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| Registros recuperados: 49 | |
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| Gaydou,Luisa; Bertuzzi,Romina; Moretti,Edgardo. |
| El estrés tiene alta prevalencia en el mundo; una de sus causas es la sepsis. Durante la misma, se liberan citoquinas que activan el eje hipotálamo-hipofiso suprarrenal (HHS) elevándose el cortisol y proteínas de fase aguda. El objetivo de este trabajo fue analizar el efecto de la sepsis sobre el eje HHS a través del cortisol, y asociarlo con interleuquina 1 beta (IL1-beta) y proteína C reactiva (PCR). Se dosó cortisol por electroquimioluminscencia, PCR por inmunoturbidimetría e IL1-beta por ELISA en sueros de pacientes sépticos (S, n=40) y no sépticos (NS, n=21). El cortisol fue significativamente mayor al valor de corte (VC), establecido mediante curva ROC, en el 63% de pacientes S, y sólo en el 14% de NS (OR: 10,0; IC: 2,5 - 39,7; p<0,05). La PCR... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Estrés; Sepsis; Cortisol; Interleuquina 1beta; Proteína C reactiva. |
| Ano: 2009 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572009000300002 |
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| GIUSTINA,AMANDA D.; DANIELSKI,LUCINÉIA G.; NOVOCHADLO,MICHELE M.; GOLDIM,MARIANA P.S.; JOAQUIM,LARISSA; METZKER,KIUANNE L.L.; CARLI,RAQUEL JACONI DE; DENICOL,TAIS; CIDREIRA,THAINA; VIEIRA,THAYNAN; PETRONILHO,FABRICIA. |
| Abstract Abstract: Sepsis is a life-threatening organ dysfunction induced by a disrupted host response to infecting pathogens. Inflammation and oxidative stress are intrinsically related to sepsis progression and organ failure. Vitamin B6 is an important cellular cofactor for metabolic processes and has anti-inflammatory and antioxidant properties. We aimed at evaluating the effect of vit B6 on inflammation and oxidative stress markers in the liver and lung of rats subjected to a relevant animal model of polymicrobial sepsis. Adult male Wistar rats were submitted to cecal ligation and perforation model and immediately after sepsis induction, vit B6 was administered as a single dose (600 mg/kg, subcutaneous). Twenty-four hours later, the lung and liver... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sepsis; Vitamin B6; Oxidative stress; Antioxidant. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000700627 |
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| Colombo,Arnaldo L.; Janini,Mario; Salomão,Reinaldo; Medeiros,Eduardo A. S.; Wey,Sergio B.; Pignatari,Antonio C. C.. |
| Several epidemiological changes have occurred in the pattern of nosocomial and community acquired infectious diseases during the past 25 years. Social and demographic changes possibly related to this phenomenon include a rapid population growth, the increase in urban migration and movement across international borders by tourists and immigrants, alterations in the habitats of animals and arthropods that transmit disease, as well as the raise of patients with impaired host defense abilities. Continuous surveillance programs of emergent pathogens and antimicrobial resistance are warranted for detecting in real time new pathogens, as well as to characterize molecular mechanisms of resistance. In order to become more effective, surveillance programs of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Emerging infectious diseases; HIV; AIDS; Candidemia; Antimicrobial resistance; Bacteremia; Sepsis; Nosocomial infectious. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300020 |
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| Couto,Renato C.; Barbosa,José A. A.; Pedrosa,Tânia M.G.; Biscione,Fernando M.. |
| Late-onset sepsis (LOS) (i.e., sepsis in a neonate after 72 hours of life) is associated with high mortality and significantly prolonged antibiotic exposure and hospital stay in neonates admitted to intensive care units (ICU). In this study, we assessed the reliability of serum C-reactive protein (CRP) as a determinant of antimicrobial treatment duration of LOS. From January 1996 to December 2002, all consecutive infants aged <28 days admitted to a single medical-surgical ICU and diagnosed with primary LOS were enrolled in a prospective, intervention trial with historical controls. Only blood culture-positive LOSs were included. Exclusion criteria were: age >28 days at diagnosis of LOS, development of site-specific infection, and central venous... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: C-reactive protein; Newborn; Neonatal intensive care units; Sepsis; Antibiotics. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200015 |
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| Bilevicius,Elizabeth; Dragosavac,Desanka; Dragosavac,Sanja; Araújo,Sebastião; Falcão,Antonio L.E.; Terzi,Renato G.G.. |
| Multiple organ failure (MOF) is the main cause of death in ICUs, especially affecting septic patients. It is strongly related to number of systems with failure, type of system involved, risk factors such as age, previous chronic diseases, delayed or inadequate resuscitation, persistent infection, immune suppression, and others. The prognoses is worse for patients rather than in elective or emergency surgical patients. The objective of this article is to provide data from our university teaching hospital ICU related to the incidence of septic patients, the distribution of MOF, and distribution of failure among each of the organs. The mortality rate, relationship between mortality and age, and mortality and types of organs affected were evaluated. The main... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: APACHE II; Sepsis; Multiple organ failure. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000300001 |
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| Romanelli,Roberta Maia de Castro; Anchieta,Lêni Márcia; Carvalho,Elaine Alvarenga de Almeida; Silva,Lorena Ferreira da Glória e; Nunes,Rafael Viana Pessoa; Mourão,Paulo Henrique; Clemente,Wanessa Trindade; Bouzada,Maria Cândida Ferrarez. |
| BACKGROUND: Healthcare Associated Infections constitute an important problem in Neonatal Units and invasive devices are frequently involved. However, studies on risk factors of newborns who undergo surgical procedures are scarce. OBJECTIVE: To identify risk factors for laboratory-confirmed bloodstream infection in neonates undergoing surgical procedures. METHODS: This case-control study was conducted from January 2008 to May 2011, in a referral center. Cases were of 21 newborns who underwent surgery and presented the first episode of laboratory-confirmed bloodstream infection. Control was 42 newborns who underwent surgical procedures without notification of laboratory-confirmed bloodstream infection in the study period. Information was obtained from the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Newborn intensive care units; Infection control; Surgery; Sepsis. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400400 |
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| Abboud,C. S.; Vargas,J; Ferraretto,I.. |
| We report a case of leptospirosis that occurred after elective surgery involving tendon transfer and shoulder arthroscopy. The disease mimicked hospital infection after orthopedic surgery and was at first misdiagnosed as post-operative sepsis. The patient was 60 year old female that developed sepsis with hypotension, shock, bleeding, jaundice and renal insufficiency 4 hours after surgery. Shock treatment procedures were performed and broad spectrum antibiotic therapy was used with coverage for bacteria acquired in hospitals. A careful investigation was carried out by the Hospital Infection Control Service in search of the possible source of the infection. After clinical evaluation by a specialist in infectious diseases, the hypothesis of leptospirosis was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Leptospirosis; Sepsis; Orthopedic surgery. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000500006 |
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| Silva,José Bruno Nunes Ferreira da; Oliveira,Samara Kelly Mendonça de; Campos,Ingrid Araújo; Carvalho-Júnior,Carlson Helder Reis de; Coutinho,Thiago da Cunha; Silva,Teresinha Gonçalves. |
| BACKGROUND: Sepsis is a systemic inflammation associated with infection caused by pathogenic micro-organisms with high mortality rates. OBJECTIVE: In this study, we investigated the protective effect of Propionibacterium acnes-killed against polymicrobial sepsis induced by cecal ligation and puncture. METHODS: The mice were treated by intramuscular route in 1, 3, 5, and 7 days before the cecal ligation and puncture induction. The control group animals received vehicle (saline solution 0.9%) and the animals of the treated group received the P. acnes-killed (0.4 mg/animal). After anesthesia, midline laparotomy was performed with exposure of cecum followed by ligature and one transverse perforation of the same, with a 18 G needle, for induction of lethal... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Propionibacterium acnes; Immunomodulation; Sepsis; Cytokines. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000100004 |
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| Diament,Décio; Colombari,Fernando; Cypriano,Adriana Serra; Lisboa,Luis Fernando; dos Santos,Bento Fortunato Cardoso; Cendoroglo Neto,Miguel; Serpa Neto,Ary; Silva,Eliezer. |
| Abstract Objective The aim of the present study was to obtain information about deaths due to sepsis in São Paulo from 2004 to 2009 and their relationship with geographical distribution. Methods Causes of death, both main and secondary, were defined according to the codes of the International Classification of Disease version 10 (ICD-10) contained in the database. Sepsis, septic shock, multiple organ failure, pneumonia, urinary tract infection, peritonitis and other intraabdominal infections, skin and soft tissue infections (including surgical wound infection) and meningitis were considered as immediate cause of death or as the condition leading to the immediate cause of death related or associated to sepsis. Results In the analyzed period, there was a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sepsis; Mortality; Infection; Georeferencing. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000200149 |
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| Kauss,IAM; Grion,Cintia MC; Cardoso,LTQ; Anami,EHT; Nunes,LB; Ferreira,GL; Matsuo,T; Bonametti,AM. |
| OBJECTIVES: The objective of this study was to estimate disease incidence and mortality rate of sepsis in a tertiary public hospital. METHODS: Patients admitted to the Intensive Care Unit (ICU) in 2004 and 2005 were monitored for sepsis using an observational longitudinal study design. Patients were monitored daily for diagnostic criteria of sepsis, according to ACCP/SCCM Consensus Conference criteria, until either death or hospital discharge. RESULTS: During the study, we analyzed 1,179 patients. Systemic Inflammatory Response Syndrome (SIRS) was present in 1,048 (88.9%) patients on admission, and was associated with infection in 554 (47.0%) patients. Of these, sepsis was diagnosed in 30 (2.5%) patients, while severe sepsis was diagnosed in 269 (22.8%)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sepsis; Incidence; Mortality; Epidemiology. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300011 |
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| Registros recuperados: 49 | |
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