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Time of catheter removal in candidemia and mortality BJID
Nucci,Marcio; Braga,Paula Rocha; Nouér,Simone A.; Anaissie,Elias.
ABSTRACT Background: The impact of central venous catheter (CVC) removal on the outcome of patients with candidemia is controversial, with studies reporting discrepant results depending on the time of CVC removal (early or any time during the course of candidemia). Objective: Evaluate the effect of time to CVC removal, early (within 48 h from the diagnosis of candidemia) vs. removal at any time during the course of candidemia, on the 30-day mortality. Methods: Retrospective cohort study of 285 patients with candidemia analyzing CVC removal within 48 h (first analysis) or at any time (second analysis). Results: A CVC was in place in 212 patients and was removed in 148 (69.8%), either early (88 patients, 41.5%) or late (60 patients, 28.3%). Overall, the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candidemia; Central venous catheter; Mortality; Multivariate analysis; Candida.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000600455
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Secular trends of candidemia at a Brazilian tertiary care teaching hospital BJID
Braga,Paula Rocha; Cruz,Isabela L.; Ortiz,Isadora; Barreiros,Gloria; Nouér,Simone A.; Nucci,Marcio.
ABSTRACT Background Candidemia is the most frequent invasive fungal disease in hospitalized patients, and is associated with high mortality rates. The main objective of this study was to evaluate changes in the epidemiology of candidemia at a tertiary care hospital in a 21-year period. Methods We evaluated all episodes of candidemia diagnosed between 1996 and 2016 at a University-affiliated tertiary care hospital in Brazil. We arbitrarily divided the study period in 3: 1996-2002 (period 1), 2003-2009 (period 2) and 2010-2016 (period 3). Incidence rates were calculated using hospital admissions as denominator. Results We observed 331 episodes of candidemia. The incidence was 1.30 episodes per 1000 admissions, with no significant change over time. Candida...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candidemia; Epidemiology; Fungemia; Candida.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000400273
Registros recuperados: 2
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