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Mori, E.; Scheffer, K. C.; Fahl, W. O.; Oliveira, R. N.; Asano, K. M.; Carnieli Jr, P.; Carrieri, M. L.; Kotait, I.. |
Human rabies is still an important public health problem in some Brazilian regions. Usually, ante-mortem diagnosis of rabies is made by demonstration of virus antigen by direct immunofluorescence in corneal or conjunctival smears and skin biopsies; however, this technique has a low sensitivity. Recently, molecular techniques such as the reverse transcriptase polymerase chain reaction (RT-PCR) and nucleic acid sequence based amplification assay (NASBA) have been developed to improve the sensitivity and specificity of ante as well as post-mortem diagnosis of rabies. Rapid and accurate diagnosis of ante-mortem human rabies is essential for effective medical management and to ensure appropriate post-exposure prophylaxis of potential contacts with the patient.... |
Tipo: Info:eu-repo/semantics/article |
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Ano: 2013 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/3098 |
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Pereira, P. M. C.; Lima, J. Y. O.; Barros, R. F.; Ferreira, J. S.; Ikeda, M. A. K.; Fahl, W. O.; Iamamoto, K.; Mori, E.; Asano, K. M.; Ferreira, E.; Achkar, S. M.; Scheffer, K. C.. |
Bats found in Brazil are classified in 9 families, 64 genus and 168 species. They are an important rabies reservoirs and all species can be infected or be the transmitter of rabies virus, independently of their specie classification or feeding habits. This work aimed a survey of bats species originated from counties of Sao Paulo state, which were sent to the diagnostic laboratory of the Pasteur Institute – Sao Paulo. Between August 2009 to October 2012; 9.109 bats specimens were received and submitted to recommended techniques for rabies diagnosis by World Health Organization. From these specimens, 8.421 (92,45%) were classified in family, genus and specie, by morphological and morphometric parameters using bats identification keys. Furthermore, they also... |
Tipo: Info:eu-repo/semantics/article |
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Ano: 2013 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/17386 |
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Jarcovis, R. L. M.; Gamon, T. H. M.; Nogi, K. I.; Fahl, W. O.; Asano, K. M.; Achkar, S. M.; Maiorka, P. C.; Mori, C. M. C.; Mori, E.. |
Introdução e Objetivos: a prova biológica (PB) de inoculação intracerebral (IC) em camundongos com o vírus da raiva (RABV) apresenta sensibilidade diagnóstica superior ao teste de imunofluorescência direta (IFD). No entanto, o tempo necessário para o diagnóstico pela PB é maior que o consumido pela IFD, pois é dependente do período de incubação (PI) viral após inoculação IC. A determinação da duração desses períodos de observação (PO) em camundongos após inoculação IC com RABV foi estabelecida por observações empíricas. Com o intuito de estabelecer a duração do PO dos camundongos da linhagem Swiss inoculados IC com amostras clínicas (SNC, saliva e líquor) positivas para raiva, provenientes de diferentes espécies animais e humanos, oriundos do setor de... |
Tipo: Info:eu-repo/semantics/article |
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Ano: 2015 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/25665 |
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