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Pereira Alves,Angela Maria; de Paula,Anderson Luiz; Moreira,Cassio Rafael; Ferrari,Fernanda; Coelho Leal,Jean Paulo; Hatoum,Ualid Saleh; Vieira Silva,Helaine Maruska; Belato Alves,Eder Paulo; de Miranda Neto,Marcilio Hubner; Galvanini,Paulo Alexandre. |
The effects of quercetin supplementation in NADH-diaphorase positive (NADH-d) neurons of streptozotocin-induced diabetic rats was carried in this study. Fifteen male rats were divided into three groups: normoglycemic (N), diabetic (D) and diabetic supplemented with quercetin (DQ). Whole mount preparations of the muscular layer of the ileum underwent NADH-d histochemistry for evidencing the NADH-d neuronal subpopulation. Quantitative analyzes were performed on 30 random fields, and morphometric analyzes in 100 neuronal bodies and nuclei per animal. The supplementation promoted a 44 % reduction in the neuronal density in D group when compared to N group (p <0.001); a 24.5 % reduction was observed in the DQ group when compared to N (p <0.01). Animals in... |
Tipo: Journal article |
Palavras-chave: Diabetes mellitus; Enteric neurons; Quercetin; NADH diaphorase. |
Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000100039 |
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