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| Mendes,Bruno Melo; Almeida,Iassudara Garcia de; Trindade,Bruno Machado; Fonseca,Telma Cristina Ferreira; Campos,Tarcísio Passos Ribeiro de. |
| ABSTRACT The aim of this study was to create and test a new mice 3D-voxel phantom named DM_BRA for mice and human first-estimation radiopharmaceutical dosimetry. Previously, the article reviews the state-of-art in animal model development. Images from Digimouse CT database were used in the segmentation and on the generation of the voxelized phantom. Simulations for validation of the DM_BRA model was performed at 0.015, 0.1, 0.5, 1 and 4 MeV photons with heart-source. Specific Absorbed Fractions (SAF) data were compared with literature data. The organ masses of DM_BRA correlated well with existing models based on the same dataset; however, few small organ masses hold significant variations. The SAF data in most simulated cases were statistically equal to a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dosimetry/assay; Mouse phantom/tests; MCNPx Monte Carlo code Computational studies.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100622 |
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| Orzil,Lívia de Lima; Preis,Ingred Sales; Almeida,Iassudara Garcia de; Souza,Patrícia Gomes de; Soares Filho,Paulo Martins; Jacinto,Fabrício Barcelos; Fonseca Júnior,Antônio Augusto. |
| ABSTRACT: A multiplex PCR technique for detection of Brucella spp. in samples of bacterial suspension was validated as a complementary tool in the diagnosis of the disease. This technique allows the characterization of the agent without performing biochemical tests, which greatly reduces the time for a final diagnosis, and provides more security for the analyst by reducing the time of exposure to microorganisms. The validation was performed in accordance with the Manual of Diagnostic Tests from OIE (2008) and following the requirements present in the ABNT NBR ISO/IEC 17025:2005. The mPCR validated in this study identified the different species of Brucella ( Brucella abortus , B. suis , B. ovis e B. melitensis ) of bacterial suspension obtained from the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brucellosis; Molecular identification; Zoonosis; Brucella; Multiplex PCR. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000500847 |
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