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Mesothelin as a biomarker for ovarian carcinoma: a meta-analysis Anais da ABC (AABC)
MADEIRA,KRISTIAN; DONDOSSOLA,EDUARDO R.; FARIAS,BRUNA F. DE; SIMON,CARLA S.; ALEXANDRE,MARIA C.M.; SILVA,BRUNO R.; ROSA,MARIA INÊS.
The objective of this work was to estimate the accuracy of mesothelin as a biomarker for ovarian cancer. A quantitative systematic review was performed. A comprehensive search of the Medline, LILACS, SCOPUS, Embase, Cochrane Central Register of Controlled Trials, Biomed Central, and ISI Web of Science databases was conducted from January 1990 to June 2015. For inclusion in this systematic review, the papers must have measured mesothelin levels in at least two histological diagnoses; ovarian cancer (borderline or ovarian tumor) vs. benign or normal ovarian tissue. For each study, 2 x 2 contingency tables were constructed. We calculated the sensitivity, specificity and diagnostic odds ratio. The verification bias was performed according to QUADAS-2....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ovarian tumors; Mesothelin; Meta-analysis; Biomarker; Statistical.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000300923
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Accuracy of immunoglobulin M and immunoglobulin A of saliva in early diagnosis of dengue: Systematic Review and Meta-analysis Anais da ABC (AABC)
COLONETTI,TAMY; ROCHA,BELISE V.E.; GRANDE,ANTÔNIO J.; ALEXANDRE,MARIA C.M.; DONDOSSOLA,EDUARDO R.; MADEIRA,KRISTIAN; ROSA,MARIA I..
ABSTRACT The objective of the study was to conduct a systematic review to synthesize the current evidence on the accuracy of IgM and IgA to early diagnosis the dengue virus. The review protocol was registered at PROSPERO (CRD 42015024808). We searched for studies in the following electronic database from 1990 to January 2018. The search identified 3507 studies. Five studies were included for quantitative analysis. Three studies included evaluations of salivary IgM provided a sensitivity of 86% and specificity of 93%. Two studies included evaluating of IgA salivary showed a combined sensitivity of 69% and a combined specificity of 98%. Despite the results found and the low methodological quality of the studies included in the meta-analysis it is still soon...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunoglobulin M; Immunoglobulin A; Antibodies; Dengue virus; Diagnosis..
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000603147
Registros recuperados: 2
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