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	Provedor de dados ArchiMer (2) Autor Biard, J (2) Mondeguer, Florence (2) Pouchus, Y (2) Bissett, J (1) Dalgalarrondo, M (1) Mohamed Benkada, M (1) Montagu, M (1) Petit, Karina (1) Roquebert, M (1) Verite, P (1) Mais... Palavra-chave Marine fungi (2) Antifungal (1) Electrospray ionisation multiple stage mass spectrometry ion trap (ESI MSn IT) (1) Griseofulvin (1) Marine products (1) Mass spectrometry ESI IT/MS (1) Penicillium waksmanii (1) Short peptaibols (1) Trichoderma longibrachiatum (1) Mais... Tipo do documento Text (2) Ano 2006 (1) 2004 (1) País France (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Detection of griseofulvin in a marine strain of Penicillium waksmanii by ion trap mass spectrometry ArchiMer Petit, Karina; Mondeguer, Florence; Roquebert, M; Biard, J; Pouchus, Y. A marine strain of Penicillium waksmanii Zaleski was isolated from a sample of seawater from shellfish-farming area in the Loire estuary (France). The in vitro marine culture showed an important antifungal activity. Bioassay-guided fractionation was used to purify the crude extract. Dereplication by electrospray-ion trap/mass spectrometry (ESI-IT/MS) afforded the identification of the antifungal compound, after a semi-purification consisting of two stages. A comparison of the ionic composition between the active and the non-active fractions allowed the detection of a monocharged ion at m/z 353 containing a chlorine atom, which could be attributed to the antifungal griseofulvin [C17H17ClO6+H](+). Multi-stage fragmentation (MSn) confirmed the identity of the... Tipo: Text Palavras-chave: Mass spectrometry ESI IT/MS; Griseofulvin; Antifungal; Marine fungi; Penicillium waksmanii. Ano: 2004 URL: http://archimer.ifremer.fr/doc/2004/publication-673.pdf New short peptaibols from a marine Trichoderma strain ArchiMer Mohamed Benkada, M; Montagu, M; Biard, J; Mondeguer, Florence; Verite, P; Dalgalarrondo, M; Bissett, J; Pouchus, Y. The production of peptaibols by a marine-related Trichoderma longibrachiatum strain was studied using electrospray ionisation multiple-stage ion trap mass spectrometry (ESI-MSn-IT) and gas chromatography/electron impact mass spectrometry (GC/EI-MS). Two major groups of peptaibols were identified, those with long sequences (20 amino acids) and others with short sequences (11 amino acids). This paper describes the methodology used to establish the sequences of short peptaibols in a mixture without previous individual separation. Nine peptaibols were identified. Among them, eight are new, namely as trichobrachin A I-IV (Aib(9)-Pro(10) sequence) and as trichobrachin B I-IV (Val(9)-Pro(10) sequence). Original Pro(6)-Val(7) and Val(9)-Pro(10) sequences have to... Tipo: Text Palavras-chave: Trichoderma longibrachiatum; Marine fungi; Marine products; Electrospray ionisation multiple stage mass spectrometry ion trap (ESI MSn IT); Short peptaibols. Ano: 2006 URL: http://archimer.ifremer.fr/doc/2006/publication-1550.pdf Registros recuperados: 2 Primeira ... 1 ... Última

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