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Prescription of anorectic and benzodiazepine drugs through notification B prescriptions in Natal, Rio Grande do Norte, Brazil 60
Nappo,Solange Aparecida; Carlini,Elisaldo Araújo; Araújo,Maria Dalva; Moreira,Lúcio Flávio Sousa.
A study was conducted on 22,158 special B prescriptions (notificações B) containing amphetamine-type anorectic drugs or benzodiazepines, obtained from compounding pharmacies or drugstores located in the city of Natal, RN, Brazil. The data obtained were compared with those from other Brazilian cities. Results showed that compounding pharmacies dispensed 85.4% of the prescriptions, indicating that these pharmacies filled out nearly 10 times more of these prescriptions than did the drugstores. The majority (83.5%) of B prescriptions issued for the compounding pharmacies were for women, where the female/male patient ratio ranged from 7.1/1.0 for mazindol to 10.3/1.0 for amfepramone. Similar results were obtained for the benzodiazepines with ratios of 1.9/1.0...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anorectic/prescription; Benzodiazepine/prescription; Obesity/treatment; Medicines/rational use; Compounded medicine; Compounding pharmacy.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200017
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Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol 60
Pires,Júlia Movilla; Mendes,Fúlvio Rieli; Pires,Ana Paula Salum; Yonamine,Maurício; Amaral,José Luiz Gomes do; Carlini,Elisaldo Araújo.
ABSTRACT Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. The main active components of ayahuasca are dimethyltryptamine and the harmala alkaloids with β-carboline structure acting as monoamine oxidase A inhibitors. This combination produces a pronounced activation of serotonergic pathways and presents potential interaction with other psychotropics. The objective of this study was to investigate the possible interactions between ayahuasca and agents employed in general anesthesia. The pharmacological interactions between ayahuasca and morphine or propofol were evaluated in mice using doses of 12, 120 and 1200 mg/kg (0.1 to 10 times the average dose consumed by humans in religious...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ayahuasca; Analgesic effect; Pharmacological interactions; Morphine; Propofol; Β-Carbolines..
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100609
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