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| Padulla,Susimary Aparecida Trevizan; Azoubel,Reinaldo; Bonfim,Mariana Rotta; Accioly,Marilita Falángola; Camargo Filho,José Carlos Silva; Padovani,João Armando; Brandao,Antonio Carlos; Souza,Dorotéia Rossi Silva. |
| Physical exercise and statins, recommended interventions to dyslipidaemia treatment, are independently related to cardiomyocytes alterations, characterized by miocardic hypertrophy and apoptosis, respectively. Thus, the objective of the present study was to analyze the effects of statin and aerobic physical exercise association in the morphometric parameters of cardiac cell nucleus. 40 male rats adults were divided into four groups: exercised (DE); sedentary (DS), exercised and statin use (DES); sedentary and statin use (DSS). The animals received during the whole experimental period a hiperlipidic diet added 20% of coconut oil and 1.25% of cholesterol; after 30 days of its ingestión, a blood collection was made to verify the dyslipidaemia. Simvastatin (20... |
| Tipo: Journal article |
Palavras-chave: Hydroxymethylglutaryl-CoA Reductase Inhibitors; Exercise; Cardiomyocite nuclei. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000100015 |
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