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	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Cavasini,CE (1) Mattos,LC (1) Oliveira,AP (1) Palavra-chave Chagas' cardiomyopathy (1) Chagas' disease (1) DARC antigen (1) Duffy blood-group system (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2011 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Chagas' disease and Duffy antigen/receptor for chemokine (DARC): a mini-review J. Venom. Anim. Toxins incl. Trop. Dis. Oliveira,AP; Mattos,LC; Cavasini,CE. Duffy gene (FY) codifies the transmembrane glycoprotein Duffy (gp-Fy) of 35 to 43 kDa which is moderately immunogenic. This glycoprotein is polymorphic, and constitutes the antigens of the Duffy histo-blood system which were designated receptors for chemokines and denominated DARC (Duffy antigen/receptor for chemokine). This receptor has an important role in the regulation of chemokine levels in the circulation, as it binds and adsorbs them on the surface of red cells as a reservoir. It plays a "sink" role, which can contribute to homeostasis by removing inflammatory chemokines from circulation as well as maintaining them in plasmatic levels. Chronic Chagas' cardiopathy (CCC) is the most frequent form of the disease. It is an inflammatory disease, in which... Tipo: Info:eu-repo/semantics/article Palavras-chave: DARC antigen; Duffy blood-group system; Chagas' disease; Chagas' cardiomyopathy. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000300005 Registros recuperados: 1 Primeira ... 1 ... Última

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