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Histological changes of the liver and metabolic correlates in ewes with pregnancy toxemia Arq. Bras. Med. Vet. Zootec.
Cal,L.; Borteiro,C.; Benech,A.; Rodas,E.; Abreu,M.N.; Cruz,J. C.; González Montaña,J. R..
The histological changes of the liver in ewes with pregnancy toxemia were characterized. Ten ewes were fed on grass ad libitum, and another ten were starved from day 130 of pregnancy for up to four days. Liver puncture biopsies were performed at days 70, 100, 130, and 140 of pregnancy, and at day 45 in postpartum. Seric hydroxybutyrate (HB), non-esterified fatty acids (NEFA), aspartate aminotransferase, and alkaline phosphatase were dosed. Histological preparations revealed similar incidence and intensity of mild liver steatosis in both groups at day 130. Starved ewes become toxemic (as indicated by HB), and at day 140 exhibited more severe injury in a higher proportion (9/9 vs. 4/10; P<0.01). Almost all of them (7/9) had large amounts of small lipid...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ewe; Liver biopsy; Microvesicular steatosis; Pregnancy toxemia.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352009000200004
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