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Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis BJID
Abboud,Cely Saad; Rao,Gauri G.; Souza,Ercilia E.; Zavascki,Alexandre P.; Kiffer,Carlos.
ABSTRACT A retrospective cohort study, were evaluated: polymyxin B plus aminoglycosides or polymyxin B plus other antibiotics. Any degree of acute kidney injury occurred in 26 (86.6%) patients. The median time to acute kidney injury was 6.0 (95% CI 3–14) days in the polymyxin-aminoglycoside containing regimen group, against 27.0 (95% CI 6–42) days in the polymyxin with other antimicrobial combinations group (p = 0.03). Polymyxin B with aminoglycosides group progressed faster to any degree of renal dysfunction.
Tipo: Info:eu-repo/semantics/other Palavras-chave: AKI; CRE; Polymyxins; Aminoglicosides.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000100051
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Fatal case of donor-derived colistin-resistant carbapenemase-producing Klebsiella pneumoniae transmission in cardiac transplantation BJID
Galvão,Lisia Miglioli; Oliveira,Anna Paula Romero de; Ibanês,Aline Santos; Monteiro,Jussimara; Inoue,Fernanda; Dantas,Daniel Chagas; Sanchez,Flavio; Santos,Daniel Wagner; Abboud,Cely Saad.
ABSTRACT Herein we report a fatal case of donor-derived transmission of XDR-resistant carbapenemase-producing Klebsiella pneumoniae (KPC-Kp) in cardiac transplantation. A 59-year-old male patient with non-obstructive hypertrophic cardiomyopathy underwent heart transplantation. On day 5 post-operation, blood cultures from the donor were positive for colistin-resistant carbapenemase-producing K. pneumoniae (ColR KPC-Kp) susceptible only to amikacin. Recipient blood cultures were also positive for ColR KPC-Kp with the same sensitivity profile as the donor isolate with an identical PFGE pattern. The patient was treated with double-carbapenems and amikacin. The patient evolved to pericarditis, osteomyelitis, and pulmonary necrosis, all fragment cultures...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Cardiac transplantation; Klebsiella pneumoniae; Donor-derived infection; Carbapenem-resistant.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300235
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Nosocomial infections caused by Elizabethkingia meningoseptica: an emergent pathogen BJID
Pereira,Graziella H.; Garcia,Doroti de Oliveira; Abboud,Cely Saad; Barbosa,Vera Lucia de Barros; Silva,Paulo Sérgio Lucas da.
We hereby describe the clinical and epidemiological features and, outcomes of nine patients with Elizabethkingia meningoseptica infections in two hospitals over a 2-year period. All infections caused by this pathogen were nosocomial, or healthcare associated infections, in hemodialysis settings whereas none was correlated with hospital outbreaks.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Elizabethkingia meningoseptica; Nosocomial infections; Bloodstream infections.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500015
Registros recuperados: 3
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