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| Asad,Nasser Ribeiro; Asad,Lidia Maria Buarque Oliveira; Almeida,Carlos Eduardo Bonacossa de; Felzenszwalb,Israel; Cabral-Neto,Januário Bispo; Leitão,Alvaro Costa. |
| Hydrogen peroxide is an important reactive oxygen species (ROS) that arises either during the aerobic respiration process or as a by-product of water radiolysis after exposure to ionizing radiation. The reaction of hydrogen peroxide with transition metals imposes on cells an oxidative stress condition that can result in damage to cell components such as proteins, lipids and principally to DNA, leading to mutagenesis and cell death. Escherichia coli cells are able to deal with these adverse events via DNA repair mechanisms, which enable them to recover their genome integrity. These include base excision repair (BER), nucleotide excision repair (NER) and recombinational repair. Other important defense mechanisms present in Escherichia coli are OxyR and SosRS... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hydrogen peroxide; Cross-adaptive response; Lethal synergism; Copper and iron. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000200026 |
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