| The role of inflammation in causation of both Diabetes and its complications has gained acceptance. Initially, hyperglycemia was thought to be the factor causing inflammation, but recently, obesity has gained attraction as probable cause of inflammation. We have studied the levels of markers of inflammation in Diabetic patients, with uncontrolled hyperglycemia, before and after treatment. The results indicate that hyperglycemia significantly causes increase in inflammatory markers like TNF-α and IL-6, which further contribute to pathogenesis of Diabetes mellitus type 2 as well as its complications such as atherosclerosis and neuropathy. |
