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| Rosa,Roseane Leandra da; Nardi,Geisson Marcos; Januário,Adriana Graziele de Farias; Boçois,Renata; Bagatini,Katiane Paula; Bonatto,Sandro José Ribeiro; Pinto,Andrea de Oliveira; Ferreira,João Ronaldo Notargiacomo; Mariano,Luisa Nathália Bolda; Niero,Rivaldo; Iagher,Fabíola. |
| Luehea divaricata (Malvaceae) is a plant widely used for treatment of various inflammatory and infectious conditions; however few reports discuss its biological properties. The aim of this study was to evaluate the anti-inflammatory and analgesic effects as well as the macrophage activity in mice treated with the hydroalcoholic crude extract of L. divaricata(CLD). Thin layer chromatography revealed presence of epicathequin, stigmasterol, lupeol and α,β-amyrin in the extract. To evaluate the anti-inflammatory and analgesic activities, animals were subjected to paw edema induced by carrageenan test, writhing, formalin and capsaicin tests. Immunomodulatory activity was evaluated by adhesion and phagocytic capacity, lysosomal volume, and reactive oxygen... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Luehea divaricata Mart. & Zucc./pharmacognosy Luehea divaricata Mart. & Zucc./hydroalcoholic crude extract/properties Anti-inflammatories Analgesics Reactive oxygen species. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300599 |
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