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| ANDRADE,PRISCILA M. DE; MELO,DAIANA C. DE; ALCOBA,ANA ELISA T.; FERREIRA JÚNIOR,WALNIR G.; PAGOTTI,MARIANA C.; MAGALHÃES,LIZANDRA G.; SANTOS,TAINÁ C.L. DOS; CROTTI,ANTÔNIO E.M.; ALVES,CASSIA C.F.; MIRANDA,MAYKER L.D.. |
| Abstract Leishmaniasis is an endemic disease caused by protozoa of the genus Leishmania, which affects around two million people worldwide. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Medicinal and aromatic plants constitute a major source of natural organic compounds. In this study, the leaf essential oil of Cryptocarya aschersoniana was obtained by hydrodistillation in a Clevenger-type apparatus, and the chemical composition was analyzed by GC-MS and GC-FID. The essential oil of these species was predominantly constituted by monoterpene hydrocarbons (48.8%). Limonene (42.3%), linalool (9.7%) and nerolidol (8.6%) were the main constituents in the oil of C. aschersoniana. The in vitro... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptocarya aschersoniana; Lauraceae; Essential oil; Leishmania amazonensis; Cytotoxic activity. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000602671 |
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| GONÇALVES,REGIANE; AYRES,VANESSA F.S.; CARVALHO,CARLOS E.; SOUZA,MARIA G.M.; GUIMARÃES,ANDERSON C.; CORRÊA,GEONE M.; MARTINS,CARLOS H.G.; TAKEARA,RENATA; SILVA,ELIANE O.; CROTTI,ANTÔNIO E.M.. |
| ABSTRACT Abnormal multiplication of oral bacteria causes dental caries and dental plaque. These diseases continue to be major public health concerns worldwide, mainly in developing countries. In this study, the chemical composition and antimicrobial activity of the essential oil of Vitex agnus-castus leaves (VAC‒EO) collected in the North of Brazil against a representative panel of cariogenic bacteria were investigated. The antimicrobial activity of VAC-EO was evaluated in terms of its minimum inhibitory concentration (MIC) values by using the broth microdilution method in 96-well microplates. The chemical constituents of VAC-EO were identified by gas chromatography (GC‒FID) and gas chromatography‒mass spectrometry (GC‒MS). VAC‒EO displayed some activity... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Streptococcus mutans; 1-8-cineole; Cariogenic bacteria; Oral pathogens. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000602825 |
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| LEMES,RAIANE S.; ALVES,CASSIA C.F.; ESTEVAM,ELISÂNGELA B.B.; SANTIAGO,MARIANA B.; MARTINS,CARLOS H.G.; SANTOS,TAINÁ C.L. DOS; CROTTI,ANTÔNIO E.M.; MIRANDA,MAYKER L.D.. |
| ABSTRACT Tooth decay is a major public health problem which affects a large number of people in several countries. Even though more than 700 bacterial species have been detected in the oral cavity, Streptococcus and Lactobacillus stand out as the genera that cause tooth decay and other periodontal diseases. In this study, essential oils from Citrus aurantifolia leaves (CL-EO) and fruit peel (CP-EO) were obtained by hydrodistillation by a Clevenger-type apparatus whereas their chemical composition was analyzed by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Limonene (77.5 %), linalool (20.1 %), citronellal (14.5 %) and citronellol (14.2 %) were the main constituents found in the essential oils from... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Citrus aurantifolia; Limonene; Cariogenic bacteria; Essential oils; Oral pathogens. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401285 |
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