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Differentiation of autonomic reflex control begins with cellular mechanisms at the first synapse within the nucleus tractus solitarius 56
Andresen,M.C.; Doyle,M.W.; Bailey,T.W.; Jin,Y.-H..
Visceral afferents send information via cranial nerves to the nucleus tractus solitarius (NTS). The NTS is the initial step of information processing that culminates in homeostatic reflex responses. Recent evidence suggests that strong afferent synaptic responses in the NTS are most often modulated by depression and this forms a basic principle of central integration of these autonomic pathways. The visceral afferent synapse is uncommonly powerful at the NTS with large unitary response amplitudes and depression rather than facilitation at moderate to high frequencies of activation. Substantial signal depression occurs through multiple mechanisms at this very first brainstem synapse onto second order NTS neurons. This review highlights new approaches to the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sensory; Vanilloid; Glutamate; Presynaptic modulation; Autonomic; Visceral; Potassium currents.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000400012
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