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| Abdelbaset, E. Abdelbaset; Fox, Barbara A.; Karram, Mohamed H.; Abd Ellah, Mahmoud R.; Bzik, David J.; Igarashi, Makoto. |
| In the asexual stages, Toxoplasma gondii stage converts between acute phase rapidly replicating tachyzoites and chronic phase slowly dividing bradyzoites. Correspondingly, T. gondii differentially expresses two distinct genes and isoforms of the lactate dehydrogenase enzyme, expressing LDH1 exclusively in the tachyzoite stage and LDH2 preferentially in the bradyzoite stage. LDH catalyzes the interconversion of pyruvate and lactate in anaerobic growth conditions and is utilized for energy supply, however, the precise role of LDH1 and LDH2 in parasite biology in the asexual stages is still unclear. Here, we investigated the biological role of LDH1 and LDH2 in the asexual stages, and the vaccine strain potential of deletion mutants lacking LDH1, LDH2, or both... |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4451 |
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| Pumidonming, Wilawan; Salman, Doaa; Gronsang, Dulyatad; Abdelbaset, E. Abdelbaset; Sangkaeo, Khamphon; Kawazu, Shin-ichiro; Igarashi, Makoto. |
| Gastrointestinal zoonotic helminths of dogs and cats have a public health concern worldwide. We investigated the prevalence of gastrointestinal helminths of zoonotic significance in dogs and cats in lower Northern Thailand and utilized molecular tools for species identification of hookworms and Opisthorchis viverrini. Fecal samples of 197 dogs and 180 cats were collected. Overall prevalence of infection using microscopy was 40.1% in dogs and 33.9% in cats. Helminth infection found in both dogs and cats included hookworms, Spirometra spp., Taenia spp., Toxocara spp., 0. viverrini, Strongyloides spp. and Trichuris spp. Hookworms were the most common helminth in dogs, while Spirometra spp. were the most prevalent in cats. Among hookworm infection in dogs and... |
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Palavras-chave: Cat; Dog; Gastrointestinal helminth; Thailand; Zoonotic parasite. |
| Ano: 2016 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4452 |
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