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| Diniz,Simone Odília Fernandes; Barbosa,Alfredo José Afonso; Araújo,Ivana Durval; Nelson,David Lee; Machado,Leonardo Augusto da Silva; Bernardo Filho,Mário; Cardoso,Valbert Nascimento. |
| In obstructive jaundice, the passage of bacteria and endotoxins through the intestine wall to reach the systemic circulation is associated with septicemia, renal failure and pulmonary dysfunction. The aim of this work was to investigate bacterial translocation utilizing 99mTc-E.coli in an experimental model of obstructive jaundice. The levels of bilirubin in rats that were subjected to ligature of the bile duct were significantly increased when compared to control animals (p < 0.001). The biodistribution results did not show any translocation of 99mTc-E.coli to the mesenteric lymphatic nodules, liver, spleen or lungs of the rats that suffered ligature of the bile duct (p > 0.05). The evaluation of the intestinal permeability using "per os"... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bacterial translocation; Technetium-99m E coli; Obstructive jaundice. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700006 |
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| Moreno,Silvana Ramos Farias; Carvalho,Jorge José de; Rebello,Bernardo; Rocha,Emely Kazan; Timóteo,Margareth de Oliveira; Olej,Beni; Bernardo Filho,Mário; Caldas,Luiz Querino de Araújo. |
| The aim of this study was to evaluate the effect of the extracts of Nectandra membranacea (N. membranacea), Ginkgo biloba (EGb) and Passiflora (PEF) on the morphology of red blood cells (RBC), on the biodistribution of sodium pertechnetate (99mTcO4Na), on the morphology of duodenum and on the labeling of blood constituents (BC, IF-P, IF-BC) with technetium-99m (Tc-99m). Morphometry studies also were performed. The results show that EGb promotes alteration of the labeling of BC, IF-P and IF-BC (p<0.05). The N. membranacea extract does not promote significant alteration of the radiolabeling, and PEF extract alters the IF-P labeling. N. membranacea, EGb and PEF extracts were able to alter the RBC morphology (P<0.05). N. membranacea extract and EGb... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nectandra membranacea (N. membranacea); Ginkgo biloba (EGb); Passiflora edulis flavicarpa (PEF); Blood constituents (BC) labeling; Technetium-99m; Biodistribution. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700027 |
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| Moreno,Silvana Ramos Farias; Carvalho,Jorge José de; Nascimento,Ana Lúcia; Arnobio,Adriano; Olej,Beni; Timóteo,Margareth de Oliveira; Caldas,Luiz Querino de Araújo; Bernardo Filho,Mário. |
| Ginkgo biloba extract (EGb) has been used to treat memory and concentration deficits, acts as platelet activating factor antagonism and prevents against damages caused by free radicals. EGb is a standardized extract that contains 24% flavonoids and 6% terpenoids. The aim of this work was to evaluate the possible influence of an EGb on the ultrastructure of some organs isolated from rats and on the biodistribution of sodium pertechnetate (99mTcO4Na). The animals were treated with EGb and after six days, received 99mTcO4Na. The organs were isolated and fixed for ultrastructural analysis. The results showed that EGb has modified the ultrastructure of kidney, liver and duodenum and altered the biodistribution of 99mTcO4Na (P<0.05). It is speculated that the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ginkgo biloba; Technetium-99m; Biodistribution; Morphology; Ultrastructure. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700030 |
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