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The effect of drought and subsequent precipitation pulse on productivity, species composition, and carbon fluxes of the herbaceous understorey in a cork oak woodland Nature Precedings
Marjan Jongen; Maria C. Caldeira; João S. Pereira.
In the Iberian Peninsula, the cork oak woodlands are of great ecological and socio-economic importance. These savanna-type woodlands are characterized by an herbaceous understorey, dominated by C3 annual species. The productivity and related ecosystem processes of this understorey are highly dependent on timing and magnitude of precipitation events. 

Climate change scenarios for the Iberian Peninsula suggest not only increasing air temperatures, but also the possibility of decreasing spring precipitation, accompanied by an increase in the interval between precipitation events, which might cause drought conditions to occur, with more severe effects on productivity and ecosystem processes....
Tipo: Presentation Palavras-chave: Ecology.
Ano: 2009 URL: http://precedings.nature.com/documents/3706/version/1
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Cognitive deficits of schizophrenia: the flower workshop initiative Nature Precedings
Maria Alice Ornellas Pereira; Alfredo Pereira Jr.
Advancement of research on the neurobiology of the schizophrenic brain has revealed a complex of factors, from genetic tendencies affecting the development of brain structure to functional impairment caused by defective molecular signaling. Recently, the attention of psychiatrists and mental health professionals has been directed to the presence of cognitive deficits, responsible for most of the obstacles to the social insertion of patients.The schizophrenic person has a difficulty to manage the flux of consciousness in social interactions. We address this difficulty with the Flower Arrangement Workshop, a methodology of Psycho-Social Rehabilitation that reduces the vulnerability of the schizophrenic in the social environment. The workshop was offered...
Tipo: Presentation Palavras-chave: Neuroscience.
Ano: 2008 URL: http://precedings.nature.com/documents/1497/version/1
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Identification of transcription regulation associated proteins in plants and stramenopiles Nature Precedings
Diego Mauricio Riaño Pachón; Silvia Restrepo; Bernd Mueller-Roeber; Francisco Buitrago Florez.
The generation of biodiversity is tied to the evolution and re-wiring of gene regulatory networks (GRNs). One component of these GRN are transcription factors and other transcriptional regulators. We have devised a pipeline for the identification of TFs and TRs, exploiting the domain architecture of these proteins. Currently we have a set of rules, representing 138 proteins families, that we have applied to the identification of ~20 different plant species and several species of Stramenopiles, where important plant pathogens are found. Results for plant species are available at http://plntfdb.uniandes.edu.co/; we are now developing a newer interface for Stramenopiles.
Tipo: Presentation Palavras-chave: Bioinformatics; Evolutionary Biology.
Ano: 2012 URL: http://precedings.nature.com/documents/7000/version/1
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Emerging Trends of Nanotechnology towards Picotechnology: Energy and Biomolecules Nature Precedings
Rakesh Sharma; Avdhesh Sharma; Ching J. Chen.
In nature, metal oxide particles display their existence at the level of picomolecules in solution state and bioactive states in the body. We present evidence of picomolar behavior of molecules different than nanomolar behavior of particles. These particles can be encapsulated in polymers and can be functionalized with protein, nucleotides, and drugs to develop as smart intracellular targeting pico-devices. The preparation technique and physiological conditions decide the size and functionality of these pico-carrier devices. Their usable success rate, feasibility and potentials are yet to be proven or we do not know. The major difference between nanodevices and pico-devices is their intermolecular and intramolecular thermodynamics in medium and their...
Tipo: Presentation Palavras-chave: Biotechnology; Chemistry.
Ano: 2010 URL: http://precedings.nature.com/documents/4525/version/1
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Capturing lost research Nature Precedings
Rebecca Lawrence.
A very significant proportion of valuable research conducted is lost, either after presentation at a meeting or even at the stage of the creation of the initial dataset; _F1000 Posters_ and _F1000 Research_ aim to capture this valuable information.
Tipo: Presentation Palavras-chave: Bioinformatics.
Ano: 2011 URL: http://precedings.nature.com/documents/6175/version/1
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Specificity and Evolvability in Eukaryotic Protein Interaction Networks Nature Precedings
Pedro Beltrao; Luis Serrano.
Progress in uncovering the protein interaction networks of several species has led to questions of what underlying principles might govern their organization. Few studies have tried to determine the impact of protein interaction network evolution on the observed physiological differences between species. Using comparative genomics and structural information, we show here that eukaryotic species have rewired their interactomes at a fast rate of approximately 10?5 interactions changed per protein pair, per million years of divergence. For Homo sapiens this corresponds to 103 interactions changed per million years. Additionally we find that the specificity of binding strongly determines the interaction turnover and that different biological processes show...
Tipo: Presentation Palavras-chave: Bioinformatics; Evolutionary Biology.
Ano: 2007 URL: http://precedings.nature.com/documents/26/version/1
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Patterns in soil ammonia-oxidizer response to global change Nature Precedings
Kathryn M. Docherty; Brendan Bohannan; Audrey Niboyet; Xavier LeRoux.
Background/Question/Methods
The Domains Archaea and Bacteria contain the vast majority of Earth’s biodiversity and biomass, and their members play critical, often exclusive, roles in many biogeochemical cycles and ecosystem services. Human-induced global change, particularly with respect to increased nitrogen deposition, has the potential to drastically alter how soil nitrifying communities perform their biogeochemical function. Additionally, multi-factor global change can alter how microbial communities interact with each other and with the associated plant communities. This study, performed in the context of the long-term Jasper Ridge Global Change Experiment (JRGCE) in a California grassland ecosystem, examines how...
Tipo: Presentation Palavras-chave: Ecology; Microbiology; Earth & Environment.
Ano: 2011 URL: http://precedings.nature.com/documents/5508/version/1
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Little cost of injury to growth and development of damselflies Nature Precedings
Timothy M. Sesterhenn; Philip H. Crowley.
*_Background:_*
Damaged or missing appendages are a common problem in numerous vertebrate and invertebrate taxa and can negatively affect many aspects of life: mobility, foraging, predator avoidance, growth, and development have all been shown to suffer. Many animals use autotomy to survive a predation attempt but suffer diminished performance until the missing appendage heals or regenerates. Animals that regenerate face an extra problem, as they must re-allocate resources away from growth and development in order to regrow their missing parts. We examined the effect of appendage loss on the growth and development of the damselfly Ischnura posita. Damselfly larvae have three caudal lamellae, external gills that can be autotomized and...
Tipo: Presentation Palavras-chave: Ecology.
Ano: 2009 URL: http://precedings.nature.com/documents/3612/version/1
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The Networked Naturalist: Mobile phone data collection for citizen science and education Nature Precedings
Eric Graham.
*Background/Question/Methods*
Citizen science projects engage individual volunteers or groups to observe, measure, and contribute data to scientific studies. CENS is building a collection of mobile phone and web-based tools to make the citizen scientist experience more engaging and flexible. CENS is an NSF-funded Information and Technology Center that employs graduate students from Computer Science and Electrical Engineering at UCLA to create open-source software that is environmentally and socially responsible. The overarching goal of the Networked Naturalist project is to enhance participatory learning experiences through citizen science campaigns and help transform the associated learning process. We are collaborating with national...
Tipo: Presentation Palavras-chave: Ecology.
Ano: 2010 URL: http://precedings.nature.com/documents/5198/version/1
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Overview of BioSharing Nature Precedings
Susanna-Assunta Sansone.
Research communities, funding agencies, and journals participate in the development of reporting standards for the bioscience domain to ensure that shared experiments are reported with enough information to be comprehensible and (in principle) reproducible, compared or integrated (Field, Sansone et al., Science, 2009). Similar trends in both the regulatory arena and commercial science.

Proliferation of standards is a positive sign of stakeholders’ engagement, but how much do we know about these standards? Which ones are mature and stable enough to use or recommend? Which tools and databases implement which standard? Etc...

The BioSharing catalogue (www.biosharing.org) aims...
Tipo: Presentation Palavras-chave: Bioinformatics; Data Standards.
Ano: 2011 URL: http://precedings.nature.com/documents/6151/version/1
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Commonness and rarity of species: Does species' rank influence contribution to ecosystem function? Nature Precedings
Meha Jain; Case Prager; Dan Flynn; Caroline Devan; Georgia Hart; Farshid Ahrestani; Dan Bunker; Matt Palmer; Sean Smukler; Jason Sircely; Shahid Naeem.
Across the globe, biodiversity loss is occurring at an unprecedented rate. Rare species are especially susceptible to extinction, given that they typically have small population sizes and restricted geographic ranges, are less adaptable to disturbances, and are greater habitat specialists. However, while rare species may be prone to extinction, it remains unclear whether the loss of rare species is important to ecosystem function. In addition, it is important to consider the way in which rarity is defined, given that there are multiple definitions of rarity based on a species' geographic range, habitat specificity, and abundance in a community. Therefore, to better understand the contribution of rare species to community function, our study has...
Tipo: Presentation Palavras-chave: Ecology.
Ano: 2010 URL: http://precedings.nature.com/documents/5243/version/1
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Finding Bicliques in Digraphs: Application into Viral-host Protein Interactome Nature Precedings
Malay Bhattacharyya; Sanghamitra Bandyopadhyay; Ujjwal Maulik.
We provide the first formalization true to the best of our knowledge to the problem of finding bicliques in a directed graph. The problem is addressed employing a two-stage approach based on an existing biclustering algorithm. This novel problem is useful in several biological applications of which we focus only on analyzing the viral-host protein interaction graphs. Strong and significant bicliques of HIV-1 and human proteins are derived using the proposed methodology, which provides insights into some novel regulatory functionalities in case of the acute immunodeficiency syndrome in human.
Tipo: Presentation Palavras-chave: Immunology; Bioinformatics.
Ano: 2012 URL: http://precedings.nature.com/documents/7148/version/1
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OntoFox: Nature Precedings
Zuoshuang Xiang; Yongqun He.
OntoFox ("http://ontofox.hegroup.org/":http://ontofox.hegroup.org/) is a web server that facilitates ontology development by automatically fetching ontology terms and their annotations from existing ontologies and saving the results in importable RDF/OWL format. OntoFox is developed based on the MIREOT principle. Currently OntoFox can fetch ontology annotations from >10 existing ontologies. OntoFox provides an efficient approach to promote ontology sharing and interoperability.
Tipo: Presentation Palavras-chave: Bioinformatics.
Ano: 2009 URL: http://precedings.nature.com/documents/3528/version/1
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Integration of microbial communities into large-scale ecosystem models Nature Precedings
Steven D. Allison.
*Background/Question/Methods*
Micro-organisms, including Bacteria, Archaea, and Fungi, control major processes throughout the Earth system. Recent advances in microbial ecology and microbiology have revealed an astounding level of genetic and metabolic diversity in microbial communities. However, a framework for interpreting the meaning of this diversity has lagged behind the initial discoveries. Microbial communities have yet to be included explicitly in any major biogeochemical models in terrestrial ecosystems, and have only recently broken into ocean models. Although simplification of microbial communities is essential in complex systems, omission of community parameters may seriously compromise model predictions of biogeochemical...
Tipo: Presentation Palavras-chave: Ecology; Earth & Environment.
Ano: 2009 URL: http://precedings.nature.com/documents/3633/version/1
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The Gene Ontology's Reference Genome Project: A Unified Framework for Functional Annotation across Species Nature Precedings
Pascale Gaudet; Reference Genome Group.
Complete functional annotation of genomes is a powerful tool for researchers; however, such annotation is a time-consuming task limited by the availability of experimental data. The function of genes for which there is no experimental data can often be predicted via comparison to related, annotated sequences of known function. We describe here the Reference Genome project, an effort from the Gene Ontology (GO) Consortium to fully annotate twelve genomes to rigorous standards: human, plus eleven organisms that are important models in biomedical research, including mouse, fly, zebrafish, yeast and _E. coli_. To achieve this, we examine existing experimentally based annotations in a phylogenetic context in order to infer the function(s) of ancestral proteins...
Tipo: Presentation Palavras-chave: Genetics & Genomics; Bioinformatics.
Ano: 2009 URL: http://precedings.nature.com/documents/3150/version/1
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Changes in Scholarly Communication and the Potential Impact on Biocuration Nature Precedings
Philip Bourne.
Open access in particular and changes in on-line scholarship have the potential to impact biocuration which often involves translating information currently read in papers to knowledge that is found in a variety of biological resources. The implication of these changes in scholarly communication to the biocuration process will be discussed with references to our work and that of others.

Tipo: Presentation Palavras-chave: Genetics & Genomics; Molecular Cell Biology; Bioinformatics.
Ano: 2009 URL: http://precedings.nature.com/documents/3229/version/1
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Progress report: SBML Level 3 package FBA Nature Precedings
Brett G. Olivier; Frank T. Bergmann.
The SBML Level 3 "FBA" package is a proposal for an extension to the current Level 3 Core specification that allows for the description and annotation of constraint based models.

This allows one to e.g. store information related to flux balance analysis in SBML Level 3 models.
Tipo: Presentation Palavras-chave: Bioinformatics; Data Standards.
Ano: 2010 URL: http://precedings.nature.com/documents/5033/version/1
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Overcoming the Ontology Enrichment Bottleneck with Quick Term Templates Nature Precedings
Bjoern Peters; Alan Ruttenberg; Jason Greenbaum; Melanie Courtot; Ryan Brinkman; Patricia Whetzel; Daniel Schober; Susanna Assunta Sansone; Richard Scheuerman; Philippe Rocca-Serra.
The developers of the Ontology of Biomedical Investigations (OBI) primarily use Protégé for editing. However, adding many classes with similar patterns of logical definition is time consuming, error prone, and requires the editor to have some expertise in OWL. Therefore, the process is poorly suited for a large number of domain experts who have limited experience Protégé and ontology development. We have developed a procedure to ease this task and allow such domain experts to add terms to the ontology in a way that both effectively includes complex logical definitions yet requires minimal manual intervention by OBI developers. The procedure is based on editing a Quick Term Template in a spreadsheet format which is...
Tipo: Presentation Palavras-chave: Bioinformatics.
Ano: 2009 URL: http://precedings.nature.com/documents/3970/version/1
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Hierarchical Model Composition updates Nature Precedings
Lucian Smith.
A summary of the status of the hierarchical model composition package for SBML Level 3, and of its current implementation.
Tipo: Presentation Palavras-chave: Bioinformatics; Data Standards.
Ano: 2011 URL: http://precedings.nature.com/documents/6402/version/1
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1. MIRIAM Identifiers and Resources / 2. Existing Identifier Schemes Nature Precedings
Nick Juty; Camille Laibe; Nicolas Le Novere.
(1) An overview of the MIRIAM identifier scheme is presented, together with a description of the supporting tools and resources which allow its use as a robust cross-referencing framework.
(2) An overview of existing identifier schemes within the life sciences is presented, describing the status of each scheme, the prerequisites that a user must meet to use them, and their limitations.
Tipo: Presentation Palavras-chave: Data Standards.
Ano: 2011 URL: http://precedings.nature.com/documents/6154/version/1
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