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	Provedor de dados Genet. Mol. Biol. (2) Autor Azim,M. Kamran (2) Ahmed,Rashida (1) Asif,Huma (1) Aurongzeb,M. (1) Ghias,Kulsoom (1) Khan,Asifullah (1) Khan,Ishtiaq A. (1) Khan,Mumtaz J (1) Madhani,Sarosh (1) Razzak,Safina A (1) Rehmani,Sadiq S (1) Studholme,David J. (1) Mais... Palavra-chave Bacterial genomics (1) Driver mutation (1) Endophyte (1) Head and neck squamous cell carcinoma (HNSCC) (1) Mangifera indica (1) Novel mutation (1) Pakistani population (1) Plant-associated bacteria (1) Whole exome sequencing (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2019 (1) 2016 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Comparative genomics of an endophytic Pseudomonas putida isolated from mango orchard Genet. Mol. Biol. Asif,Huma; Studholme,David J.; Khan,Asifullah; Aurongzeb,M.; Khan,Ishtiaq A.; Azim,M. Kamran. Abstract We analyzed the genome sequence of an endophytic bacterial strain Pseudomonas putida TJI51 isolated from mango bark tissues. Next generation DNA sequencing and short read de novo assembly generated the 5,805,096 bp draft genome of P. putida TJI51. Out of 6,036 protein coding genes in P. putida TJI51 sequences, 4,367 (72%) were annotated with functional specifications, while the remaining encoded hypothetical proteins. Comparative genome sequence analysis revealed that the P. putida TJI51genome contains several regions, not identified in so far sequenced P. putida genomes. Some of these regions were predicted to encode enzymes, including acetylornithine deacetylase, betaine aldehyde dehydrogenase, aldehyde dehydrogenase, benzoylformate... Tipo: Info:eu-repo/semantics/article Palavras-chave: Mangifera indica; Bacterial genomics; Plant-associated bacteria; Endophyte. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000300465 Mutational landscape of head and neck squamous cell carcinomas in a South Asian population Genet. Mol. Biol. Ghias,Kulsoom; Rehmani,Sadiq S; Razzak,Safina A; Madhani,Sarosh; Azim,M. Kamran; Ahmed,Rashida; Khan,Mumtaz J. Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer type globally and contributes significantly to burden of disease in South Asia. In Pakistan, HNSCC is among the most commonly diagnosed cancer in males and females. The increasing regional burden of HNSCC along with a unique set of risk factors merited a deeper investigation of the disease at the genomic level. Whole exome sequencing of HNSCC samples and matched normal genomic DNA analysis (n=7) was performed. Significant somatic single nucleotide variants (SNVs) were identified and pathway analysis performed to determine frequently affected signaling pathways. We identified significant, novel recurrent mutations in ASNS (asparagine synthetase) that may affect substrate... Tipo: Info:eu-repo/semantics/article Palavras-chave: Head and neck squamous cell carcinoma (HNSCC); Whole exome sequencing; Driver mutation; Novel mutation; Pakistani population. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000400526 Registros recuperados: 2 Primeira ... 1 ... Última

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