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| Moriel,P.; Sevanian,A.; Ajzen,S.; Zanella,M.T.; Plavnik,F.L.; Rubbo,H.; Abdalla,D.S.P.. |
| The objective of the present study was to identify disturbances of nitric oxide radical (·NO) metabolism and the formation of cholesterol oxidation products in human essential hypertension. The concentrations of·NO derivatives (nitrite, nitrate, S-nitrosothiols and nitrotyrosine), water and lipid-soluble antioxidants and cholesterol oxides were measured in plasma of 11 patients with mild essential hypertension (H: 57.8 ± 9.7 years; blood pressure, 148.3 ± 24.8/90.8 ± 10.2 mmHg) and in 11 healthy subjects (N: 48.4 ± 7.0 years; blood pressure, 119.4 ± 9.4/75.0 ± 8.0 mmHg).Nitrite, nitrate and S-nitrosothiols were measured by chemiluminescence and nitrotyrosine was determined by ELISA. Antioxidants were determined by reverse-phase HPLC and cholesterol oxides... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nitrotyrosine; S-nitrosothiols; Nitrate; Oxidized LDL; Lipid peroxidation; Endothelin-1. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001100007 |
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| Plavnik,F.L.; Ajzen,S.; Kohlmann Jr.,O.; Tavares,A.; Zanella,M.T.; Ribeiro,A.B.; Ramos,O.L.. |
| The aim of this study was to analyze the thickness of the intima-media complex (IMC) using a noninvasive method. The carotid and femoral common arteries were evaluated by noninvasive B-mode ultrasound in 63 normotensive and in 52 hypertensive subjects and the thickness of the IMC was tested for correlation with blood pressure, cardiac structures and several clinical and biological parameters. The IMC was thicker in hypertensive than in normotensive subjects (0.67 ± 0.13 and 0.62 ± 0.16 vs 0.54 ± 0.09 and 0.52 ± 0.11 mm, respectively, P<0.0001). In normotensive patients, the simple linear regression showed significant correlations between IMC and age, body mass index and 24-h systolic blood pressure for both the carotid and femoral arteries. In... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Arterial thickness; B-mode ultrasound; 24-ABPM; Cardiac structures. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000100008 |
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| Gandolpho,L.; Sevillano,M.; Barbieri,A.; Ajzen,S.; Schor,N.; Ortiz,V.; Heilberg,I.P.. |
| Forty-seven patients with unilateral obstructive calculi (12 males and 35 females) were submitted to 99mTc-diethylene triamine pentaacetic acid (DTPA) or 99mTc-dimercaptosuccinic acid (DMSA) scans for assessment of renal function. The scans revealed unilateral functional deficit in 68 and 66% of the patients, respectively. A calculus size of 1.1 to 2.0 cm was significantly associated with deficit detected by DTPA, but duration of obstruction and calculus localization were not. After relief of the obstruction, the mean percent renal function of the affected kidney was found to be significantly increased from 25 ± 12% to 29 ± 12% in DTPA and from 21 ± 15% to 24 ± 12% in DMSA. Initial Doppler ultrasonography performed in 35 patients detected an increased... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Urinary tract obstruction; Obstructive calculi; DTPA and DMSA scans; Resistive index; Doppler ultrasonography. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600007 |
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