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Minimum alveolar concentration of isoflurane in dogs administered two morphine doses Ciência Rural
Coelho,Karina; Monteiro,Eduardo Raposo; Bressan,Thais Feres; Monteiro,Betânia Souza; Campagnol,Daniela; Alievi,Marcelo Meller.
ABSTRACT: This study aimed to evaluate the effects of intramuscular 0.5mg kg-1 (MOR0.5) and 1.0mg kg-1 (MOR1.0) morphine premedication on the minimum alveolar concentration of isoflurane (ISOMAC) in dogs. Eighteen client-owned female dogs were scheduled for elective ovariohysterectomy. Dogs received intramuscular MOR0.5 or MOR1.0 as premedication and propofol IV for induction of anesthesia. Isoflurane was delivered for maintenance of anesthesia and dogs were maintained under normocapnia and normothermia. Determinations of the ISOMAC were conducted by use of the “up-and-down” method. Noxious stimulus (placement of Backhaus towel clamps, a midline skin incision and subcutaneous tissue dissection) was delivered approximately 50 minutes after premedication...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Autonomic response; Canine; Inhalational anesthetics; Opioids.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001100601
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Minimum alveolar concentration of isoflurane in dogs administered a single intramuscular injection of racemic or S (+)-ketamine after premedication with acepromazine-morphine Ciência Rural
Bressan,Thais Feres; Monteiro,Eduardo Raposo; Coelho,Karina; Monteiro,Betânia Souza; Campagnol,Daniela.
ABSTRACT: The present study evaluated the minimum alveolar concentration of isoflurane (ISOMAC) in twenty three dogs premedicated with acepromazine (0.02mgkg-1) and morphine (0.5mgkg-1) and administered racemic (RK) or S(+)-ketamine (SK). Dogs randomly received a single dose (3mgkg-1, IM) of either RK or SK 15minutes after anesthetic induction with propofol. The ISOMAC was determined by the up-and-down method. Approximately 20 minutes after administration of RK or SK, a surgical noxious stimulus was applied and the response evaluated. The ISOMAC was 0.50±0.01% in the RK group (n=10) and 0.31±0.04% in the SK group (n=13). The ISOMAC was 38% lower in the SK group compared to the RK group. Results of the present study revealed that in dogs premedicated with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dissociative anesthesia; MAC; NMDA antagonist; Phencyclidine derivative; Preemptive analgesia.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000100601
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