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	Provedor de dados 60 (2) Autor Bazzo,Giovana Carolina (2) Almeida,Aline da Rosa (1) Barreto,Pedro Luiz Manique (1) Crenca,Janine Paula (1) Macedo,Aline Teixeira de (1) Noronha,Carolina Montanheiro (1) Passos,Rhaysa Beatriz dos (1) Pereira,Eduardo Manoel (1) Pezzini,Bianca Ramos (1) Silva,Virgínia Emiliana (1) Zétola,Melissa (1) Mais... Palavra-chave Control (1) Drugs/controlled release (1) Drugs/in vitro study (1) Drugs/in vivo evaluation (1) Ibuprofen/release (1) Microspheres/preparation (1) Nanoparticles Poly ε-caprolactone Thyme Essential Oil Mayonnaise Oxidative stability Antioxidants/adverse effects Thymus Plant Aromatherapy/utilization Butylated Hydroxytoluene/analysis Oxidation/prevention &amp (1) Poly(hydroxybutyrate-co-hydroxyvalerate) (1) Poly(l-lactide) (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2019 (1) 2012 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Evaluation of oxidative stability of mayonnaise containing poly ε- caprolactone nanoparticles loaded with thyme essential oil 60 Passos,Rhaysa Beatriz dos; Bazzo,Giovana Carolina; Almeida,Aline da Rosa; Noronha,Carolina Montanheiro; Barreto,Pedro Luiz Manique. Suspensions of poly ε-caprolactone (PCL) nanoparticles loaded with thyme essential oil were prepared as a natural antioxidant in mayonnaise. Mean particle size was 204.9 ± 2.7 and 240.0 ± 5.5 nm respectively for nanoparticles prepared with PCL alone (NP-C) and for those loaded with thyme essential oil (NP-T). The polydispersity index indicated a homogeneous distribution of all particles, with no significant difference between NP-C and NP-T samples. The nanoparticles showed a large negative charge evidenced by zeta potential rates, indicating high physical stability. The use of PCL as a polymer provided high encapsulation efficiency for thyme essential oil (91.15 ± 2.12 %). DPPH (2,2-diphenyl-1-picrylhydrazyl) method determined IC50 rates were 476.4 ± 33.6... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nanoparticles Poly ε-caprolactone Thyme Essential Oil Mayonnaise Oxidative stability Antioxidants/adverse effects Thymus Plant Aromatherapy/utilization Butylated Hydroxytoluene/analysis Oxidation/prevention & Control. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100505 Microspheres prepared with biodegradable PHBV and PLA polymers as prolonged-release system for ibuprofen: in vitro drug release and in vivo evaluation 60 Bazzo,Giovana Carolina; Macedo,Aline Teixeira de; Crenca,Janine Paula; Silva,Virgínia Emiliana; Pereira,Eduardo Manoel; Zétola,Melissa; Pezzini,Bianca Ramos. In this study, poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) and poly(l-lactide) (PLA) microspheres containing ibuprofen were prepared with the aim of prolonging the drug release. The oil-in-water (O/W) emulsion solvent evaporation technique was used, varying the polymer ratio. All formulations provided spherical particles with drug crystals on the surface and a porous and rough polymeric matrix when PHBV was used and smooth external surface when prepared with PLA. The in vitro dissolution profiles show that the formulation containing PHBV/PLA at the proportion of 30/70 presented the best results in terms of prolonging the ibuprofen release. The analysis of the concentration of ibuprofen in the blood of rats showed that maximum levels were achieved at... Tipo: Info:eu-repo/semantics/article Palavras-chave: Microspheres/preparation; Poly(hydroxybutyrate-co-hydroxyvalerate); Poly(l-lactide); Ibuprofen/release; Drugs/controlled release; Drugs/in vitro study; Drugs/controlled release; Drugs/in vivo evaluation. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000400021 Registros recuperados: 2 Primeira ... 1 ... Última

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