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| Registros recuperados: 134 | |
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| Chattopadhyay,Rabi Ranjan; Bhattacharyya,Subir Kumar; Medda,Chiranjib; Chanda,Sunanda; Bag,Anwesa. |
| A comparative in vitro antibacterial potential of extracts (aqueous and ethanol) of five important medicinal plants (Aegle marmelos, Azadirachta indica, Terminalia chebula, Mangifera indica and Ocimum sanctum) were investigated using microbial growth inhibition assays against the common human pathogenic bacteria (Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli) of clinical origin. All the plant materials showed varying degrees of strain specific inhibitory action and ethanol extract of the plant materials showed higher antibacterial activity than their aqueous counterparts. Besides, T. chebula and A. marmelos had the strongest antibacterial activity out of which, T. chebula possessed a wider spectrum and a superior antibacterial... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pathogenic bacteria; Medicinal plants; Antibacterial potential; Comparative study. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000500009 |
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| Cordeiro,Yonara de Gouveia; Rochetti,Arina Lázaro; Souza,Vinicius Castro; Silva,Edson Roberto da; Scatolini,Antônio Márcio; Genovese,Maria Inés; Yasui,George Shigueki; Fukumasu,Heidge. |
| Abstract Lafoensia pacari A. St. Hill has been used in traditional medicine as an anti-ulcerogenic and anti-inflammatory. Although there is an ethnopharmacological indication for cancer treatment, only a few studies have demonstrated its possible anticancer activity. Thus, the aims of this study were: (1) to evaluate the antineoplastic effect of L. pacari ethanolic extract (LPE) in lung carcinoma cells, (2) to determine the mode of action of LPE and (3) to identify the substances present in LPE. Human and murine lung cancer cell lines were grown in vitro and treated with different concentrations of LPE. Cell cycle and caspase-3 activity assays were performed in order to verify the mode of action. LC-ESI-MS screening was performed to detect the compounds... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antineoplastic effect; Cell cytotoxicity; Medicinal plants; Procyanidins. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100302 |
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| Monteiro,Juliana Castro; Matta,Sérgio Luis Pinto da; Predes,Fabrícia de Souza; Oliveira,Tânia Toledo de. |
| Rudgea viburnoides leaves are widely used in popular Brazilian medicine as a diuretic, antirheumatic, hypotensive and blood depurative tea. The present study was carried out to investigate the effects of this infusion on the liver and on the plasma biochemical parameters of Wistar rats. Two groups received the R. viburnoides leaf infusion at a daily dose of 10 or 20g dry-leaves/L water, during 40 days. The histopathological analysis did not show degenerated areas or infiltration of leucocytes. Hepatic morphometry showed accumulation of fat in the hepatocytes of the treated groups. There was no significant change in the plasma levels of urea, creatinin, uric acid, direct bilirubin, cholesterol, total proteins, albumin, gamma glutamyl tranferase (gamma-GT),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Congonha-de-bugre; Rubiaceae; Medicinal plants. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200018 |
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| Benvenutti,Régis Carlos; Gomes,Denise B.; Zanchet,Barbara; Locateli,Gelvani; Vechia,Cristian Alex Dalla; Zanotelli Serpa,Patrícia; Lutinski,Junir; Rodrigues Junior,Sinval Adalberto; Schönell,Amanda Patrícia; Diel,Kriptsan Abdon Poletto; Miorando,Daniela; Ernetti,Jackeline; Alves,Bianca de Oliveira; Zilli,Gabriela Adriany Lisboa; Banzato,Thais Petrochelli; Ruiz,Ana Lúcia Tasca Gois; Vidal Gutiérrez,Max; Vilegas,Wagner; Roman Junior,Walter Antônio. |
| Abstract Natural products, especially phytochemicals, have been extensively studies and have exhibited important antiproliferative effects. The American native species Urera baccifera (L.) Gaudich. ex Wedd. (Urticaceae) is widely distributed in Brazil, where it is known as urtiga-vermelha or urtigão. The leaves are popularly used as anti-inflammatory, antirheumatic and in the treatment of gastric disorders. However, the antiproliferative potential of this plant against human tumor cells remain to be elucidated. In this study, we evaluated the antiproliferative effects of U. baccifera leaves extracts and fractions against a panel of human tumor cell lines in vitro besides a chemical evaluation of the most active sample by mass spectrometry (ESI-IT-MSn). The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antitumor agents; Medicinal plants; Chemical analysis. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100412 |
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| Silva,Suellen Maria Albuquerque da; Silva Neto,Geraldo José da; Nascimento,Ivenis Raphael Cavalcante do; Viana,Max Denisson Maurício; Lima,Alyne Almeida de; Bezerra,Pedro Henrique Simões; Bastos,Maria Lysete de Assis; Moreira,Magna Suzana Alexandre; Campesatto,Eliane Aparecida. |
| ABSTRACT In view of the traditional use of Tabebuia aurea for treating pain and inflammation, the antinociceptive pharmacological potential of T. aurea ethanolic extracts (TAEE) was investigated through in vivo experimental models. First, the MTT assay was conducted to determine the potential cytotoxicity of the TAEEs. Afterwards, the acetic acid-induced writhing test and the formalin-, and glutamate-induced nociception tests were performed on Swiss adult mice treated with TAEEs (100 and 200 mg/kg doses, p.o.), or saline solution (control groups, 10mL/kg, p.o.), or standard drugs: dipyrone 40 mg/kg (p.o.), and morphine 5,7 mg/kg (i.p). In the MTT assay, none of the tested concentrations demonstrated signals of cytotoxicity. In the in vivo experimental... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Analgesics; Nociception; Medicinal plants; Tabebuia aurea; Mice. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100443 |
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| Bayeux,M.C.; Fernandes,A.T.; Foglio,M.A.; Carvalho,J.E.. |
| The species Cordia curassavica (Boraginaceae), known popularly as "erva baleeira", is used in folk medicine for the treatment of several inflammatory processes and as a healing agent. The objective of the present study was to evaluate the antiedematogenic activity of crude dichloromethane extracts of Cordia curassavica and of the artemetin-enriched fraction. The crude extract and artemetin fraction were tested in the model of carrageenin-induced paw edema in male Swiss mice (25-30 g). The crude dichloromethane extract (300 and 1000 mg/kg, po, N = 6) showed significant antiedematogenic activity, reducing the edema by 42, 57 and 45% and 46, 62 and 69%, 3, 4 and 5 h after carrageenin administration, respectively. Indomethacin (10 mg/kg, po, N = 6) reduced the... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Cordia curassavica; Cordia verbenaceae; Antiedematogenic; Anti-inflammatory; Medicinal plants. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001000017 |
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| Lucarini,R.; Tozatti,M.G.; Silva,M.L.A.; Gimenez,V.M.M.; Pauletti,P.M.; Groppo,M.; Turatti,I.C.C.; Cunha,W.R.; Martins,C.H.G.. |
| This paper reports on the in vitro antibacterial and in vivo anti-inflammatory properties of a hydroethanolic extract of the aerial parts of Gochnatia pulchra (HEGP). It also describes the antibacterial activity of HEGP fractions and of the isolated compounds genkwanin, scutellarin, apigenin, and 3,5-O-dicaffeoylquinic acid, as evaluated by a broth microdilution method. While HEGP and its fractions did not provide promising results, the isolated compounds exhibited pronounced antibacterial activity. The most sensitive microorganism was Streptococcus pyogenes, with minimum inhibitory concentration (MIC) values of 100, 50 and 25 µg/mL for genkwanin and the flavonoids apigenin and scutellarin, respectively. Genkwanin produced an MIC value of 25 µg/mL against... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gochnatia pulchra; Anti-inflammatory activity; Antibacterial activity; Medicinal plants; Proinflammatory cytokines. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000900822 |
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| Lira,S.M.; Canabrava,N.V.; Benjamin,S.R.; Silva,J.Y.G.; Viana,D.A.; Lima,C.L.S.; Paredes,P.F.M.; Marques,M.M.M.; Pereira,E.O.; Queiroz,E.A.M.; Guedes,M.I.F.. |
| Diabetes mellitus is one of the most common chronic degenerative diseases, and it is estimated to increase worldwide to around 415 million and to impact 642 million in 2040. Research shows that some plants are sources of bioactive compounds against diabetes. Thus, the objective of this work was to evaluate the oral toxicity and the hypoglycemic effect of the aqueous extract of the leaves of Cnidoscolus quercifolius Pohl. Diabetes was induced in Swiss mice with streptozotocin and the mice were treated with an aqueous extract of C. quercifolius leaves for a period of 30 days. Phytochemical analysis showed that the extract was rich in flavonoids, catechins and triterpenoid, which did not show any mortality and behavioral alterations in mice treated with 200,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Faveleira; Diabetes mellitus; Medicinal plants; Hypoglycemic activity; Aqueous extracts. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001000612 |
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| Sartoratto,Adilson; Machado,Ana Lúcia M.; Delarmelina,Camila; Figueira,Glyn Mara; Duarte,Marta Cristina T.; Rehder,Vera Lúcia G.. |
| Essential oils from aerial parts of Mentha piperita, M. spicata, Thymus vulgaris, Origanum vulgare, O. applii, Aloysia triphylla, Ocimum gratissimum, O. basilicum were obtained by steam destillation using a Clevenger-type system. These oils were screened for antibacterial and anti-Candida albicans activity using bioautographic method. Subsequently, minimal inhibitory concentration from oils was determined by microdilution method. Most essential oil studied were effective against Enterococcus faecium and Salmonella cholerasuis. Aloysia triphylla and O. basilicum presented moderate inhibition against Staphylococcus aureus while only A. tryphila and M. piperita were able to control the yeast Candida albicans. The oils were analyzed by GC and GC-MS techniques... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Essential oil; Medicinal plants; Antimicrobial activity; Minimal inhibitory concentration. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822004000300001 |
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| Nascimento,Gislene G. F.; Locatelli,Juliana; Freitas,Paulo C.; Silva,Giuliana L.. |
| The antimicrobial activity of plant extracts and phytochemicals was evaluated with antibiotic susceptible and resistant microorganisms. In addition, the possible synergistic effects when associated with antibiotics were studied. Extracts from the following plants were utilized: Achillea millifolium (yarrow), Caryophyllus aromaticus (clove), Melissa offficinalis (lemon-balm), Ocimun basilucum (basil), Psidium guajava (guava), Punica granatum (pomegranate), Rosmarinus officinalis (rosemary), Salvia officinalis (sage), Syzygyum joabolanum (jambolan) and Thymus vulgaris (thyme). The phytochemicals benzoic acid, cinnamic acid, eugenol and farnesol were also utilized. The highest antimicrobial potentials were observed for the extracts of Caryophyllus aromaticus... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Plant extracts activity; Medicinal plants; Antimicrobial activity. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822000000400003 |
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| Johann,Susana; Pizzolatti,Moacir G.; Donnici,Cláudio L.; Resende,Maria Aparecida de. |
| Antifungal properties of extracts from eight Brazilian plants traditionally used in popular Brazilian medicine were tested against five clinically relevant Candida species, Cryptococcus neoformans, and Sporothrix schenckii. Results demonstrate that almost all extracts exhibited antifungal activity, at least against one of the microorganisms tested. The ethanolic extract from the leaves of Schinus terebinthifolius exhibited potential antifungal activity against C. glabrata and S. schenckii. Preliminary phytochemical analysis of extract from S. terebinthifolius showed the presence of biologically active compounds, namely saponins, flavonoids, triterpenes, steroids and tannins. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antifungal properties; Medicinal plants; Susceptibility test. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000400010 |
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| Anibal,Paula Cristina; Sardi,Janaina de Cássia Orlandi; Peixoto,Iza Teixeira Alves; Moraes,Julianna Joanna de Carvalho; Höfling,José Francisco. |
| Candida-associated denture stomatitis is the most common form of oral candidal infection, with Candida albicans being the principal etiological agent. Candida adheres directly or via an intermediary layer of plaque-forming bacteria to denture acrylic. Despite antifungal therapy to treat denture stomatitis, infection is reestablished soon after the treatment ceases. In addition, many predisposing factors have been identified as important in the development of oral candidiasis, including malnourishment, common endocrine disorders, such as diabetis mellitus, antibacterial drug therapy, corticosteroids, radiotherapy and other immunocompromised conditions, such as acquired immunodeficiency syndrome (AIDS). These often results in increased tolerance to the most... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida spp.; Antifungals; Medicinal plants; Extracts; Essential oil. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000400001 |
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| Prado,Guilherme; Altoé,Aline F.; Gomes,Tatiana C. B.; Leal,Alexandre S.; Morais,Vanessa A. D.; Oliveira,Marize S.; Ferreira,Marli B.; Gomes,Mateus B.; Paschoal,Fabiano N.; Souza,Rafael von S.; Silva,Daniela A.; Madeira,Jovita E. G. Cruz. |
| The media claims for the consumption of natural resource-based food have gradually increased in both developing and developed countries. The interest in the safety of these products is partially due to the possible presence of toxigenic fungi acting as mycotoxin producers, such as aflatoxins produced during the secondary metabolism of Aspergillus flavus, A. parasiticus and A. nomius. Aflatoxins, mainly aflatoxin B1, are directly associated with liver cancer in human beings. This paper is aimed at evaluating the presence of aflatoxin B1 in a few vegetable drugs, dried plant extracts and industrialized products traded in 2010 in the city of Belo Horizonte, State of Minas Gerais, Brazil. The method used for the quantification of aflatoxin B1 was based on... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Medicinal plants; Fungi; Mycotoxin; High-performance liquid chromatography; HPLC. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000400026 |
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| Registros recuperados: 134 | |
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