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	Provedor de dados Nature Precedings (5) Autor Antony J. Williams (5) Andrew S. I. D. Lang (4) Jean-Claude Bradley (4) Bill Hooker (3) Brent Friesen (3) Cameron Neylon (3) Cedric Tchakounte (3) Daniel Rein (3) David Bulger (3) Hai T. Truong (3) Jenna Mancinelli (3) Jenny Hale (3) Khalid B. Mirza (3) Marshall J. Moritz (3) Matthew Federici (3) Rajarshi Guha (3) Tim Bohinski (3) Chris L. Waller (1) Evan Curtin (1) Mary P. Bradley (1) Mais... Palavra-chave Chemistry (5) Bioinformatics (1) Data Standards (1) Pharmacology (1) Tipo do documento Manuscript (5) Ano 2012 (1) 2011 (1) 2010 (3) País United Kingdom (5)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 5 Primeira ... 1 ... Última Disruptive Strategies for Removing Drug Discovery Bottlenecks Nature Precedings Sean Ekins; Chris L. Waller; Mary P. Bradley; Antony J. Williams. Drug Discovery is shifting focus from the industry to outside partners and in the process creating new bottlenecks, suggesting the need for a more disruptive overhaul. Technologies like high throughput screening (HTS) have moved to a larger number of academic and institutional laboratories in the US, with little apparent coordination or consideration of the outputs and creating a translational gap. While there have been collaborative public private partnerships in Europe to share pharmaceutical data, the USA has lagged behind. Sharing precompetitive computational models may be the next frontier to provide more confidence in the quality of the leads produced and attract investment. We suggest there needs to be an awareness of what research is going on in... Tipo: Manuscript Palavras-chave: Chemistry; Pharmacology; Bioinformatics; Data Standards. Ano: 2012 URL: http://precedings.nature.com/documents/6961/version/1 Open Notebook Science Challenge: Solubilities of Organic Compounds in Organic Solvents Nature Precedings Jean-Claude Bradley; Cameron Neylon; Rajarshi Guha; Antony J. Williams; Bill Hooker; Andrew S. I. D. Lang; Brent Friesen; Tim Bohinski; David Bulger; Matthew Federici; Jenny Hale; Jenna Mancinelli; Khalid B. Mirza; Marshall J. Moritz; Daniel Rein; Cedric Tchakounte; Hai T. Truong. This book contains the results of the Open Notebook Science Solubility Challenge. All experimental measurements are provided with a link to either the laboratory notebook page where the experiment was carried out or to a literature reference. The Challenge was sponsored by Submeta, Nature and Sigma-Aldrich. Tipo: Manuscript Palavras-chave: Chemistry. Ano: 2010 URL: http://precedings.nature.com/documents/4243/version/2 ONS Open Melting Point Collection Nature Precedings Jean-Claude Bradley; Andrew S. I. D. Lang; Antony J. Williams; Evan Curtin. This book represents a PDF version of Dataset ONSMP029 (2706 unique compounds, 7413 measurements) from a project to collect and curate melting points made available as Open Data. This particular collection was selected from the application of a threshold to favor the likelihood of reliability. Specifically, the entire range of averaged values for a data point was set to 0.01 C to 5 C, with at least two different measurements within this range. Measurements were pooled and processed from the following sources: Alfa Aesar, MDPI, Bergstrom, PhysProp, DrugBank, Bell, Oxford MSDS, Hughes, Griffiths and the Chemical Information Validation Spreadsheet. Links to all the information sources and web services are available from the Open Melting Point Resource page:... Tipo: Manuscript Palavras-chave: Chemistry. Ano: 2011 URL: http://precedings.nature.com/documents/6229/version/1 Open Notebook Science Challenge: Solubilities of Organic Compounds in Organic Solvents Nature Precedings Jean-Claude Bradley; Cameron Neylon; Rajarshi Guha; Antony J. Williams; Bill Hooker; Andrew S. I. D. Lang; Brent Friesen; Tim Bohinski; David Bulger; Matthew Federici; Jenny Hale; Jenna Mancinelli; Khalid B. Mirza; Marshall J. Moritz; Daniel Rein; Cedric Tchakounte; Hai T. Truong. This book contains the results of the Open Notebook Science Solubility Challenge. All experimental measurements are provided with a link to either the laboratory notebook page where the experiment was carried out or to a literature reference. The Challenge was sponsored by Submeta, Nature and Sigma-Aldrich. Tipo: Manuscript Palavras-chave: Chemistry. Ano: 2010 URL: http://precedings.nature.com/documents/4243/version/3 Open Notebook Science Challenge: Solubilities of Organic Compounds in Organic Solvents Nature Precedings Jean-Claude Bradley; Cameron Neylon; Rajarshi Guha; Antony J. Williams; Bill Hooker; Andrew S. I. D. Lang; Brent Friesen; Tim Bohinski; David Bulger; Matthew Federici; Jenny Hale; Jenna Mancinelli; Khalid B. Mirza; Marshall J. Moritz; Daniel Rein; Cedric Tchakounte; Hai T. Truong. This book contains the results of the Open Notebook Science Solubility Challenge. All experimental measurements are provided with a link to either the laboratory notebook page where the experiment was carried out or to a literature reference. The Challenge was sponsored by Submeta, Nature and Sigma-Aldrich. Tipo: Manuscript Palavras-chave: Chemistry. Ano: 2010 URL: http://precedings.nature.com/documents/4243/version/1 Registros recuperados: 5 Primeira ... 1 ... Última

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