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Cayres-Vallinoto,Izaura Maria Vieira; Vallinoto,Antonio Carlos Rosário; Pena,Giselle Priscila dos Anjos; Azevedo,Vânia Nakauth; Machado,Luiz Fernando Almeida; Ishak,Marluísa de Oliveira Guimarães; Ishak,Ricardo. |
Abstract JC virus (JCV) is a member of the Polyomaviridae family and is associated to a severe disease known as progressive multifocal leukoencephalopathy, PML, which is gradually increasing in incidence as an opportunistic infection among AIDS patients. The present study aimed to investigate the occurrence of JCV among HIV-1 carriers including their types and molecular subtypes and the possible association with disease. Urine samples from 66 HIV-1 infected subjects were investigated for the presence of the virus by amplifying VP1 (215 bp) and IG (610 bp) regions using the polymerase chain reaction. JCV was detected in 32% of the samples. The results confirmed the occurrence of type B (subtype Af2); in addition, another polyomavirus, BKV, was also detected... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: JCV; HIV-1; Co-infection; Brazilian Amazon region. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000400360 |
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Guerreiro,João Farias; Ribeiro-dos-Santos,Ândrea Kely Campos; Santos,Eduardo José Melo dos; Vallinoto,Antonio Carlos Rosário; Cayres-Vallinoto,Izaura Maria Vieira; Aguiar,Gilberto Ferreira de Souza; Santos,Sidney Emanuel Batista dos. |
The Amazon region of Brazil includes communities founded by escaped slaves, some of which still remain relatively isolated. We studied two such Afro-Brazilian communities (Pacoval and Curiau), in the rural area of Alenquer, Pará, and in the metropolitan region of Macapá, Amapá, respectively. Among 12 blood loci, alleles considered as markers of African ancestry, such as HBB*S, HBB*C, TF*D1, HP*2M, ABO*B, RH*D-, and CA2*2 were found at frequencies that are expected for populations with a predominantly African origin. Estimates of interethnic admixture indicated that the degree of the African component in Curiau (74%) is higher than that of Pacoval (44%); an Amerindian contribution was not detected in Curiau. Estimated values of African ancestry fit well... |
Tipo: Info:eu-repo/semantics/article |
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Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571999000200004 |
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