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	Provedor de dados BJPS (2) Autor Cabral,Lúcio Mendes (2) Rodrigues,Carlos Rangel (2) Sousa,Valéria Pereira de (2) Deccache,Daniela Soares (1) Lira,Luiz Marcelo (1) Lourenço,Alexandre Lopes (1) Neves,Guilherme Ferreira (1) Santos,Elisabete Pereira dos (1) Mais... Palavra-chave Anti-aging dermocosmetic formulations/quantitative analysis (1) Clopidogrel/crystalline forms/patents (1) Clopidogrel/crystalline forms/physicochemical characterization (1) DMAE glycolate (1) High Performance Liquid Chromatography-RP/quantitative analysis (1) Non-aqueous potentiometric titration/quantitative analysis (1) Polymorphism (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2014 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Development of methodologies for dimethylaminoethanol glycolate assay in association with sunscreens in dermocosmetic formulation BJPS Deccache,Daniela Soares; Santos,Elisabete Pereira dos; Cabral,Lúcio Mendes; Rodrigues,Carlos Rangel; Sousa,Valéria Pereira de. DMAE glycolate (DG) and sunscreens have been used associated in anti-aging dermocosmetic formulations. Despite extensive use of these substances, methods for quantification of DG as raw material and in cosmetic formulations, especially when associated, are not described in the literature. RP-HPLC and non-aqueous titration methods, with determination potentiometric end-point (PT), were developed and validated for rapid assay of DG as raw material and in a topic emulsion in association with sunscreens. Both methods are simple, selective, linear, accurate and precise. The PT method was chosen for stability study of DG in the formulation developed. The proposed formulation presented good stability performance as regards aspect, pH, apparent viscosity, and SPF,... Tipo: Info:eu-repo/semantics/article Palavras-chave: DMAE glycolate; Anti-aging dermocosmetic formulations/quantitative analysis; High Performance Liquid Chromatography-RP/quantitative analysis; Non-aqueous potentiometric titration/quantitative analysis. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400012 Assessment of analytical techniques for characterization of crystalline clopidogrel forms in patent applications BJPS Lira,Luiz Marcelo; Lourenço,Alexandre Lopes; Neves,Guilherme Ferreira; Sousa,Valéria Pereira de; Rodrigues,Carlos Rangel; Cabral,Lúcio Mendes. The aim of this study was to evaluate two important aspects of patent applications of crystalline forms of drugs: (i) the physicochemical characterization of the crystalline forms; and (ii) the procedure for preparing crystals of the blockbuster drug clopidogrel. To this end, searches were conducted using online patent databases. The results showed that: (i) the majority of patent applications for clopidogrel crystalline forms failed to comply with proposed Brazilian Patent Office guidelines. This was primarily due to insufficient number of analytical techniques evaluating the crystalline phase. In addition, some patent applications lacked assessment of chemical/crystallography purity; (ii) use of more than two analytical techniques is important; and (iii)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Clopidogrel/crystalline forms/physicochemical characterization; Clopidogrel/crystalline forms/patents; Polymorphism. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000200229 Registros recuperados: 2 Primeira ... 1 ... Última

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