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Effect of escitalopram on the processing of emotional faces BJMBR
Alves-Neto,W.C.; Guapo,V.G.; Graeff,F.G.; Deakin,J.F.W.; Del-Ben,C.M..
Serotonin has been implicated in the neurobiology of depressive and anxiety disorders, but little is known about its role in the modulation of basic emotional processing. The aim of this study was to determine the effect of the selective serotonin reuptake inhibitor, escitalopram, on the perception of facial emotional expressions. Twelve healthy male volunteers completed two experimental sessions each, in a randomized, balanced order, double-blind design. A single oral dose of escitalopram (10 mg) or placebo was administered 3 h before the task. Participants were presented to a task composed of six basic emotions (anger, disgust, fear, happiness, sadness, and surprise) that were morphed between neutral and each standard emotion in 10% steps. Escitalopram...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Serotonin; Escitalopram; Facial expression; Emotion; Serotonin reuptake inhibitor.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300010
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Serotonergic modulation of face-emotion recognition BJMBR
Del-Ben,C.M.; Ferreira,C.A.Q.; Alves-Neto,W.C.; Graeff,F.G..
Facial expressions of basic emotions have been widely used to investigate the neural substrates of emotion processing, but little is known about the exact meaning of subjective changes provoked by perceiving facial expressions. Our assumption was that fearful faces would be related to the processing of potential threats, whereas angry faces would be related to the processing of proximal threats. Experimental studies have suggested that serotonin modulates the brain processes underlying defensive responses to environmental threats, facilitating risk assessment behavior elicited by potential threats and inhibiting fight or flight responses to proximal threats. In order to test these predictions about the relationship between fearful and angry faces and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Facial expressions; Serotonin; Defensive behavior.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000400002
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