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	Provedor de dados ArchiMer (24) Autor Marcaillou-le Baut, Claire (24) Lassus, Patrick (5) Mondeguer, Florence (5) Amzil, Zouher (4) Belin, Catherine (4) Truquet, Philippe (4) Bohec, Madeleine (3) Le Dean, Loic (3) Antoine, Elisabeth (2) Bardouil, Michele (2) Bornet, Benjamin (2) Dupuy, Beatrice (2) Haure, Joel (2) Hess, Philipp (2) Masselin, Pierre (2) Penisson, Christian (2) Abadie, Eric (1) Abarnou, Alain (1) Bardin, B. (1) Baron, Bruno (1) Mais... Palavra-chave Dinophysis acuminata (4) Alexandrium (3) France (3) Monitoring (3) Okadaic acid (3) ANE (2) Biological poisons (2) ISSR (2) Phytoplankton (2) Pseudo nitzschia (2) Red tides (2) Surveillance (2) Toxicity (2) Toxicité (2) AZA (1) Acide okadaïque (1) Acyl esters (1) Algae (1) Algal blooms (1) Aquaculture crevette (1) Mais... Tipo do documento Text (24) Ano 2012 (1) 2011 (1) 2010 (1) 2009 (1) 2008 (2) 2006 (1) 2005 (3) 2004 (1) 2001 (1) 1999 (1) 1996 (2) 1995 (1) 1992 (1) 1990 (3) 1988 (1) 1987 (1) 1983 (2) Mais... País France (24) Idioma Francês (15) Inglês (9)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 24 Primeira ... 1 2 ... Última Field and mesocosm trials on passive sampling for the study of adsorption and desorption behaviour of lipophilic toxins with a focus on OA and DTX1 ArchiMer Fux, E; Marcaillou-le Baut, Claire; Mondeguer, Florence; Bire, R; Hess, Philipp. It has been demonstrated that polymeric resins can be used as receiving phase in passive samplers designed for the detection of lipophilic marine toxins at sea and was referred to as solid phase adsorption toxin tracking (SPATT). The present study describes the uptake and desorption behaviour of the lipophilic marine toxins okadaic acid (OA) and dinophysistoxin-1 (DTX1) from Prorocentrum lima cultures by five styrene-divinylbenzene based polymeric resins Sepabeads (R) SP850, Sepabeads (R) SP825L, Amberlite (R) XAD4, Dowex (R) Optipore (R) L-493 and Diaion (R) HP-20. All resins accumulated OA and DTX1 from the P. lima culture with differences in adsorption rate and equilibrium rate. Following statistical evaluation, HP-20, SP850 and SP825L demonstrated... Tipo: Text Palavras-chave: Polymeric resin; Dinophysistoxin 1; Okadaic acid; SPATT; Prorocentrum lima. Ano: 2008 URL: http://archimer.ifremer.fr/doc/2008/publication-4739.pdf Etude d'un système de filtration de l'eau de mer pour l'alimentation des bassins conchylicoles insubmersibles durant des efflorescences toxiques. Rapport de fin de contrat : Cas d'une efflorescence à Alexandrium minutum et à Dinophysis spp ArchiMer Mondeguer, Florence; Marcaillou-le Baut, Claire. Le littoral français est touché tous les ans par des proliférations d'algues toxiques dont l'ampleur géographique et la durée sont très variables selon les genres/espèces et les années. Par exemple, à partir du mois de mai, voire fin avril certaines années, les côtes sud de la Bretagne et celles des Pays de la Loire sont touchées par des proliférations de Dinophysis spp, genre responsable des intoxications diarrhéiques et cause la plus fréquente des fermetures de zones conchylicoles. Depuis 1988, la côte nord de la Bretagne est exposée à des efflorescences à Alexandrium minutum, producteur de toxines paralysantes. Ces fermetures répétées s'accompagnent d'une diminution, voire d'une cessation d'activité pour les établissements d'expédition car... Tipo: Text Ano: 2005 URL: http://archimer.ifremer.fr/doc/00154/26512/24630.pdf Etude de la décontamination de moules toxiques (toxines diarrhéiques) en laboratoire et en milieu naturel ArchiMer Marcaillou-le Baut, Claire; Bardin, B.; Bardouil, Michele; Bohec, Madeleine; Le Dean, Loic; Masselin, Pierre; Truquet, Philippe. Two studies of depuration, one in laboratory conditions and the other one in an oyster's pond were performed using 2 sets of contaminated mussels with diarrhetic toxins at a high and a low level (3 and 1 M.U.). Depuration kinetics were followed both by the adult mouse test and okadaïc acid analysis. Results are - in the pond, high toxic mussels need about 20 days to become eatable (toxicity level : 0.5 M.U.g-1 digestive glands), -this time decreases when the initial toxicity is low but it increases when mussels are underfed, - a good correlation is observed between the total toxicity and okadaïc acid concentration. Tipo: Text Ano: 1990 URL: http://archimer.ifremer.fr/doc/00075/18595/16148.pdf Toxicité inexpliquée des moules de la baie de Lazaret (Toulon) entre novembre 1993 et mai 1994 ArchiMer Amzil, Zouher; Marcaillou-le Baut, Claire; Bohec, Madeleine. Depuis janvier 1993, des épisodes de forte toxicité des coquillages ont été observés lors des contrôles de routine en différents points des côtes françaises. Les souris ayant reçu des extraits de coquillages, par voie intrapéritonéale, présentaient des symptômes de type neurologique et mouraient au bout de 5 à 15 minutes. Cette toxicité n'a pu être attribuée à l'existence de phycotoxines connues. Les études préliminaires réalisées sur les glandes digestives de moules toxiques, récoltées lors d'un de ces épisodes (rade de Toulon), nous ont permis d'acquérir les données suivantes : le principe actif possède une forte polarité, il est thermostable, et il est stable dans le temps et en milieu acide. L'intoxication par voie orale chez la souris a permis de... Tipo: Text Ano: 1996 URL: http://archimer.ifremer.fr/doc/00075/18596/16149.pdf Contribution to toxicity assessment of Dinophysis acuminata (Dinophyceae) ArchiMer Marcaillou-le Baut, Claire; Mondeguer, Florence; Gentien, Patrick. Blooms of Dinophysis in French coastal waters are implicated in most bans on marketing commercial bivalves. However, the relation between Dinophysis cell density and shellfish toxicity is not always consistent. Discrepancies may be due to the simple fact that it is nearly impossible to compare an integral over a few days (shellfish toxin content) and water samples. Furthermore, it seems that cells may have a variable specific toxicity. This work focuses on the variability in cell toxicity taking into account recent findings and using liquid chromatography coupled to mass spectrometry with an ion trap and electrospray interface. Esterified analogues of okadaic acid (DTX-4 and diol-esters) have been identified in cultures of Prorocentrum lima, another... Tipo: Text Palavras-chave: Liquid chromatography electrospray ionization mass spectrometry; Okadaic acid; Dinophysistoxins; Dinophysis acuminata. Ano: 2005 URL: http://archimer.ifremer.fr/doc/2005/publication-605.pdf Contamination de l'etang de Thau par Alexandrium tamarense. Episode de novembre a decembre 1998 ArchiMer Abadie, Eric; Zouher, Amzil; Belin, Catherine; Comps, Marie-annick; Elziere-papayanni, Panayota; Lassus, Patrick; Le Bec, Claude; Marcaillou-le Baut, Claire; Nezan, Elizabeth; Poggi, Robert. A bloom of the toxic dinoflagellate Alexandrium tamarense was observed for the first time in Thau iagoon between November and December 1998. Maximum cell concentrations detected in shellfish farming areas (85 000 Cells/1) were high enough to make mussels and clams unsuitable for human consumption (max. 850 ug. STX eq.100 g'1) while toxic levels in oysters did not exceed, or even reach, the international public health threshold established for PSP toxins. This event, new to French Mediterranean waters, was investigated by both local and national veterinary services and by the Ifremer teams involved in the National Monitoring Network for Phytoplankton and Phycotoxines (Réphy). The chronological and operational description of the event was compared with data... Tipo: Text Palavras-chave: Alexandrium; Monitoring; Toxic dinoflagellates; Thau lagoon; Alexandrium; Surveillance; Dinoflagellés toxiques; Etang de Thau. Ano: 1999 URL: http://archimer.ifremer.fr/doc/1999/rapport-884.pdf Development of sequence characterized amplified region markers from intersimple sequence repeat fingerprints for the molecular detection of toxic phytoplankton Alexandrium catenella (Dinophyceae) and pseudo-Nitzschia pseudodelicatissima (Bacillariophyceae) from French coastal waters ArchiMer Bornet, Benjamin; Antoine, Elisabeth; Francoise, Sylvaine; Marcaillou-le Baut, Claire. Harmful algal blooms are a serious threat to shellfish farming and human health all over the world. The monitoring of harmful algae in coastal waters originally involved morphological identification through microscopic examinations, which was often difficult unless performed by specialists and even then often did not permit identification of toxic species. More recently, specific molecular markers have been used to identify specific phytoplankton species or strains. Here we report on the use of the intersimple sequence repeat (ISSR) technique to develop specific sequence characterized amplified region markers (SCAR) and to identify with these tools two toxic species in French coastal waters, the diatom Pseudo-nitzschia pseudodelicatissima (Hasle) Hasle and... Tipo: Text Palavras-chave: SCAR; Pseudo nitzschia; Monitoring; Molecular identification; ISSR; Alexandrium. Ano: 2005 URL: http://archimer.ifremer.fr/doc/2005/publication-780.pdf REPHY (Réseau de Surveillance du Phytoplancton et des Phycotoxines). Méthodes de détection des phycotoxines diarrhéïques (DSP) et paralysantes (PSP). Méthodes biologiques sur souris ArchiMer Belin, Catherine; Marcaillou-le Baut, Claire; Amzil, Zouher; Ledoux, Martial. This document describes and harmonizes detection methods of diarrheic (DSP) and paralytic (PSP) phycotoxins, for the laboratories of the Direction of Coastal Environment of IFREMER, which work in the framework of the French Phytoplankton and Phycotoxins Monitoring Network. These toxins, produced by a few phytoplankton species which regularly occur in sea water, accumulate in shellfish, which become toxic. Analysis is performed on an extract of digestive gland (DSP), or of total flesh (PSP), of shellfish. The described methods are meuse-tests, which are, at the present time, the only methods available to be used in the framework of a monitoring network. The method for diarrheic toxins is not standardized, with a threshold adapted for monitoring purposes. At... Tipo: Text Palavras-chave: Phycotoxines; Méthode de détection des toxines; Test-souris; Toxines diarrhéïques; DSP; Toxines paralysantes; PSP; Surveillance; Phycotoxins; Toxin detection method; Mouse-test; Diarrheic toxins; DSP; Paralytic toxins; PSP; Monitoring. Ano: 1996 URL: http://archimer.ifremer.fr/doc/00429/54106/55438.pdf Mise au point d'un test microcrustacé marin ArchiMer Marcaillou-le Baut, Claire; Le Dean, Loic; Chiffoleau, Jean-francois; Sanjuan, Jane. Because of the low number of currently available toxicity tests for marine environment, the authors describe an experimental procedure using a marine copepod : Tigriopus brevicornis. This method can be used to quantify the 50 % inhibition of larval production or growth. The variability in controls larval production reaches about 9 %. The toxicity of two contaminants : tributyltin (TBTF) and cadmium chloride (CdCl2) was determined with this method and the 50 % decreases in larval production are respectively 1,4 µg/l (TBTF) and 61 µg/l (Cd++). Tipo: Text Palavras-chave: Test; Toxicité; Copépode; Étain; Cadmium; Test; Toxicity; Copepod; Tin; Cadmium. Ano: 1988 URL: http://archimer.ifremer.fr/doc/00139/25036/23145.pdf Détection de l'acide okadaïque dans les moules toxiques : comparaisons de bioéssais ArchiMer Marcaillou-le Baut, Claire; Masselin, Pierre; Bohec, Madeleine; Truquet, Philippe; Amzil, Zouher; Pouchus, Francois; Le Boterff, Jean; Verbist, Jean-françois; Vernoux, Jean-paul; Marais, Chantal; Simon, Jean-françois; Nizard, Gabrielle; Mercier, Géraldine; Choumiloff, Roxelan; Baron, Bruno. Cette étude est le résultat d'un travail de trois équipes: elle porte sur la comparaison du test souris avec différents bioessais déjà pratiqués en routine dans les laboratoires participants. Ces bioessais sont : - un test sur micro crustacé dont la méthodologie est normalisée et qui est très utilisé en écotoxicologie aquatique ; - un test de cytotoxicité à court terme qui a été mis au point pour cette étude. Tipo: Text Ano: 1992 URL: http://archimer.ifremer.fr/doc/00139/25035/23144.pdf The toxins of marine microalgae ArchiMer Marcaillou-le Baut, Claire. Exotoxins exert direct deleterious effects on flora and fauna: Some of them damage the cellular membrane, others have inhibiting effects on phytoplanktonic populations susceptible to coming into competition. In terms of pollution, exotoxins are especially a significant menace for aquaculture and although some are also bothersome for Man, we will not treat them here. Endotoxins accumulate in the food chain and reach humans via consumed sea products. They constitute a potential risk for human health and a scourge for the shellfish farming economy. Tipo: Text Palavras-chave: Molecular structure; Toxicogenesis; Phycotoxyn; Toxin; Marine micro algae. Ano: 2006 URL: http://archimer.ifremer.fr/doc/2006/publication-2323.pdf Dinophysis acuminate (dinophyceae), une espèce à géométrie variable sur les côtes françaises ArchiMer Lassus, Patrick; Marcaillou-le Baut, Claire. Tipo: Text Palavras-chave: Morphologie; Variabilité; Ultrastructure; Croissance; France; Dinophysis acuminata; Europe; Milieu marin; Zone côtière; Phytoplancton; Pyrrophycophyta; Algae; Thallophyta; Morphology; Variability; Ultrastructure; Growth; France; Europe; Marine environment; Coastal zone; Phytoplankton; Pyrrophycophyta; Algae; Thallophyta. Ano: 1995 URL: http://archimer.ifremer.fr/doc/00133/24468/22484.pdf Dinoflagelles toxiques sur les cotes francaises durant l'ete 1983. Synthese des connaissances sur les efflorescences estivales de Dinophysis et Gyrodinium. ArchiMer Marcaillou-le Baut, Claire. The authors summarize briefly the information given by the foreign studies on two toxic marine dinoflagellates and present the situations observed in 1983 on the coasts of Normandy and Brittany. Tipo: Text Palavras-chave: France; ANE; Gyrodinium aureolum; Dinophysis acuminata; Phytoplankton; Red tides; Biological poisons; Algal blooms. Ano: 1983 URL: http://archimer.ifremer.fr/doc/1983/publication-1804.pdf Etude de la dégradation et de la toxicité de la roténone en milieu marin ArchiMer Marcaillou-le Baut, Claire. The use of rotenone as a means of predators eradication is necessary for the success of shrimps culture. Because these compound is a fish toxicant, some precautions have to be tacken in order to avoid the contamination of marine environment by the residual waters ; so the dissipation and the toxicity have been studied together in laboratory and in field assays. It appears that a delay of 15 days should be respected : this time is required for a total disappearing of the residual toxicity. Tipo: Text Palavras-chave: Aquaculture crevette; Roténone; Toxicité; Dégradation; Shrimps culture; Rotenone; Toxicity; Degradation. Ano: 1987 URL: http://archimer.ifremer.fr/doc/00138/24949/23042.pdf Les polychlorobiphényles (PCB) en milieu marin : biogéochimie et écotoxicologie ArchiMer Marchand, Michel; Abarnou, Alain; Marcaillou-le Baut, Claire. This report synthesizes the knowledge on the behaviour, bioconcentration processes and ecotoxicity ofPCB in the marine environment. Contamination levels of the French coasts are examined. Concentration levels, mechanisms andfluxes between geochemicai reservoirs are assessed. Emphasis is given on subiethai effects and toxicity mechanisms. Quality standards used in European Community countries are listed. Conclusions and recommendations for environmentai management and research are given. Tipo: Text Palavras-chave: PCB; Biogéochimie; Contamination; Écotoxicologie; PCBs; Biogeochemistry; Contamination; Ecotoxicology. Ano: 1990 URL: http://archimer.ifremer.fr/doc/00148/25954/24045.pdf ISSR as new markers for genetic characterization and evaluation of relationships among phytoplankton ArchiMer Bornet, Benjamin; Antoine, Elisabeth; Bardouil, Michele; Marcaillou-le Baut, Claire. In order to increase the molecular tools and markers needed for the identification of phytoplankton species, the inter simple sequence repeat ( ISSR) fingerprinting was adapted to micro-algae and its use in genetic analysis was demonstrated. Twelve strains, 6 Alexandrium, 4 Pseudo-nitzschia, 1 Skeletonema and 1 Tetraselmis were analysed for the first time with ISSR amplifications. The patterns were highly polymorphic and very reproducible. The 6 primers gave 223 polymorphic markers that clearly and easily distinguished all 12 strains ( mainly toxic ones) and gave 187 polymorphic markers among the Alexandrium and the Pseudo-nitzschia species. ISSR amplifications also indicated a large occurrence of simple sequence repeat ( SSR) in phytoplankton genomes,... Tipo: Text Palavras-chave: Tetraselmis; Skeletonema; Pseudo nitzschia; ISSR; Genetic characterization and diversity; Fingerprints; Alexandrium. Ano: 2004 URL: http://archimer.ifremer.fr/doc/2004/publication-516.pdf Nuisances et intoxications causées en France par le phytoplancton et les "efflorescences" marines - Synthèse préliminaire ArchiMer Sournia, A.; Belin, Catherine; Berland, B.; Erard-le Denn, Evelyne; Grzebyk, Daniel; Marcaillou-le Baut, Claire; Lassus, Patrick; Partensky, F.. Les intoxications humaines résultant de la consommation de coquillages sont connues en France depuis plusieurs siècles. On peut supposer que la cause principale a d'abord été d'origine bactériologique, eu égard aux conditions de transport et à l'absence de contrôles de salubrité dans le passé. Quoi qu'il en soit, il faut compter aujourd'hui avec une autre origine, à savoir les proliférations de certaines algues unicellulaires planctoniques (phytoplancton), qui causent dans notre pays jusqu'à plusieurs milliers d'intoxications par an. Soulignons que la France a été jusqu'ici largement épargnée, puisque d'autres pays comptabilisent des dizaines ou centaines de décès depuis le début du siècle. On vient toutefois de découvrir la présence dans nos eaux côtières... Tipo: Text Ano: 1990 URL: http://archimer.ifremer.fr/doc/00069/18017/15569.pdf Azaspiracid accumulation, detoxification and biotransformation in blue mussels (Mytilus edulis) experimentally fed Azadinium spinosum ArchiMer Jauffrais, Thierry; Marcaillou-le Baut, Claire; Herrenknecht, Christine; Truquet, Philippe; Sechet, Veronique; Nicolau, Elodie; Tillmann, Urban; Hess, Philipp. Azadinium spinosum (Elbrächter and Tillmann), a small marine dinoflagellate, has been recently described as a de novo producer of azaspiracid-1 and -2 (AZA1 and -2) diarrhoeic toxins. A culture of A. spinosum was established in our laboratory and optimised for pilot-scale production of this organism, to evaluate and understand AZA1 and -2 accumulation and biotransformation in blue mussels (Mytilus edulis) fed with A. spinosum. Adult mussels were continuously exposed to A. spinosum over 1 week in 160 L cylindrical conical tanks. Three different diets were tested for contamination: 5000, 10 000 cells mL−1 of A. spinosum and a mixture of 5000 cells mL−1 of A. spinosum with 5000 cells mL−1 of Isochrysis aff. galbana (T-Iso, CCAP 927/14). During the subsequent... Tipo: Text Palavras-chave: Azaspiracid; Azadinium spinosum; Marine biotoxins; AZA; Tissue distribution; Histology; Bivalve molluscs; Liquid chromatography coupled to tandem mass spectrometry. Ano: 2012 URL: http://archimer.ifremer.fr/doc/00088/19877/17566.pdf Etude de pré-validation du test de cytodétection des toxines diarrhéiques (acide okadaïque) dans les coquillages contaminés ArchiMer Le Gal, Dominique; Marcaillou-le Baut, Claire. A cytodetection test of diarrhoeic phycotoxins was developped by both IFREMER and Nantes University. Its principle is based on cell morphological changes of KB strain, induced by inhibition of protein-phosphatases involved in cytoskeleton building. This test has been shown sensitive, fast and specific for protein phosphatase inhibitors like diarrhoeic toxins (specialy okadaic acid in France). It shows a high repeatability and reproducibility with pure toxin for the cell strain is highly stable (minimal active concentration or MAC = 125 ng OA.ml-1) In order to evaluate the efficiency oftransfering.the method to coastallaboratories, the assay was subjected to a prevalidation study. The sampling, consisting of five species of shellfish, was carried out during... Tipo: Text Palavras-chave: Phycotoxine; Acide okadaïque; Test de cytodétection; Prévalidation; Phycotoxin; Okadaïc acid; Cytodetection assay; Prevalidation. Ano: 2001 URL: http://archimer.ifremer.fr/doc/00138/24909/23002.pdf COMSAUMOL (maintien de la COMmercialisation par la SAUvegarde et la détoxication des MOLlusques). Etude 2008-2010. Rapport final ArchiMer Haure, Joel; Hussenot, Jerome; Buzin, Florence; Dupuy, Beatrice; Palvadeau, Hubert; Penisson, Christian; Papin, Mathias; Nourry, Max; Lassus, Patrick; Marcaillou-le Baut, Claire; Mondeguer, Florence; Royer, F.; Amzil, Zouher; Belin, Catherine; Cardinal, Mireille; Le Grel, L.; Le Bihan, V.; Jaouen, P.; Massé, A.; Castaing, Jean-baptiste; Sabiri, Ne.; Pontié, M.. La contamination des denrées d’origine marine par des toxines algales (phycotoxines) a pris depuis quelques années une importance considérable. Ce phénomène est largement lié à l’augmentation du nombre de zones géographiques touchées ainsi qu’à la diversification des espèces toxinogènes et à l’identification de nouveaux composés toxiques. Les données épidémiologiques sont cependant encore peu nombreuses car elles sont liées à la mise en place de contrôles systématiques récents. L’Union Européenne a établi un Laboratoire Communautaire de référence pour les phycotoxines, situé à Vigo (Espagne) qui coordonne les activités des laboratoires Nationaux de références correspondants (en France c’est le LNR Phycotoxines de l’AFSSA qui assure cette mission). C’est... Tipo: Text Ano: 2011 URL: http://archimer.ifremer.fr/doc/00092/20277/17922.pdf Registros recuperados: 24 Primeira ... 1 2 ... Última

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