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	Provedor de dados BJMBR (2) Autor Castro-Faria-Neto,H.C. (2) Aguiar-Nemer,A.S. (1) Alexandre-Moreira,M.S. (1) Barros,F.R. (1) Castro,C.L. (1) Freire-de-Lima,C.G. (1) Peçanha,L.M.T. (1) Piuvezam,M.R. (1) Rocha,E.M.S. (1) Silva-Fonseca,V.A. (1) Trindade,M.N. (1) Mais... Palavra-chave Alcohol (1) Cissampelos sympodialis (1) Cytokines (1) Estrogens (1) Interleukin-10 (1) Macrophage (1) Nitric oxide (1) Sepsis (1) Trypanosoma cruzi (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2013 (1) 2003 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Effect of chronic ethanol consumption in female rats subjected to experimental sepsis BJMBR Castro,C.L.; Aguiar-Nemer,A.S.; Castro-Faria-Neto,H.C.; Barros,F.R.; Rocha,E.M.S.; Silva-Fonseca,V.A.. The objective of this research was to evaluate the interference of ethanol consumption by female rats with cytokines involved in the sepsis process and its correlation with mortality, the main outcome of sepsis. Female Wistar rats in estrus phase were evaluated in three experiments. Experiment 1 (n=40) was performed to determine survival rates. Experiment 2 (n=69) was designed for biochemical analysis, measurement of cytokine and estrogen levels before and after sepsis, and experiment 3 (n=10) was performed to evaluate bacterial growth by colony counts of peritoneal fluid. In all experiments, treated animals were exposed to a 10% ethanol/water solution (v/v) as the single drinking source, while untreated animals were given tap water. After 4 weeks, sepsis... Tipo: Info:eu-repo/semantics/article Palavras-chave: Alcohol; Sepsis; Cytokines; Estrogens. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001201033 Cissampelos sympodialis Eichl (Menispermaceae) leaf extract induces interleukin-10-dependent inhibition of Trypanosoma cruzi killing by macrophages BJMBR Alexandre-Moreira,M.S.; Freire-de-Lima,C.G.; Trindade,M.N.; Castro-Faria-Neto,H.C.; Piuvezam,M.R.; Peçanha,L.M.T.. The aqueous fraction of the ethanolic extract (AFL) of Cissampelos sympodialis Eichl (Menispermaceae), popularly known as milona, has been shown to have both immunosuppressive and anti-inflammatory effects. In the present study we investigated the modulation of macrophage antimicrobicidal activity by in vitro treatment with the extract from C. sympodialis. Normal and thioglycolate-elicited mouse peritoneal macrophages were infected in vitro with the protozoan Trypanosoma cruzi DM28c clone. We observed that the AFL (used at doses ranging from 13 to 100 µg/ml) increased T. cruzi growth and induced a 75% reduction in nitric oxide production. This inhibition could be mediated by the stimulation of macrophage interleukin-10 (IL-10) secretion since the in vitro... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cissampelos sympodialis; Macrophage; Trypanosoma cruzi; Nitric oxide; Interleukin-10. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000200006 Registros recuperados: 2 Primeira ... 1 ... Última

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