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| Carvalho, Raquel N.; Arukwe, Augustine; Ait-aissa, Selim; Bado-nilles, Anne; Balzamo, Stefania; Baun, Anders; Belkin, Shimshon; Blaha, Ludek; Brion, Francois; Conti, Daniela; Creusot, Nicolas; Essig, Yona; Ferrero, Valentina E. V.; Flander-putrle, Vesna; Furhacker, Maria; Grillari-voglauer, Regina; Hogstrand, Christer; Jonas, Adam; Kharlyngdoh, Joubert B.; Loos, Robert; Lundebye, Anne-katrine; Modig, Carina; Olsson, Per-erik; Pillai, Smitha; Polak, Natasa; Potalivo, Monica; Sanchez, Wilfried; Schifferli, Andrea; Schirmer, Kristin; Sforzini, Susanna; Sturzenbaum, Stephen R.; Softeland, Liv; Turk, Valentina; Viarengo, Aldo; Werner, Inge; Yagur-kroll, Sharon; Zounkova, Radka; Lettieri, Teresa. |
| The risk posed by complex chemical mixtures in the environment to wildlife and humans is increasingly debated, but has been rarely tested under environmentally relevant scenarios. To address this issue, two mixtures of 14 or 19 substances of concern (pesticides, pharmaceuticals, heavy metals, polyaromatic hydrocarbons, a surfactant, and a plasticizer), each present at its safety limit concentration imposed by the European legislation, were prepared and tested for their toxic effects. The effects of the mixtures were assessed in 35 bioassays, based on 11 organisms representing different trophic levels. A consortium of 16 laboratories was involved in performing the bioassays. The mixtures elicited quantifiable toxic effects on some of the test systems... |
| Tipo: Text |
Palavras-chave: Bioassays; Effects; Mixtures; Ecotoxicology; Biomarkers. |
| Ano: 2014 |
URL: https://archimer.ifremer.fr/doc/00499/61115/64667.pdf |
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| Di Paolohttps://w3.ifremer.fr/archimer-admin/author.jsp#, Carolina; Ottermanns, Richard; Keiter, Steffen; Ait-aissa, Selim; Bluhm, Kerstin; Brack, Werner; Breitholtz, Magnus; Buchinger, Sebastian; Carere, Mario; Chalon, Carole; Cousin, Xavier; Dulio, Valeria; Escher, Beate I.; Hamers, Timo; Hilscherova, Klara; Jarque, Sergio; Jonas, Adam; Maillot-marechal, Emmanuelle; Marneffe, Yves; Mai Thao Nguyen,; Pandard, Pascal; Schifferli, Andrea; Schulze, Tobias; Seidensticker, Sven; Seiler, Thomas-benjamin; Tang, Janet; Van Der Oost, Ron; Vermeirssen, Etienne; Zounkova, Radka; Zwart, Nick; Hollert, Henner. |
| Bioassays are particularly useful tools to link the chemical and ecological assessments in water quality monitoring. Different methods cover a broad range of toxicity mechanisms in diverse organisms, and account for risks posed by non-target compounds and mixtures. Many tests are already applied in chemical and waste assessments, and stakeholders from the science-police interface have recommended their integration in regulatory water quality monitoring. Still, there is a need to address bioassay suitability to evaluate water samples containing emerging pollutants, which are a current priority in water quality monitoring. The presented interlaboratory study (ILS) verified whether a battery of miniaturized bioassays, conducted in 11 different laboratories... |
| Tipo: Text |
Palavras-chave: Triclosan; Acridine; 17 alpha-ethinylestradiol; 3-Nitrobenzanthrone; Organism-level toxicity; Mechanism-specific toxicity. |
| Ano: 2016 |
URL: http://archimer.ifremer.fr/doc/00347/45846/45498.pdf |
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| David, Arthur; Gomez, Elena; Ait-aissa, Selim; Bachelot, Morgane; Rosain, David; Casellas, Claude; Fenet, Helene. |
| In this study, the distribution of organic contaminants was investigated in the particular context of three Mediterranean coastal lagoons, where pollution input was hypothesised to come mainly from sediments resuspension. Mussels and semi-permeable membrane devices (SPMDs) were exposed to the water column for one month and then their content in estrogen-, benzo[ a] pyrene-and dioxin-like substances as well as polycyclic aromatic hydrocarbons (PAH), polychlorinated biphenyls and alkylphenols was determined with biological and chemical analyses. PAH concentration was high in sediments (up to 1028 ng g(-1) dry weight), however the aqueous PAH concentrations estimated from SPMD data could be considered below the levels inducing adverse effects according to the... |
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| Ano: 2010 |
URL: http://archimer.ifremer.fr/doc/00009/11991/9062.pdf |
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