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ASSIS,FELIPE V. DE; SIQUEIRA,FLÁVIA L.; GONÇALVES,ISABELA E.; LACERDA,RAFAEL P.; NASCIMENTO,RAFAELA A.; ARAÚJO,STHÉFANE G.; ANDRADE,JÉSSICA T.; HERRERA,KARINA M.S.; LIMA,LUCIANA A.R.S.; FERREIRA,JAQUELINE M.S.. |
ABSTRACT The antibacterial activity of plant extracts of the Lamiaceae family was evaluated against clinical isolates of multi-resistant Gram-negative bacteria by broth microdilution technique. Promising results were obtained considering that all extracts were active for at least two bacterial species with MIC ranging from 0.5 to 2.0 mg/mL. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial; Clinical isolates; Lamiaceae extracts; Multidrug-resistant. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401665 |
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PINTO,MARIA E.A.; ARAÚJO,STHÉFANE G.; MORAIS,MARCELA I.; SÁ,NÍVEA P.; LIMA,CAROLINE M.; ROSA,CARLOS A.; SIQUEIRA,EZEQUIAS P.; JOHANN,SUSANA; LIMA,LUCIANA A.R.S.. |
ABSTRACT Fatty acid methyl esters (FAMEs) were obtained from vegetable oils of soybean, corn and sunflower. The current study was focused on evaluating the antifungal activity of FAMEs mainly against Paracoccidioides spp., as well as testing the interaction of these compounds with commercial antifungal drugs and also their antioxidant potential. FAMEs presented small IC50 values (1.86-9.42 μg/mL). All three FAMEs tested showed antifungal activity against isolates of Paracoccidioides spp. with MIC values ranging from 15.6-500 µg/mL. Sunflower FAMEs exhibited antifungal activity that extended also to other genera, with an MIC of 15.6 μg/mL against Candida glabrata and C. krusei and 31.2 μg/mL against C. parapsilosis. FAMEs exhibited a synergetic effect with... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antifungal; Antioxidant; Fatty acid methyl esters; Vegetable oils. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000401671 |
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