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Freeze-drying microscopy in mathematical modeling of a biomaterial freeze-drying BJPS
Borgognoni,Camila Figueiredo; Bevilacqua,Joyce da Silva; Pitombo,Ronaldo Nogueira de Moraes.
Transplantation brings hope for many patients. A multidisciplinary approach on this field aims at creating biologically functional tissues to be used as implants and prostheses. The freeze-drying process allows the fundamental properties of these materials to be preserved, making future manipulation and storage easier. Optimizing a freeze-drying cycle is of great importance since it aims at reducing process costs while increasing product quality of this time-and-energy-consuming process. Mathematical modeling comes as a tool to help a better understanding of the process variables behavior and consequently it helps optimization studies. Freeze-drying microscopy is a technique usually applied to determine critical temperatures of liquid formulations. It has...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Freeze-drying microscopy; Bovine pericardium; Mathematical modeling.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000200003
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