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LIPID VESICLES: APPLICATIONS, PRINCIPAL COMPONENTS AND METHODS USED IN THEIR FORMULATIONS. A REVIEW Acta biol.Colomb.
CAMILO,Cicera J.; LEITE,Débora O. D.; SILVA,Angelo R. A. e; MENEZES,Irwin R. A.; COUTINHO,Henrique D. M.; COSTA,José G. M. da.
ABSTRACT Liposomes and niosomes are currently the most studied lipid vesicles in the nanomedicine field. The system formed by a phospholipid bilayer in aqueous medium allows these vesicles to carry both hydrophilic and lipophilic compounds, providing an increase in solubility of drugs already used in conventional therapy. The focus on the development of these vesicles should be directed to determining the ideal composition, with low toxicity, biocompatibility and which remains stable for long periods. These characteristics are related to the components used for formulation and the substances that will be encapsulated. Another important point relates to the methods used during formulation, which are important in determining the type of vesicle formed,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Components; Formulation; Liposomes; Nanomedicine; Niosomes.
Ano: 2020 URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-548X2020000200339
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