|
|
| Cavaleiro,J. S.; Trindade,B. C.; Balderramas,H. A.; Haanwinckel,M. C.; Pinto,J. G. G.; Oliveira,S. L.; Paes,A. C.. |
| Mice genetically selected for high (H) and low (L) antibody production (Selection IV-A) were used as murine experimental model. The aim of the present work was to evaluate the macrophagic activity and to characterize the immune response in Mycobacterium bovis-AN5 infected mice (3X10(7) bacteria). The response profile previously observed in such strains was not similar to that obtained during M. bovis infection; however, it corroborated works carried out using Selection I, which is very similar to Selection IV-A regarding infection by M. tuberculosis and Bacillus Calmette-Guérin (BCG). Considering bacterial recovery, L IV-A mice showed higher control of the infectious process in the lungs than in the spleen, whereas H IV-A mice presented more resistance in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immune response; Mycobacterium bovis; Biozzi mice. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000300006 |
| |
