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Performance assessment of the single photon emission microscope: high spatial resolution SPECT imaging of small animal organs BJMBR
Mejia,J.; Reis,M.A.; Miranda,A.C.C.; Batista,I.R.; Barboza,M.R.F.; Shih,M.C.; Fu,G.; Chen,C.T.; Meng,L.J.; Bressan,R.A.; Amaro Jr,E..
The single photon emission microscope (SPEM) is an instrument developed to obtain high spatial resolution single photon emission computed tomography (SPECT) images of small structures inside the mouse brain. SPEM consists of two independent imaging devices, which combine a multipinhole collimator, a high-resolution, thallium-doped cesium iodide [CsI(Tl)] columnar scintillator, a demagnifying/intensifier tube, and an electron-multiplying charge-coupling device (CCD). Collimators have 300- and 450-µm diameter pinholes on tungsten slabs, in hexagonal arrays of 19 and 7 holes. Projection data are acquired in a photon-counting strategy, where CCD frames are stored at 50 frames per second, with a radius of rotation of 35 mm and magnification factor of one. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tomography; Preclinical imaging; Molecular imaging; Mice.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100936
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Effect of scanner acoustic background noise on strict resting-state fMRI BJMBR
Rondinoni,C.; Amaro Jr,E.; Cendes,F.; Santos,A.C.dos; Salmon,C.E.G..
Functional MRI (fMRI) resting-state experiments are aimed at identifying brain networks that support basal brain function. Although most investigators consider a ‘resting-state’ fMRI experiment with no specific external stimulation, subjects are unavoidably under heavy acoustic noise produced by the equipment. In the present study, we evaluated the influence of auditory input on the resting-state networks (RSNs). Twenty-two healthy subjects were scanned using two similar echo-planar imaging sequences in the same 3T MRI scanner: a default pulse sequence and a reduced “silent” pulse sequence. Experimental sessions consisted of two consecutive 7-min runs with noise conditions (default or silent) counterbalanced across subjects. A self-organizing group...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Resting-state fMRI; Acoustic noise; Default-mode network; Independent component analysis; Granger causality mapping.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000400359
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