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Osteoinductive Potential of the rhBMP-2 in Soft Tissues International Journal of Morphology
Issa,Joao Paulo Mardegan; Nascimento,Cássio do; Barbosa,Rodrigo Edson dos Santos; Iyomasa,Mamie Mizusaki; Albuquerque Junior,Rubens Ferreira de.
The rhBMP-2 is an osteoinductive protein used in the reconstructive with the objective to create newly formed bone. The aim of this study was to confirm the rhBMP-2 osteoinductive capability, when implanted in soft tissues. The results showed that the protein used in this study is highly osteoinductive
Tipo: Journal article Palavras-chave: Bone repair; RhBMP-2; Osteoinduction; Soft tissue.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000100018
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Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles International Journal of Morphology
Issa,Joáo Paulo Mardegan; Nascimento,Cássio do; Sato,Sandra; Barbosa,Rodrigo Edson Santos; Benetti,Emerson Toffanello; Albuquerque Junior,Rubens Ferreira de.
The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between them
Tipo: Journal article Palavras-chave: Optical densitometry; RhBMP-2; Monoolein; Bone defects.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200018
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