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	Provedor de dados Genet. Mol. Biol. (1) Autor Akkarapatumwong,Varaporn (1) Eurwilaichitr,Lily (1) Keskanokwong,Thitima (1) Kittanakom,Saranya (1) Limjindaporn,Thawornchai (1) Wongthida,Phonphimon (1) Yenchitsomanus,Pa-thai (1) Mais... Palavra-chave Kanadaptin (1) Kidney anion exchanger 1 (1) Yeast two-hybrid system (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2006 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Analysis of the interaction between human kidney anion exchanger 1 and kanadaptin using yeast two-hybrid systems Genet. Mol. Biol. Wongthida,Phonphimon; Akkarapatumwong,Varaporn; Limjindaporn,Thawornchai; Kittanakom,Saranya; Keskanokwong,Thitima; Eurwilaichitr,Lily; Yenchitsomanus,Pa-thai. Kidney anion exchanger adaptor protein (Kanadaptin) is a protein which interacts with the cytoplasmic N-terminal domain of kidney anion exchanger 1 (kAE1) and was first detected in mice using the yeast two-hybrid system and was also found to co-localize with kAE1 in rabbit a-intercalated cells. Impaired trafficking of human kAE1 can result in the kidney disease-distal renal tubular acidosis (dRTA), and defective interaction between human kAE1 and kanadaptin may cause this trafficking impairment and be the basis for dRTA pathogenesis. However, it is unknown whether kAE1 can really interact with kanadaptin in humans. We have thus investigated the interaction between human kAE1 and human kanadaptin by using both Gal4 and LexA yeast two-hybrid systems. It was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Kidney anion exchanger 1; Kanadaptin; Yeast two-hybrid system. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000100003 Registros recuperados: 1 Primeira ... 1 ... Última

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