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Registros recuperados: 142
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Bark Extract of Bathysa cuspidata in the Treatment of Liver Injury Induced by Carbon Tetrachloride in Rats BABT
Gonçalves,Reggiani Vilela; Matta,Sérgio Luis Pinto da; Novaes,Rômulo Dias; Leite,João Paulo Viana; Peluzio,Maria do Carmo Gouveia; Vilela,Emerson Ferreira.
The aim of this study was to investigate the effect of bark extract Bathysa cuspidata (BCE) in the reconstitution of hepatic parenchyma and stroma after dysfunction induced by the CCl4. Liver lesions were induced by intraperitoneal administration of CCl4 (1 mL/kg) every 48 h for 12 days. The animals were treated with B. cuspidata extract (BCE) administered by gavage for another 12 days. Forty-nine rats were randomized into seven treatment groups with seven animals receiving CCl4, BCE (200, or 400 mg/kg) and the vehicle DMSO alone, or in different combinations. The extract alone showed no evidence of hepatic toxicity. In general, rats acutely exposed to CCl4 without the treatment with BCE presented high ALT and AST serum levels and high tissue content of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant defense; Biotechnology; Hepatotoxicity; Phytotherapy; Pathology.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000400504
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Retrospective review and systematic study of mammary tumors in dogs and characteristics of the extracellular matrix Braz. J. Vet. Res. Anim. Sci.
Martins,Ana Maria Cristina Rabello Pinto da Fonseca; Tamaso,Elia; Guerra,José Luiz.
The aim of the present study was to perform a retrospective review, from 1932 to 1999, in order to establish the number of cases of mammary tumors in dogs in the records at the Pathology Department of Faculdade de Medicina Veterinária - USP, as well as the presence of desmoplasia and cartilaginous and bone metaplasia in 578 of these tumors. Among the 537 malignant tumors, 13.05% were simple tubular adenocarcinomas, 3.91% were complex tubular adenocarcinomas, 7.26% simple papillary adenocarcinomas, 4.28% complex papillary adenocarcinomas , 23.27% simple papillary cystadenocarcinomas ,8.37% complex papillary cystadenocarcinomas,16.38% simple solid adenocarcinomas ,6.70% complex solid adenocarcinomas, 2.04% simple spindle cell carcinomas, 1.11% simple spindle...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mammary neoplasms; Dogs; Pathology; Extracellular matrix; Frequency.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962002000100007
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Association between prostate cancer and schistosomiasis in young patients: a case report and literature review BJID
Bacelar,Albert; Castro,Larissa G.M.C.; Queiroz,Aristides Cheto de; Café,Eduardo.
This case report refers to a 47-year old patient with prostate cancer associated with schistosomiasis mansoni, who was submitted to radical prostatectomy. This is the third report published in the literature with respect to this association, and up to the present time it is still not known whether a cause and effect relationship exists between the two pathologies. The association between schistosomiasis and cancer has been well-documented in bladder cancer; however, there are no data yet proving the association of this disease with prostatic neoplasia. In this report, a third documented case of prostatic adenocarcinoma and schistosomiasis mansoni is described and a literature review is performed.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Prostate cancer; Schistosomiasis; Prostatectomy; Pathology.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500014
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An experimental model of hemolysis-induced acute pancreatitis BJMBR
Saruc,M.; Yuceyar,H.; Turkel,N.; Ozutemiz,O.; Tuzcuoglu,I.; Yuce,G.; Huseyinov,A..
The literature indicates that acute pancreatitis is a complication of massive hemolysis with a prevalence of about 20%. We describe an experimental model of hemolysis-induced acute pancreatitis. Hemolytic anemia was induced in rats by a single ip injection of 60 mg/kg of 20 mg/ml acetylphenylhydrazine (APH) in 20% (v/v) ethanol on the first experimental day (day 0). One hundred and fifty Wistar albino rats weighing 180-200 g were divided into three groups of 50 animals each: groups 1, 2 and 3 were injected ip with APH, 20% ethanol, and physiological saline, respectively. Ten rats from each group were sacrificed on study days 1, 2, 3, 4 and 5. Serum amylase, lipase levels and pancreatic tissue tumor necrosis factor-alpha (TNF-alpha) and platelet-activating...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hemolysis; Pancreatitis model; Experimental pancreatitis; Etiology; Pathology.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000700008
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The role of complement in the early phase of Leishmania (Leishmania) amazonensis infection in BALB/c mice BJMBR
Laurenti,M.D.; Örn,A.; Sinhorini,I.L.; Corbett,C.E.P..
Complement-depleted and -non-depleted BALB/c mice were inoculated with Leishmania (Leishmania) amazonensis promastigotes into the hind footpad to study the role of the complement system in cutaneous leishmaniasis. Total serum complement activity was measured by hemolytic assay and C3 fragment deposit at the inoculation site was determined by direct immunofluorescence in the early period of infection, i.e., at 3, 24, 48 h and 7 days post-infection. The inflammatory reaction and the parasite burden were evaluated in the skin lesion at 7 and 30 days post-infection. Total serum complement activity decreased in the early phase of infection, from 3 to 24 h, in non-depleted mice compared to non-infected and non-depleted mice. C3 fragment deposit at the site of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cutaneous leishmaniasis; Leishmania (Leishmania) amazonensis; Complement; Pathology.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300021
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Cytokine profile and pathology in human leishmaniasis BJMBR
Ribeiro-de-Jesus,A.; Almeida,R.P.; Lessa,H.; Bacellar,O.; Carvalho,E.M..
The clinical spectrum of leishmaniasis and control of the infection are influenced by the parasite-host relationship. The role of cellular immune responses of the Th1 type in the protection against disease in experimental and human leishmaniasis is well established. In humans, production of IFN-<FONT FACE="Symbol">g</font> is associated with the control of infection in children infected by Leishmania chagasi. In visceral leishmaniasis, an impairment in IFN-<FONT FACE="Symbol">g</font> production and high IL-4 and IL-10 levels (Th2 cytokines) are observed in antigen-stimulated peripheral blood mononuclear cells (PBMC). Moreover, IL-12 restores IFN-<FONT FACE="Symbol">g</font> production and enhances the cytotoxic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Leishmaniasis; Human leishmaniasis; Cytokines; Pathology; Immunological responses.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000100020
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Pitfalls in the assessment of murine atherosclerosis BJMBR
Catanozi,S.; Rocha,J.C.; Passarelli,M.; Chiquito,F.C.; Quintão,E.C.R.; Nakandakare,E.R..
This review provides examples of the fact that different procedures for the measurement of atherosclerosis in mice may lead to interpretation of the extent of atherosclerosis having markedly different biological and clinical significance for humans: 1) aortic cholesterol measurement is highly sensitive for the detection of early and advanced atherosclerosis lesions, but misses the identification of the location and complexity of these lesions that are so critical for humans; 2) the histological analysis of the aortic root lesions in simvastatin-treated and control mice reveals similar lesion morphology in spite of the remarkable simvastatin-induced reduction of the aortic cholesteryl ester content; 3) in histological analyses, chemical fixation and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Atherosclerosis; Animal models; Disease models; Aorta; Pathology.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600001
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Detection of Mycobacterium avium in pet birds BJM
Godoy,Silvia Neri; Sakamoto,Sidnei Miyoshi; Paula,Cátia Dejuste de; Catão-Dias,José Luiz; Matushima,Eliana Reiko.
The present study is a report on the presence of Mycobacterium avium in four birds of the psittaciform order kept as pets. Anatomopathological diagnosis showed lesions suggestive of the agent and presence of alcohol-acid resistant bacilli (AARB) shown by the Ziehl-Neelsen staining. The identification of Mycobacterium avium was performed by means of PRA (PCR Restriction Analysis). DNA was directly extracted from tissue of the lesions and blocked in paraffin. The role of this agent in pet bird infection is discussed, as well as its zoonotic potential.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mycobacterium avium; Psittacines; Pathology; Birds.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000200011
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Canine hypertrophic osteopathy associated with extra-thoracic lesions Ciência Rural
Headley,Selwyn Arlington; Ribeiro,Eduardo Alcântara; Santos,Gustavo José Von G. dos; Bettini,Carlos Maia; Mattos Júnior,Ewaldo.
Canine hypertrophic osteopathy is described in a dog that presented extra-thoracic lesions, mainly in the liver. Hepatic lesions were characterized by necrosis, hemorrhage, severe hydropic degeneration of centrolobular hepatocytes, proliferation of epithelial cells of bile ducts, and mild biliary stasis. The disease syndrome was diagnosed based on clinical signs, radiological evaluation, and inspection of macerated bones.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypertrophic osteopathy; Dog; Pathology; Radiology; Liver.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782005000400033
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Renal cell carcinoma with peritoneal carcinomatosis in a mare Ciência Rural
Mesquita,Leonardo Pereira; Mesquita Neto,Francisco Duque de; Varaschin,Mary Suzan; Wouters,Angélica Terezinha Barth; Wouters,Flademir.
ABSTRACT: Renal cell carcinoma, especially with extensive involvement of peritoneal cavity, is rarely described in horses. This study described a case of renal cell carcinoma in an 8-year-old mare, which presented with an enlargement in the left flank, decreased appetite and straining to defecate. Clinically, a tumor in the left retroperitoneal space was detected by rectal examination and ultrasonography. The animal died after one month of clinical evolution. At necropsy, the left kidney was completely effaced by a 50cm in diameter, irregular, round, lobulated cystic mass with necro-hemorrhagic areas. Within the peritoneal cavity, there was severe hemoperitoneum and numerous sessile and pedunculated masses ranging from 2.0 to 15.0cm diameter that were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Equine; Renal neoplasia; Pathology; Kidney; Tumor.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000100602
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Acute renal failure in a horse following bee sting toxicity Ciência Rural
Ribeiro,Paula Reis; Bianchi,Matheus Viezzer; Henker,Luan Cleber; Gonzales,Fernando; Pavarini,Saulo Petinatti.
ABSTRACT: Bee envenomation is frequent in humans and dogs, but uncommon in horses. This study aimed to describe a case of acute renal failure following mass envenomation in a horse. A mare was attacked by a swarm of bees and showed reluctance to move, epistaxis, and dark-brown urine. Biochemical exams revealed increase in urea and creatine serum levels. The mare did not respond to treatment and euthanasia was elected after four days of clinical course. At the necropsy, there were multifocal pinpoint to elevated skin lesions associated with edema and hemorrhage, which extended to the subcutaneous tissue and skeletal muscle, and the kidneys were diffusely dark-brown and friable. Microscopically, renal tubules were distended and filled with an orange-red,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute renal failure envenomation; Pathology; Veterinary toxicology.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000500551
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Vertebral hemangiosarcoma as a cause of spinal cord compression in a horse Ciência Rural
Barros,Claudio Severo Lombardo de.
A case compression of the spinal cord in a horse by a tumor located in the vertebra is described. A 10-year-old gelding was euthanized after being found recumbent with hind limb paresis of unknown duration. At necropsy an hemangiosarcoma was detected in the vertebral body of T3. The tumoral mass invaded upwards through the bone tissue of the vertebral body into the vertebral canal, compressing the spinal cord and causing Wallerian degeneration at T1-3 levels of the cord.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bone tumors; Equine; Pathology.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84781997000300024
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Clinical, parasitological and obstetric observations in pregnant bitches with experimental toxoplasmosis Ciência Rural
Bresciani,Katia Denise Saraiva; Toniollo,Gilson Hélio; Costa,Alvimar José da; Sabatini,Gustavo Adolfo; Moraes,Flávio Ruas de.
Eight pregnant mixed breed bitches, serologically negative for Toxoplasma gondii, were divided into three groups. Group I : bitches 01 and 02 (1.0 x 10(7) tachyzoites of Toxoplasma gondii, subcutaneous route); Group II: bitches 03, 04 and 05 (1.5 x 10(4) oocysts, oral route); Group III: bitches 06, 07 and 08 (as control). Clinical and obstetric examinations were conducted twice a day on each bitch, and weekly ultra-sonografic evaluations were performed until the end of pregnancy. From the 2nd day the bitches presented clinical alterations such as fever, nasal flowing, lachrymation, prostration, lymphadenopathy, premature parturition, abortion and fetal death. In Group I, Toxoplasma gondii was isolated from the bitches urine (day 10) and saliva (day 18)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Toxoplasmosis; Toxoplasma gondii; Pregnant bitches; Pathology.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782001000600020
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Pneumonia by Cryptococcus neoformans in a goat in the Southern region of Brazil Ciência Rural
Bianchi,Ronaldo Michel; Cecco,Bianca Santana de; Schwertz,Claiton Ismael; Panziera,Welden; Andrade,Caroline Pinto de; Spanamberg,Andreia; Ravazzolo,Ana Paula; Ferreiro,Laerte; Driemeier,David.
ABSTRACT: This report describes the clinical, pathological, and molecular aspects of a pneumonia by Cryptococcus neoformans in a goat in the Southern region of Brazil. A goat with a history of prolonged transportation presented dyspnea, nasal discharge and cough, and was subjected to necropsy, histopathology, and mycological evaluation. Grossly, cranio-ventral pulmonary consolidation was observed, characterized by firm and grayish areas interspersed with dark red foci. Histopathology of the lungs showed areas of parenchymal necrosis, containing blastoconidia with a slightly basophilic central cell, surrounded by an unstained capsule. It was associated with moderate granulomatous inflammatory infiltrate and peripheral fibrosis. The capsule and fungus cell...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Goats; Respiratory diseases; Pathology; Mycology; Molecular diagnosis.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001000551
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Fatal systemic Mortierella wolfii infection in a neonatal calf in southern Brazil Ciência Rural
Bianchi,Ronaldo Michel; Vielmo,Andréia; Schwertz,Claiton Ismael; Cabreira,Adan; Rocha,Jéssica Goulart da; Siqueira,Franciele Maboni; Pavarini,Saulo Petinatti.
ABSTRACT: This study described the pathological and microbiological aspects of a fatal systemic Mortierella wolfii infection in a neonatal calf in southern Brazil. The calf was born clinically normal, but on the third day of life it presented apathy, unilateral hypopyon, and neurological signs, and in the next day it was euthanized. At necropsy, multiple soft, and white-yellow nodules were observed in the liver, spleen, kidneys, mesenteric lymph nodes, heart, and lungs. In the brain, reddish, and friable areas were found. In the eye, there were anterior and posterior synechiae, diffuse thickening of choroid, and anterior chamber filled by whitish and friable material. Microscopically, areas of necrosis, pyogranulomatous inflammation, vasculitis,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cattle diseases; Fungal diseases; Pathology; Molecular diagnosis.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000100551
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Mannheimia haemolytica pleuropneumonia in goats associated with shipping stress Ciência Rural
Taunde,Paula Augusto; Argenta,Fernando Froner; Bianchi,Ronaldo Michel; Cecco,Bianca Santana de; Vielmo,Andréia; Lopes,Bruna Corrêa; Siqueira,Franciele Maboni; Andrade,Caroline Pinto de; Snel,Gustavo Geraldo Medina; Barros,Claudio Severo Lombardo de; Sonne,Luciana; Pavarini,Saulo Petinatti; Driemeier,David.
ABSTRACT: This study described the epidemiological, clinical, pathological and bacteriological aspects of Mannheimia haemolytica pleuropneumonia in goats associated with shipping stress. Forty goats transported from the Northeast to the Southern region of Brazil died during shipment, or 2-3 days after unloading. Clinical signs included dyspnea, mucopurulent nasal discharge, and coughing. All goats were necropsied, and multiple tissues were collected for histopathological analysis and involved agent identifications. All lungs showed pulmonary consolidation, predominantly affecting the cranioventral lobes, in addition to the marked fibrinous pleuritis, pleural thickening, and pleural adhesions, that affected 90% of the goats. Histologically, there was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Goat diseases; Respiratory diseases; Pathology; PCR.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000100451
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Fatal asphyxia due to laryngeal displacement by large-sized prey in a Guiana dolphin (Sotalia guianensis), Brazil Ciência Rural
Mariani,Daniela Bueno; Guimarães,Juliana Plácido; Batista,Renata Guedes; Brum,Andrei; Groch,Kátia Regina; Díaz-Delgado,Josué; Parente,Jociery Einhardt Vergara.
ABSTRACT: The Guiana dolphin (Sotalia guianensis) is a small odontocete distributed from Santa Catarina state, Brazil, to Honduras. Although it is currently considered “near threatened” by the International Union for Conservation of Nature, considerable knowledge on health and disease aspects of this species has been gained over the last decade. The main threats for the species are represented by multiple anthropic factors. Guiana dolphins feed on a variety of taxa, primarily teleosts, crustaceans, and cephalopods. Herein, we reported a case of severe laryngeal displacement and esophageal impaction with ulceration associated with a deglutted adult leatherjacket (Oligoplites sp.). This fish species is not a common prey item of Guiana dolphins’ diet. Severe...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Deglutition; Larynx; Cetacean; Pathology; Predator-prey interaction; Impaction; Esophageal ulcer.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000200550
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Chronic cardiomyopathy and encephalic spongy changes in sheep experimentally fed Ateleia glazioviana Ciência Rural
Raffi,Margarida Buss; Rech,Raquel Rubia; Sallis,Elisa Simone Viegas; Rodrigues,Aline; Barros,Claudio Severo Lombardo de.
Fifteen mature crossbred sheep were fed different daily amounts (2.5-35g kg-1 bw) of the fresh green leaves of Ateleia glazioviana for different periods of time (1-24 days). One sheep was not fed the plant and served as a control. All 16 sheep were euthanatized at different stages of the experiment, necropsied, and several organs, including heart and brain were evaluated histologically. Samples of five brain regions from three affected sheep were evaluated by electron microscopy. Clinical signs observed in three sheep included depression, anorexia, general weakness, staggering gait and prolonged recumbency. One sheep had signs of congestive heart failure. Necropsy findings included subcutaneous dependent edema and edema of the body cavities in two sheep...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Poisonous plants; Ateleia glazioviana; Cardiomyopathy; Cerebral spongy degeneration; Pathology; Sheep diseases.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782006000600030
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Natural Sarcocystis gigantea infection in sheep from Southern Brazil Ciência Rural
Damboriarena,Pedro Araujo; Silveira,Caroline Silva; Morais,Raissa Moreira; Anjos,Bruno Leite.
ABSTRACT: Protozoal diseases caused by species of Sarcocystiscan cause serious damage in sheep flocks, inducing decreased growth conversion rates and partial or complete loss of carcasses at the slaughterhouse. This article describes an outbreak of Sarcocystis giganteainfection in sheep slaughtered in a farm in Rio Grande do Sul State, Brazil. Between July and September 2013, three sheep showed multiple nodules in the esophagus that were microscopically characterized as encapsulated cysts filled with elongated, basophilic, nucleated structures morphologically consistent with S. giganteabradyzoites. Diagnosis was made based on the epidemiological, macroscopic, and microscopic findings. This is the first report of this infection in sheep in Rio Grande do...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sarcocystosis in sheep; Apicomplexa; Pathology.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000701229
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Anatomo-pathological aspects of parasitism by nematodes of the superfamily Metastrongyloidea in wild crab-eating fox (Cerdocyon thous) in Midwestern Brazil Ciência Rural
Ferreira Júnior,Jair Alves; Blume,Guilherme Reis; Sousa,Susy Karoline Hermes de; Carvalho,Clarissa Machado de; Gardiner,Chris.
ABSTRACT: Nematodes of the superfamily Metastrongyloidea affect the respiratory, cardiovascular, and nervous systems of domestic carnivores and are uncommonly detected in wild animals. This report describes the lesions associated with pulmonary parasitism by nematodes of the superfamily Metastrongyloidea in a wild crab-eating fox ( Cerdocyon thous ) in the Federal District, Brazil. Grossly, there was pulmonary hyperemia, edema, and emphysema. Microscopically, there was granulomatous arteritis associated with intravascular metastrongylid. The anatomical location, characteristic lesion, and histological features of the parasite suggested that the nematode involved in this case is Angiostrongylus vasorum . This worm is frequently reported parasitizing...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiostrongylus; Nematode; Wild canids; Pathology.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000200501
Registros recuperados: 142
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