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A clinical gamma camera-based pinhole collimated system for high resolution small animal SPECT imaging BJMBR
Mejia,J.; Galvis-Alonso,O.Y.; Castro,A.A.de; Braga,J.; Leite,J.P.; Simões,M.V..
The main objective of the present study was to upgrade a clinical gamma camera to obtain high resolution tomographic images of small animal organs. The system is based on a clinical gamma camera to which we have adapted a special-purpose pinhole collimator and a device for positioning and rotating the target based on a computer-controlled step motor. We developed a software tool to reconstruct the target’s three-dimensional distribution of emission from a set of planar projections, based on the maximum likelihood algorithm. We present details on the hardware and software implementation. We imaged phantoms and heart and kidneys of rats. When using pinhole collimators, the spatial resolution and sensitivity of the imaging system depend on parameters such as...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pinhole collimator; SPECT; Small animal organs; Maximum likelihood; Instrumentation; Image processing.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001200004
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