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	Provedor de dados BJPS (2) BJID (1) Autor Brito,Monique Araújo de (3) Barros,Rosana Rocha (1) Castilho,Selma Rodrigues de (1) Duarte,Rafael Silva (1) Kegele,Fabíola Cristina Oliveira (1) Paula,Geraldo Renato de (1) Piccoli,Nilo Jorge (1) Mais... Palavra-chave Bacteriuria (1) Brazilian public health system/assistance/HIV/AIDS. (1) Cheminformatics (1) Drugs/molecular properties (1) Drugs/teaching (1) Fluoroquinolone resistance (1) Genetic diversity (1) Medicinal chemistry/teaching-learning process (1) Pharmaceutical assistance/Brazil (1) Pharmaceutical assistance/evaluation (1) Pharmacokinetics/teaching (1) Pharmacy/education (1) Streptococcus agalactiae (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Ano 2017 (1) 2012 (1) 2011 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Molecular characterization of the first fluoroquinolone resistant strains of Streptococcus agalactiae isolated in Brazil BJID Barros,Rosana Rocha; Kegele,Fabíola Cristina Oliveira; Paula,Geraldo Renato de; Brito,Monique Araújo de; Duarte,Rafael Silva. Three isolates of Streptococcus agalactiae, recovered from residents of the metropolitan area of Rio de Janeiro with significant bacteriuria, were found to be resistant to levofloxacin. Determination of the minimal inhibitory concentration (MIC) confirmed one isolate as intermediate and two as resistant to levofloxacin. No reduction in levofloxacin MIC was observed with reserpine, indicating that resistance was not caused by an efflux mechanism. Typical point mutations were observed in the quinolone resistance determinant region of gyrA and parC. Other point mutations in parC generated novel altered codons: Ser80→Pro in the intermediate resistance isolate, and Gly128→Asp in a resistant isolate. Through molecular modeling, it was possible to observe that... Tipo: Info:eu-repo/semantics/other Palavras-chave: Fluoroquinolone resistance; Bacteriuria; Genetic diversity; Streptococcus agalactiae. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000500013 Pharmacokinetic study with computational tools in the medicinal chemistry course BJPS Brito,Monique Araújo de. To improve the teaching-learning process in the Medicinal Chemistry course, new strategies have been incorporated into practical classes of this fundamental discipline of the pharmaceutical curriculum. Many changes and improvements have been made in the area of medicinal chemistry so far, and students should be prepared for these new approaches with the use of technological resources in this field. Practical activities using computational techniques have been directed to the evaluation of chemical and physicochemical properties that affect the pharmacokinetics of drugs. Their objectives were to allow students to know these tools, to learn how to access them, to search for the structures of drugs and to analyze results. To the best of our knowledge, this is... Tipo: Info:eu-repo/semantics/article Palavras-chave: Medicinal chemistry/teaching-learning process; Pharmacy/education; Cheminformatics; Pharmacokinetics/teaching; Drugs/molecular properties; Drugs/teaching. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400017 Assessment of pharmaceutical services in HIV/AIDS health units in the city of Niterói, Brazil BJPS Piccoli,Nilo Jorge; Brito,Monique Araújo de; Castilho,Selma Rodrigues de. ABSTRACT This study aimed to conduct an assessment of pharmaceutical services in HIV/AIDS in the city of Niteroi, Brazil, with emphasis on management. It was done a descriptive cross-sectional study, and the approach used was a normative assessment focused on quality. The indicators used were analyzed individually or grouped according to the components of pharmaceutical services. The assessment identified some good points, especially regarding the good availability of ARVs, and good guide patients in the use of these drugs, and also some problems such as low levels of compliance in relation to good dispensing practices criteria and storage and a high time for the distribution of medicines. The result was a degree of 50.3% compliance with the quality... Tipo: Info:eu-repo/semantics/article Palavras-chave: Pharmaceutical assistance/evaluation; Pharmaceutical assistance/Brazil; Brazilian public health system/assistance/HIV/AIDS.. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200610 Registros recuperados: 3 Primeira ... 1 ... Última

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