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Mesenchymal Stromal Cells Modulate PAF-stimulated Equine Alveolar Macrophages BABT
Michelotto,Pedro Vicente; Bastos,Fernanda Zettel; Barussi,Fernanda Cristina Mendes; Senegaglia,Alexandra Cristina; Nishiyama,Anita.
Abstract Platelet-activating factor (PAF) is a potent proinflammatory mediator that is produced in increased amounts in the lungs of asthmatic humans and horses. The present pilot study, shows that mesenchymal stromal cells can modulate alveolar macrophage function in asthma, interfering in the activity of PAF, being another potential pathway for mesenchymal stromal cells benefits in asthma.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Asthma; Horses; Lung; Platelet-activating factor; Pulmonary inflammation.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100306
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Mineral supplement with pre- and probiotic improves respiratory immune status in yearling racing Thoroughbred horses: preliminary results Ciência Rural
Michelotto Júnior,Pedro Vicente; Barussi,Fernanda Cristina Mendes; Bastos,Fernanda Zettel; Michelotto,Ana Lúcia Lacerda; Weber,Saulo Henrique.
ABSTRACT: There are evidences of intestinal flora influence on the airway immune response. However, this information is scarce with regard to horses. The present preliminary study aimed to investigate the effects of a commercial mineral supplement containing probiotics and prebiotics on the respiratory immune response of horses supplemented with them during the first months of stabling and race training. Twelve TB yearlings were examined at the breeding farm at the beginning of the study (June 2016, henceforth M0) and then reexamined one (July 2016, henceforth M1) and five (November 2016, henceforth M2) months after being stabled at a racetrack in Curitiba, Brazil. Clinical and hematological examinations, airway endoscopy, and tracheal wash (TW) cytology...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Airway inflammation; Endoscopy; Intestinal flora; Prebiotic; Probiotic.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000500651
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