosis and degradation. We have reevaluated the roles that O-fucosylation and the synthesis of GDP-fucose play in the regulation of Notch protein stability. Using mutants and the UAS/Gal4 system, we modified in developing... |
| Tipo: Journal article |
Palavras-chave: Notch; GMD; O-fucosyltranserase; Drosophila. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000100004 |
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| Mata,Renata Alves da; Roque,Francisco; Tidon,Rosana. |
| The Paranã Valley, located in the Central Brazil Plateau, within the domain of the Cerrado biome, is frequently cited as a center of endemism and diversity. Nonetheless, this region is poorly known, mainly considering its invertebrate fauna. Here, drosophilid flies were used as biological tools to contribute to a broader inventory, whose goals were mapping the Cerrado biodiversity and identifying areas to be conserved. Three previously unsampled areas in the Paranã Valley were sampled. Amongst the 12,297 specimens collected 45 species were identified, which represents 50% of the drosophilid species previously recorded in the Cerrado. Moreover, this sampling presented eight new occurrences for the biome (Drosophila annulosa, D. calloptera, D. papei, D.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biodiversity; Brazilian savanna; Central Brazil Plateau; Conservation; Drosophila; Inventory. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-06032008000100006 |
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| Lopes,E.S.S.; Araujo,H.M.. |
| Activation of NFkappaB plays a pivotal role in many cellular processes such as inflammation, proliferation and apoptosis. In Drosophila, nuclear translocation of the NFkappaB-related transcription factor Dorsal is spatially regulated in order to subdivide the embryo into three primary dorsal-ventral (DV) domains: the ventral presumptive mesoderm, the lateral neuroectoderm and the dorsal ectoderm. Ventral activation of the Toll receptor induces degradation of the IkappaB-related inhibitor Cactus, liberating Dorsal for nuclear translocation. In addition, other pathways have been suggested to regulate Dorsal. Signaling through the maternal BMP member Decapentaplegic (Dpp) inhibits Dorsal translocation along a pathway parallel to and independent of Toll. In... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: JAK kinase; Drosophila; Embryonic patterning; Hopscotch; NFkappaB. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001200006 |
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| Pimenta,Raphael S.; Alves,Priscila D. D.; Almeida,Gabriel M. F.; Silva,Juliana F.M; Morais,Paula B.; Corrêa Jr.,Ary; Rosa,Carlos A.. |
| We studied the yeast communities associated with fruits, mushrooms, tree exudates, and flies of the genus Drosophila, in two Atlantic Rain Forest fragments in state of Minas Gerais, Brazil. A total of 456 samples were collected from Rio Doce State Park and 142 from Ecological Station of Universidade Federal de Minas Gerais. From these samples, 608 yeast isolates were obtained, belonging to 71 different species. Among the yeasts isolated from Rio Doce State Park, 17 isolates were recovered from fruits, 12 from mushrooms, 13 from tree exudates, and 299 from Drosophila spp. In the Ecological Station of Universidade Federal de Minas Gerais, 24 isolates were recovered from fruits and 243 from Drosophila spp. Distinct communities of yeast were observed in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Yeast communities; Drosophila; Fruits; Mushrooms; Tree exudates; Atlantic Rain Forests. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000100015 |
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| Registros recuperados: 46 | |
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