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| MARQUES,TAMARA R.; BRAGA,MARIANA A.; CESAR,PEDRO H.S.; MARCUSSI,SILVANA; CORRÊA,ANGELITA D.. |
| Abstract: The phenolic extracts of jabuticaba skin flour (JSF) were characterized by HPLC, and evaluated for their modulating action upon phospholipases A2 and proteases of snake venom, aiming at their possible use in the treatment of the various diseases associated with the action of venom toxins. Two types of extracts were prepared from JSF: aqueous and methanolic. These extracts, evaluated at different ratios, (venom: extract, m/m), significantly inhibited the phospholipase activity induced by the venom of Bothrops moojeni and Crotalus durissus terrificus, except for Bothrops atrox venom. The greatest hemolysis inhibitory action was observed for the methanolic extract, when incubated with venoms of B. moojeni and C. durissus terrificus, with inhibitions... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Agro-industrial waste; Phenolic compounds; Venom enzymes as laboratory tools; Clotting; Thrombolysis. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300613 |
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| QUEIROZ,ESTELA R.; ABREU,CELESTE M.P. DE; ROCHA,DENISE A.; SOUSA,RAIMUNDO V. DE; FRÁGUAS,RODRIGO M.; BRAGA,MARIANA A.; CÉSAR,PEDRO H.S.. |
| ABSTRACT Dyslipidemias are associated with the incidence of cardiovascular diseases, obesity, diabetes, hypertension and hepatic steatosis, being the cause of morbidity and mortality. This study investigated the effects of lychee peel flour (PF) on serum levels of total cholesterol (TC), low-density lipoprotein (LDL-c), triacylglycerols (TAG) and various parameters related to obesity, in rats fed a hypercholesterolemic diet. Therefore, 20 male rats were used. In the first 21 days, the animals were fed a hypercholesterolemic diet, except for control group. In the following 21 days, their diets were modified, and they received a standard diet (Control); hypercholesterolemic (Hyper); hypercholesterolemic + 5% PF (PF5) and hypercholesterolemic + 10% PF (PF10).... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cholesterol; Lipid peroxidation; Steatosis; Triacylglycerol; Weight gain. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000100267 |
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